Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TAF4 (TATA-box binding protein associated factor 4)

Identity

Alias (NCBI)TAF(II)130
TAF(II)135
TAF2C
TAF2C1
TAF4A
TAFII-130
TAFII-135
TAFII130
TAFII135
HGNC (Hugo) TAF4
HGNC Alias symbTAFII130
TAFII135
HGNC Previous nameTAF4A
 TAF2C1
 TAF2C
HGNC Previous nameTATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD
 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
LocusID (NCBI) 6874
Atlas_Id 54682
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 61974798 and ends at 62065810 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PLCG1 (20q12) / TAF4 (20q13.33)SS18L1 (20q13.33) / TAF4 (20q13.33)TAF4 (20q13.33) / ALG10B (12q12)
TAF4 (20q13.33) / B4GALT5 (20q13.13)TAF4 (20q13.33) / BRIP1 (17q23.2)TAF4 (20q13.33) / CDH4 (20q13.33)
TAF4 (20q13.33) / FAF1 (1p32.3)TAF4 (20q13.33) / HHLA2 (3q13.13)TAF4 (20q13.33) / LAMA5 (20q13.33)
TAF4 (20q13.33) / LSM14B (20q13.33)TAF4 (20q13.33) / PSMA7 (20q13.33)TAF4 (20q13.33) / TAF4 (20q13.33)
TAF4 (20q13.33) / TCFL5 (20q13.33)TAF4 (20q13.33) / TSHZ2 (20q13.2)VAMP2 (17p13.1) / TAF4 (20q13.33)
PLCG1 20q12 / TAF4 20q13.33TAF4 20q13.33 / B4GALT5 20q13.13TAF4 20q13.33 / CDH4 20q13.33
TAF4 20q13.33 / FAF1 1p32.3TAF4 20q13.33 / LAMA5 20q13.33TAF4 20q13.33 / TCFL5 20q13.33
TAF4 20q13.33 / TSHZ2 20q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAF4   11537
Cards
Entrez_Gene (NCBI)TAF4    TATA-box binding protein associated factor 4
AliasesTAF(II)130; TAF(II)135; TAF2C; TAF2C1; 
TAF4A; TAFII-130; TAFII-135; TAFII130; TAFII135
GeneCards (Weizmann)TAF4
Ensembl hg19 (Hinxton)ENSG00000130699 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130699 [Gene_View]  ENSG00000130699 [Sequence]  chr20:61974798-62065810 [Contig_View]  TAF4 [Vega]
ICGC DataPortalENSG00000130699
TCGA cBioPortalTAF4
AceView (NCBI)TAF4
Genatlas (Paris)TAF4
SOURCE (Princeton)TAF4
Genetics Home Reference (NIH)TAF4
Genomic and cartography
GoldenPath hg38 (UCSC)TAF4  -     chr20:61974798-62065810 -  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF4  -     20q13.33   [Description]    (hg19-Feb_2009)
GoldenPathTAF4 - 20q13.33 [CytoView hg19]  TAF4 - 20q13.33 [CytoView hg38]
ImmunoBaseENSG00000130699
Genome Data Viewer NCBITAF4 [Mapview hg19]  
OMIM601796   
Gene and transcription
Genbank (Entrez)AK097744 AK123937 U75308 Y11354
RefSeq transcript (Entrez)NM_003185
Consensus coding sequences : CCDS (NCBI)TAF4
Gene ExpressionTAF4 [ NCBI-GEO ]   TAF4 [ EBI - ARRAY_EXPRESS ]   TAF4 [ SEEK ]   TAF4 [ MEM ]
Gene Expression Viewer (FireBrowse)TAF4 [ Firebrowse - Broad ]
GenevisibleExpression of TAF4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6874
GTEX Portal (Tissue expression)TAF4
Human Protein AtlasENSG00000130699-TAF4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00268   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00268  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00268
PhosPhoSitePlusO00268
Domaine pattern : Prosite (Expaxy)TAFH (PS51119)   
Domains : Interpro (EBI)Histone-fold    TAF4    TAFH/NHR1_dom_sf    TAFH_NHR1   
Domain families : Pfam (Sanger)TAF4 (PF05236)    TAFH (PF07531)   
Domain families : Pfam (NCBI)pfam05236    pfam07531   
Domain families : Smart (EMBL)TAFH (SM00549)  
Conserved Domain (NCBI)TAF4
PDB (RSDB)1H3O    2P6V    6MZC    6MZD    6MZL    6MZM   
PDB Europe1H3O    2P6V    6MZC    6MZD    6MZL    6MZM   
PDB (PDBSum)1H3O    2P6V    6MZC    6MZD    6MZL    6MZM   
PDB (IMB)1H3O    2P6V    6MZC    6MZD    6MZL    6MZM   
Structural Biology KnowledgeBase1H3O    2P6V    6MZC    6MZD    6MZL    6MZM   
SCOP (Structural Classification of Proteins)1H3O    2P6V    6MZC    6MZD    6MZL    6MZM   
CATH (Classification of proteins structures)1H3O    2P6V    6MZC    6MZD    6MZL    6MZM   
SuperfamilyO00268
AlphaFold pdb e-kbO00268   
Human Protein Atlas [tissue]ENSG00000130699-TAF4 [tissue]
HPRD11797
Protein Interaction databases
DIP (DOE-UCLA)O00268
IntAct (EBI)O00268
BioGRIDTAF4
STRING (EMBL)TAF4
ZODIACTAF4
Ontologies - Pathways
QuickGOO00268
Ontology : AmiGOchromatin  core promoter sequence-specific DNA binding  ovarian follicle development  DNA binding  protein binding  nucleoplasm  nucleoplasm  transcription factor TFIID complex  transcription factor TFIID complex  cytosol  DNA-templated transcription, initiation  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  RNA polymerase II general transcription initiation factor activity  RNA polymerase II general transcription initiation factor activity  aryl hydrocarbon receptor binding  protein-containing complex  transcription factor TFTC complex  protein heterodimerization activity  MLL1 complex  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIchromatin  core promoter sequence-specific DNA binding  ovarian follicle development  DNA binding  protein binding  nucleoplasm  nucleoplasm  transcription factor TFIID complex  transcription factor TFIID complex  cytosol  DNA-templated transcription, initiation  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  RNA polymerase II general transcription initiation factor activity  RNA polymerase II general transcription initiation factor activity  aryl hydrocarbon receptor binding  protein-containing complex  transcription factor TFTC complex  protein heterodimerization activity  MLL1 complex  regulation of signal transduction by p53 class mediator  
Pathways : KEGGBasal transcription factors    Huntington's disease    Herpes simplex infection   
NDEx NetworkTAF4
Atlas of Cancer Signalling NetworkTAF4
Wikipedia pathwaysTAF4
Orthology - Evolution
OrthoDB6874
GeneTree (enSembl)ENSG00000130699
Phylogenetic Trees/Animal Genes : TreeFamTAF4
Homologs : HomoloGeneTAF4
Homology/Alignments : Family Browser (UCSC)TAF4
Gene fusions - Rearrangements
Fusion : MitelmanPLCG1/TAF4 [20q12/20q13.33]  
Fusion : MitelmanTAF4/ALG10B [20q13.33/12q12]  
Fusion : MitelmanTAF4/B4GALT5 [20q13.33/20q13.13]  
Fusion : MitelmanTAF4/BRIP1 [20q13.33/17q23.2]  
Fusion : MitelmanTAF4/CDH4 [20q13.33/20q13.33]  
Fusion : MitelmanTAF4/FAF1 [20q13.33/1p32.3]  
Fusion : MitelmanTAF4/LAMA5 [20q13.33/20q13.33]  
Fusion : MitelmanTAF4/TCFL5 [20q13.33/20q13.33]  
Fusion : MitelmanTAF4/TSHZ2 [20q13.33/20q13.2]  
Fusion : QuiverTAF4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF4
dbVarTAF4
ClinVarTAF4
MonarchTAF4
1000_GenomesTAF4 
Exome Variant ServerTAF4
GNOMAD BrowserENSG00000130699
Varsome BrowserTAF4
ACMGTAF4 variants
VarityO00268
Genomic Variants (DGV)TAF4 [DGVbeta]
DECIPHERTAF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF4 
Mutations
ICGC Data PortalTAF4 
TCGA Data PortalTAF4 
Broad Tumor PortalTAF4
OASIS PortalTAF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAF4
Mutations and Diseases : HGMDTAF4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAF4
DgiDB (Drug Gene Interaction Database)TAF4
DoCM (Curated mutations)TAF4
CIViC (Clinical Interpretations of Variants in Cancer)TAF4
Cancer3DTAF4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601796   
Orphanet
DisGeNETTAF4
MedgenTAF4
Genetic Testing Registry TAF4
NextProtO00268 [Medical]
GENETestsTAF4
Target ValidationTAF4
Huge Navigator TAF4 [HugePedia]
ClinGenTAF4
Clinical trials, drugs, therapy
MyCancerGenomeTAF4
Protein Interactions : CTDTAF4
Pharm GKB GenePA36312
PharosO00268
Clinical trialTAF4
Miscellaneous
canSAR (ICR)TAF4
HarmonizomeTAF4
DataMed IndexTAF4
Probes
Litterature
PubMed110 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:34:10 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.