Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TAF6L (TATA-box binding protein associated factor 6 like)

Identity

Alias_namesTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65 kD
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
Alias_symbol (synonym)PAF65A
Other alias
HGNC (Hugo) TAF6L
LocusID (NCBI) 10629
Atlas_Id 42464
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62771303 and ends at 62787341 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TAF6L (11q12.3) / GLYATL1 (11q12.1)TAF6L (11q12.3) / PRKCI (3q26.2)TMEM179B (11q12.3) / TAF6L (11q12.3)
TAF6L 11q12.3 / GLYATL1 11q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAF6L   17305
Cards
Entrez_Gene (NCBI)TAF6L  10629  TATA-box binding protein associated factor 6 like
AliasesPAF65A
GeneCards (Weizmann)TAF6L
Ensembl hg19 (Hinxton)ENSG00000162227 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162227 [Gene_View]  chr11:62771303-62787341 [Contig_View]  TAF6L [Vega]
ICGC DataPortalENSG00000162227
TCGA cBioPortalTAF6L
AceView (NCBI)TAF6L
Genatlas (Paris)TAF6L
WikiGenes10629
SOURCE (Princeton)TAF6L
Genetics Home Reference (NIH)TAF6L
Genomic and cartography
GoldenPath hg38 (UCSC)TAF6L  -     chr11:62771303-62787341 +  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF6L  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblTAF6L - 11q12.3 [CytoView hg19]  TAF6L - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBITAF6L [Mapview hg19]  TAF6L [Mapview hg38]
OMIM602946   
Gene and transcription
Genbank (Entrez)AF069735 AK289499 AK301145 AK310054 AK314330
RefSeq transcript (Entrez)NM_006473
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAF6L
Cluster EST : UnigeneHs.714400 [ NCBI ]
CGAP (NCI)Hs.714400
Alternative Splicing GalleryENSG00000162227
Gene ExpressionTAF6L [ NCBI-GEO ]   TAF6L [ EBI - ARRAY_EXPRESS ]   TAF6L [ SEEK ]   TAF6L [ MEM ]
Gene Expression Viewer (FireBrowse)TAF6L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10629
GTEX Portal (Tissue expression)TAF6L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6J9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6J9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6J9
Splice isoforms : SwissVarQ9Y6J9
PhosPhoSitePlusQ9Y6J9
Domains : Interpro (EBI)Histone-fold    TAF6_C    TAF_TATA-bd   
Domain families : Pfam (Sanger)TAF (PF02969)    TAF6_C (PF07571)   
Domain families : Pfam (NCBI)pfam02969    pfam07571   
Domain families : Smart (EMBL)TAF (SM00803)  
Conserved Domain (NCBI)TAF6L
DMDM Disease mutations10629
Blocks (Seattle)TAF6L
SuperfamilyQ9Y6J9
Human Protein AtlasENSG00000162227
Peptide AtlasQ9Y6J9
HPRD04253
IPIIPI00007957   IPI00977820   IPI00976826   IPI00983560   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6J9
IntAct (EBI)Q9Y6J9
FunCoupENSG00000162227
BioGRIDTAF6L
STRING (EMBL)TAF6L
ZODIACTAF6L
Ontologies - Pathways
QuickGOQ9Y6J9
Ontology : AmiGOhistone deacetylase complex  DNA binding  transcription coactivator activity  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  chromatin remodeling  DNA-templated transcription, initiation  regulation of transcription from RNA polymerase II promoter  STAGA complex  histone H3 acetylation  protein heterodimerization activity  regulation of sequence-specific DNA binding transcription factor activity  extracellular exosome  
Ontology : EGO-EBIhistone deacetylase complex  DNA binding  transcription coactivator activity  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  chromatin remodeling  DNA-templated transcription, initiation  regulation of transcription from RNA polymerase II promoter  STAGA complex  histone H3 acetylation  protein heterodimerization activity  regulation of sequence-specific DNA binding transcription factor activity  extracellular exosome  
Pathways : KEGGBasal transcription factors    Herpes simplex infection   
NDEx NetworkTAF6L
Atlas of Cancer Signalling NetworkTAF6L
Wikipedia pathwaysTAF6L
Orthology - Evolution
OrthoDB10629
GeneTree (enSembl)ENSG00000162227
Phylogenetic Trees/Animal Genes : TreeFamTAF6L
HOVERGENQ9Y6J9
HOGENOMQ9Y6J9
Homologs : HomoloGeneTAF6L
Homology/Alignments : Family Browser (UCSC)TAF6L
Gene fusions - Rearrangements
Fusion : MitelmanTAF6L/GLYATL1 [11q12.3/11q12.1]  
Fusion: TCGATAF6L 11q12.3 GLYATL1 11q12.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF6L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF6L
dbVarTAF6L
ClinVarTAF6L
1000_GenomesTAF6L 
Exome Variant ServerTAF6L
ExAC (Exome Aggregation Consortium)TAF6L (select the gene name)
Genetic variants : HAPMAP10629
Genomic Variants (DGV)TAF6L [DGVbeta]
DECIPHERTAF6L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF6L 
Mutations
ICGC Data PortalTAF6L 
TCGA Data PortalTAF6L 
Broad Tumor PortalTAF6L
OASIS PortalTAF6L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF6L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAF6L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAF6L
DgiDB (Drug Gene Interaction Database)TAF6L
DoCM (Curated mutations)TAF6L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAF6L (select a term)
intoGenTAF6L
Cancer3DTAF6L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602946   
Orphanet
MedgenTAF6L
Genetic Testing Registry TAF6L
NextProtQ9Y6J9 [Medical]
TSGene10629
GENETestsTAF6L
Target ValidationTAF6L
Huge Navigator TAF6L [HugePedia]
snp3D : Map Gene to Disease10629
BioCentury BCIQTAF6L
ClinGenTAF6L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10629
Chemical/Pharm GKB GenePA38224
Clinical trialTAF6L
Miscellaneous
canSAR (ICR)TAF6L (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAF6L
EVEXTAF6L
GoPubMedTAF6L
iHOPTAF6L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:16:21 CEST 2017

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