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TAF3 (TATA-box binding protein associated factor 3)

Identity

Alias (NCBI)TAF140
TAFII-140
TAFII140
HGNC (Hugo) TAF3
HGNC Alias symbTAF140
TAFII140
HGNC Previous nameTAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140 kD
 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
LocusID (NCBI) 83860
Atlas_Id 74469
Location 10p14  [Link to chromosome band 10p14]
Location_base_pair Starts at 7818505 and ends at 8016631 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GATA3 (10p14) / TAF3 (10p14)HSP90AB1 (6p21.1) / TAF3 (10p14)PTMS (12p13.31) / TAF3 (10p14)
TAF3 (10p14) / ATP5C1 (10p14)TAF3 (10p14) / DNAJC1 (10p12.31)TAF3 (10p14) / ZDHHC14 (6q25.3)
ZNF197 (3p21.31) / TAF3 (10p14)TAF3 DNAJC1TAF3 ATP5C1
TAF3 ZDHHC14HSP90AB1 TAF3GATA3 TAF3
PTMS TAF3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(9;10)(p13;p14) PAX5/TAF3
t(9;10)(p13;p14) PAX5/TAF3


External links

 

Nomenclature
HGNC (Hugo)TAF3   17303
Cards
Entrez_Gene (NCBI)TAF3    TATA-box binding protein associated factor 3
AliasesTAF140; TAFII-140; TAFII140
GeneCards (Weizmann)TAF3
Ensembl hg19 (Hinxton)ENSG00000165632 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165632 [Gene_View]  ENSG00000165632 [Sequence]  chr10:7818505-8016631 [Contig_View]  TAF3 [Vega]
ICGC DataPortalENSG00000165632
TCGA cBioPortalTAF3
AceView (NCBI)TAF3
Genatlas (Paris)TAF3
SOURCE (Princeton)TAF3
Genetics Home Reference (NIH)TAF3
Genomic and cartography
GoldenPath hg38 (UCSC)TAF3  -     chr10:7818505-8016631 +  10p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF3  -     10p14   [Description]    (hg19-Feb_2009)
GoldenPathTAF3 - 10p14 [CytoView hg19]  TAF3 - 10p14 [CytoView hg38]
ImmunoBaseENSG00000165632
Genome Data Viewer NCBITAF3 [Mapview hg19]  
OMIM606576   
Gene and transcription
Genbank (Entrez)AJ292190 AK123254 AK307521 AK307657 AL117661
RefSeq transcript (Entrez)NM_031923
Consensus coding sequences : CCDS (NCBI)TAF3
Gene ExpressionTAF3 [ NCBI-GEO ]   TAF3 [ EBI - ARRAY_EXPRESS ]   TAF3 [ SEEK ]   TAF3 [ MEM ]
Gene Expression Viewer (FireBrowse)TAF3 [ Firebrowse - Broad ]
GenevisibleExpression of TAF3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83860
GTEX Portal (Tissue expression)TAF3
Human Protein AtlasENSG00000165632-TAF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VWG9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VWG9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VWG9
PhosPhoSitePlusQ5VWG9
Domaine pattern : Prosite (Expaxy)ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)   
Domains : Interpro (EBI)BTP    Histone-fold    Zinc_finger_PHD-type_CS    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)Bromo_TP (PF07524)    PHD (PF00628)   
Domain families : Pfam (NCBI)pfam07524    pfam00628   
Domain families : Smart (EMBL)BTP (SM00576)  PHD (SM00249)  
Conserved Domain (NCBI)TAF3
PDB (RSDB)5C13    5WXG    5WXH    5XMY    6MZD    6MZL   
PDB Europe5C13    5WXG    5WXH    5XMY    6MZD    6MZL   
PDB (PDBSum)5C13    5WXG    5WXH    5XMY    6MZD    6MZL   
PDB (IMB)5C13    5WXG    5WXH    5XMY    6MZD    6MZL   
Structural Biology KnowledgeBase5C13    5WXG    5WXH    5XMY    6MZD    6MZL   
SCOP (Structural Classification of Proteins)5C13    5WXG    5WXH    5XMY    6MZD    6MZL   
CATH (Classification of proteins structures)5C13    5WXG    5WXH    5XMY    6MZD    6MZL   
SuperfamilyQ5VWG9
AlphaFold pdb e-kbQ5VWG9   
Human Protein Atlas [tissue]ENSG00000165632-TAF3 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q5VWG9
IntAct (EBI)Q5VWG9
BioGRIDTAF3
STRING (EMBL)TAF3
ZODIACTAF3
Ontologies - Pathways
QuickGOQ5VWG9
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  p53 binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription factor TFIID complex  transcription factor TFIID complex  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  RNA polymerase II general transcription initiation factor activity  nuclear membrane  negative regulation of DNA-binding transcription factor activity  metal ion binding  protein heterodimerization activity  maintenance of protein location in nucleus  transcription regulator inhibitor activity  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  p53 binding  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription factor TFIID complex  transcription factor TFIID complex  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  RNA polymerase II general transcription initiation factor activity  nuclear membrane  negative regulation of DNA-binding transcription factor activity  metal ion binding  protein heterodimerization activity  maintenance of protein location in nucleus  transcription regulator inhibitor activity  regulation of signal transduction by p53 class mediator  
NDEx NetworkTAF3
Atlas of Cancer Signalling NetworkTAF3
Wikipedia pathwaysTAF3
Orthology - Evolution
OrthoDB83860
GeneTree (enSembl)ENSG00000165632
Phylogenetic Trees/Animal Genes : TreeFamTAF3
Homologs : HomoloGeneTAF3
Homology/Alignments : Family Browser (UCSC)TAF3
Gene fusions - Rearrangements
Fusion : QuiverTAF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF3
dbVarTAF3
ClinVarTAF3
MonarchTAF3
1000_GenomesTAF3 
Exome Variant ServerTAF3
GNOMAD BrowserENSG00000165632
Varsome BrowserTAF3
ACMGTAF3 variants
VarityQ5VWG9
Genomic Variants (DGV)TAF3 [DGVbeta]
DECIPHERTAF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF3 
Mutations
ICGC Data PortalTAF3 
TCGA Data PortalTAF3 
Broad Tumor PortalTAF3
OASIS PortalTAF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAF3
Mutations and Diseases : HGMDTAF3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAF3
DgiDB (Drug Gene Interaction Database)TAF3
DoCM (Curated mutations)TAF3
CIViC (Clinical Interpretations of Variants in Cancer)TAF3
Cancer3DTAF3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606576   
Orphanet
DisGeNETTAF3
MedgenTAF3
Genetic Testing Registry TAF3
NextProtQ5VWG9 [Medical]
GENETestsTAF3
Target ValidationTAF3
Huge Navigator TAF3 [HugePedia]
ClinGenTAF3
Clinical trials, drugs, therapy
MyCancerGenomeTAF3
Protein Interactions : CTDTAF3
Pharm GKB GenePA38222
PharosQ5VWG9
Clinical trialTAF3
Miscellaneous
canSAR (ICR)TAF3
HarmonizomeTAF3
DataMed IndexTAF3
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:24:47 CEST 2021

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