Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TAF7 (TATA-box binding protein associated factor 7)

Identity

Alias_namesTAF2F
TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
Alias_symbol (synonym)TAFII55
Other alias
HGNC (Hugo) TAF7
LocusID (NCBI) 6879
Atlas_Id 42465
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 141318490 and ends at 141320784 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LARP1B (4q28.2) / TAF7 (5q31.3)TAF7 (5q31.3) / CYFIP2 (5q33.3)TAF7 (5q31.3) / EPC2 (2q23.1)
TAF7 (5q31.3) / TAF7 (5q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TAF7   11541
Cards
Entrez_Gene (NCBI)TAF7  6879  TATA-box binding protein associated factor 7
AliasesTAF2F; TAFII55
GeneCards (Weizmann)TAF7
Ensembl hg19 (Hinxton)ENSG00000178913 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178913 [Gene_View]  chr5:141318490-141320784 [Contig_View]  TAF7 [Vega]
ICGC DataPortalENSG00000178913
TCGA cBioPortalTAF7
AceView (NCBI)TAF7
Genatlas (Paris)TAF7
WikiGenes6879
SOURCE (Princeton)TAF7
Genetics Home Reference (NIH)TAF7
Genomic and cartography
GoldenPath hg38 (UCSC)TAF7  -     chr5:141318490-141320784 -  5q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF7  -     5q31.3   [Description]    (hg19-Feb_2009)
EnsemblTAF7 - 5q31.3 [CytoView hg19]  TAF7 - 5q31.3 [CytoView hg38]
Mapping of homologs : NCBITAF7 [Mapview hg19]  TAF7 [Mapview hg38]
OMIM600573   
Gene and transcription
Genbank (Entrez)AK314837 BC013397 BC022798 BC032737 U18062
RefSeq transcript (Entrez)NM_005642
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAF7
Cluster EST : UnigeneHs.438838 [ NCBI ]
CGAP (NCI)Hs.438838
Alternative Splicing GalleryENSG00000178913
Gene ExpressionTAF7 [ NCBI-GEO ]   TAF7 [ EBI - ARRAY_EXPRESS ]   TAF7 [ SEEK ]   TAF7 [ MEM ]
Gene Expression Viewer (FireBrowse)TAF7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6879
GTEX Portal (Tissue expression)TAF7
Human Protein AtlasENSG00000178913-TAF7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15545   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15545  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15545
Splice isoforms : SwissVarQ15545
PhosPhoSitePlusQ15545
Domains : Interpro (EBI)TAFII55_prot_cons_reg   
Domain families : Pfam (Sanger)TAFII55_N (PF04658)   
Domain families : Pfam (NCBI)pfam04658   
Domain families : Smart (EMBL)TAFII55_N (SM01370)  
Conserved Domain (NCBI)TAF7
DMDM Disease mutations6879
Blocks (Seattle)TAF7
PDB (SRS)4RGW    5FUR   
PDB (PDBSum)4RGW    5FUR   
PDB (IMB)4RGW    5FUR   
PDB (RSDB)4RGW    5FUR   
Structural Biology KnowledgeBase4RGW    5FUR   
SCOP (Structural Classification of Proteins)4RGW    5FUR   
CATH (Classification of proteins structures)4RGW    5FUR   
SuperfamilyQ15545
Human Protein Atlas [tissue]ENSG00000178913-TAF7 [tissue]
Peptide AtlasQ15545
HPRD07196
IPIIPI00018111   IPI00815699   
Protein Interaction databases
DIP (DOE-UCLA)Q15545
IntAct (EBI)Q15545
FunCoupENSG00000178913
BioGRIDTAF7
STRING (EMBL)TAF7
ZODIACTAF7
Ontologies - Pathways
QuickGOQ15545
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  spermine transport  DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleoplasm  nucleoplasm  transcription factor complex  transcription factor TFIID complex  transcription factor TFIID complex  Golgi apparatus  DNA-templated transcription, initiation  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  negative regulation of protein kinase activity  cyclin/CDK positive transcription elongation factor complex  transcription factor binding  intracellular estrogen receptor signaling pathway  transcription factor TFTC complex  histone acetyltransferase binding  negative regulation of histone acetylation  vitamin D receptor binding  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  thyroid hormone receptor binding  protein heterodimerization activity  RNA polymerase II transcriptional preinitiation complex assembly  regulation of transcription initiation from RNA polymerase II promoter  H3K27me3 modified histone binding  MLL1 complex  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  spermine transport  DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleoplasm  nucleoplasm  transcription factor complex  transcription factor TFIID complex  transcription factor TFIID complex  Golgi apparatus  DNA-templated transcription, initiation  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  negative regulation of protein kinase activity  cyclin/CDK positive transcription elongation factor complex  transcription factor binding  intracellular estrogen receptor signaling pathway  transcription factor TFTC complex  histone acetyltransferase binding  negative regulation of histone acetylation  vitamin D receptor binding  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  thyroid hormone receptor binding  protein heterodimerization activity  RNA polymerase II transcriptional preinitiation complex assembly  regulation of transcription initiation from RNA polymerase II promoter  H3K27me3 modified histone binding  MLL1 complex  regulation of signal transduction by p53 class mediator  
Pathways : KEGGBasal transcription factors   
NDEx NetworkTAF7
Atlas of Cancer Signalling NetworkTAF7
Wikipedia pathwaysTAF7
Orthology - Evolution
OrthoDB6879
GeneTree (enSembl)ENSG00000178913
Phylogenetic Trees/Animal Genes : TreeFamTAF7
HOVERGENQ15545
HOGENOMQ15545
Homologs : HomoloGeneTAF7
Homology/Alignments : Family Browser (UCSC)TAF7
Gene fusions - Rearrangements
Fusion : QuiverTAF7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF7
dbVarTAF7
ClinVarTAF7
1000_GenomesTAF7 
Exome Variant ServerTAF7
ExAC (Exome Aggregation Consortium)ENSG00000178913
GNOMAD BrowserENSG00000178913
Genetic variants : HAPMAP6879
Genomic Variants (DGV)TAF7 [DGVbeta]
DECIPHERTAF7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF7 
Mutations
ICGC Data PortalTAF7 
TCGA Data PortalTAF7 
Broad Tumor PortalTAF7
OASIS PortalTAF7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAF7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAF7
DgiDB (Drug Gene Interaction Database)TAF7
DoCM (Curated mutations)TAF7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAF7 (select a term)
intoGenTAF7
Cancer3DTAF7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600573   
Orphanet
DisGeNETTAF7
MedgenTAF7
Genetic Testing Registry TAF7
NextProtQ15545 [Medical]
TSGene6879
GENETestsTAF7
Target ValidationTAF7
Huge Navigator TAF7 [HugePedia]
snp3D : Map Gene to Disease6879
BioCentury BCIQTAF7
ClinGenTAF7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6879
Chemical/Pharm GKB GenePA36316
Clinical trialTAF7
Miscellaneous
canSAR (ICR)TAF7 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAF7
EVEXTAF7
GoPubMedTAF7
iHOPTAF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 28 13:40:43 CET 2018
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