Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TAF7 (TATA-box binding protein associated factor 7)

Identity

Alias (NCBI)TAF2F
TAFII55
HGNC (Hugo) TAF7
HGNC Alias symbTAFII55
HGNC Previous nameTAF2F
HGNC Previous nameTATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD
 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
LocusID (NCBI) 6879
Atlas_Id 42465
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 141318490 and ends at 141320784 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LARP1B (4q28.2) / TAF7 (5q31.3)TAF7 (5q31.3) / CYFIP2 (5q33.3)TAF7 (5q31.3) / EPC2 (2q23.1)
TAF7 (5q31.3) / TAF7 (5q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)TAF7   11541
Cards
Entrez_Gene (NCBI)TAF7    TATA-box binding protein associated factor 7
AliasesTAF2F; TAFII55
GeneCards (Weizmann)TAF7
Ensembl hg19 (Hinxton)ENSG00000178913 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178913 [Gene_View]  ENSG00000178913 [Sequence]  chr5:141318490-141320784 [Contig_View]  TAF7 [Vega]
ICGC DataPortalENSG00000178913
TCGA cBioPortalTAF7
AceView (NCBI)TAF7
Genatlas (Paris)TAF7
SOURCE (Princeton)TAF7
Genetics Home Reference (NIH)TAF7
Genomic and cartography
GoldenPath hg38 (UCSC)TAF7  -     chr5:141318490-141320784 -  5q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF7  -     5q31.3   [Description]    (hg19-Feb_2009)
GoldenPathTAF7 - 5q31.3 [CytoView hg19]  TAF7 - 5q31.3 [CytoView hg38]
ImmunoBaseENSG00000178913
Genome Data Viewer NCBITAF7 [Mapview hg19]  
OMIM600573   
Gene and transcription
Genbank (Entrez)AK314837 BC013397 BC022798 BC032737 U18062
RefSeq transcript (Entrez)NM_005642
Consensus coding sequences : CCDS (NCBI)TAF7
Gene ExpressionTAF7 [ NCBI-GEO ]   TAF7 [ EBI - ARRAY_EXPRESS ]   TAF7 [ SEEK ]   TAF7 [ MEM ]
Gene Expression Viewer (FireBrowse)TAF7 [ Firebrowse - Broad ]
GenevisibleExpression of TAF7 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6879
GTEX Portal (Tissue expression)TAF7
Human Protein AtlasENSG00000178913-TAF7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15545   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15545  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15545
PhosPhoSitePlusQ15545
Domains : Interpro (EBI)TAF7    TAFII55_prot_cons_reg   
Domain families : Pfam (Sanger)TAFII55_N (PF04658)   
Domain families : Pfam (NCBI)pfam04658   
Domain families : Smart (EMBL)TAFII55_N (SM01370)  
Conserved Domain (NCBI)TAF7
PDB (RSDB)4RGW    5FUR    6MZL    6MZM   
PDB Europe4RGW    5FUR    6MZL    6MZM   
PDB (PDBSum)4RGW    5FUR    6MZL    6MZM   
PDB (IMB)4RGW    5FUR    6MZL    6MZM   
Structural Biology KnowledgeBase4RGW    5FUR    6MZL    6MZM   
SCOP (Structural Classification of Proteins)4RGW    5FUR    6MZL    6MZM   
CATH (Classification of proteins structures)4RGW    5FUR    6MZL    6MZM   
SuperfamilyQ15545
AlphaFold pdb e-kbQ15545   
Human Protein Atlas [tissue]ENSG00000178913-TAF7 [tissue]
HPRD07196
Protein Interaction databases
DIP (DOE-UCLA)Q15545
IntAct (EBI)Q15545
BioGRIDTAF7
STRING (EMBL)TAF7
ZODIACTAF7
Ontologies - Pathways
QuickGOQ15545
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  spermine transport  transcription cis-regulatory region binding  TFIIH-class transcription factor complex binding  protein binding  nucleoplasm  transcription regulator complex  transcription factor TFIID complex  transcription factor TFIID complex  cytoplasm  DNA-templated transcription, initiation  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  negative regulation of protein kinase activity  transcription factor binding  RNA polymerase II general transcription initiation factor activity  RNA polymerase II general transcription initiation factor activity  RNA polymerase II general transcription initiation factor activity  intracellular estrogen receptor signaling pathway  transcription factor TFTC complex  histone acetyltransferase binding  negative regulation of histone acetylation  vitamin D receptor binding  negative regulation of MHC class I biosynthetic process  negative regulation of MHC class II biosynthetic process  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  thyroid hormone receptor binding  protein heterodimerization activity  RNA polymerase II preinitiation complex assembly  H3K27me3 modified histone binding  MLL1 complex  negative regulation of histone H4 acetylation  P-TEFb complex binding  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  spermine transport  transcription cis-regulatory region binding  TFIIH-class transcription factor complex binding  protein binding  nucleoplasm  transcription regulator complex  transcription factor TFIID complex  transcription factor TFIID complex  cytoplasm  DNA-templated transcription, initiation  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  negative regulation of protein kinase activity  transcription factor binding  RNA polymerase II general transcription initiation factor activity  RNA polymerase II general transcription initiation factor activity  RNA polymerase II general transcription initiation factor activity  intracellular estrogen receptor signaling pathway  transcription factor TFTC complex  histone acetyltransferase binding  negative regulation of histone acetylation  vitamin D receptor binding  negative regulation of MHC class I biosynthetic process  negative regulation of MHC class II biosynthetic process  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  thyroid hormone receptor binding  protein heterodimerization activity  RNA polymerase II preinitiation complex assembly  H3K27me3 modified histone binding  MLL1 complex  negative regulation of histone H4 acetylation  P-TEFb complex binding  regulation of signal transduction by p53 class mediator  
Pathways : KEGGBasal transcription factors   
NDEx NetworkTAF7
Atlas of Cancer Signalling NetworkTAF7
Wikipedia pathwaysTAF7
Orthology - Evolution
OrthoDB6879
GeneTree (enSembl)ENSG00000178913
Phylogenetic Trees/Animal Genes : TreeFamTAF7
Homologs : HomoloGeneTAF7
Homology/Alignments : Family Browser (UCSC)TAF7
Gene fusions - Rearrangements
Fusion : QuiverTAF7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF7
dbVarTAF7
ClinVarTAF7
MonarchTAF7
1000_GenomesTAF7 
Exome Variant ServerTAF7
GNOMAD BrowserENSG00000178913
Varsome BrowserTAF7
ACMGTAF7 variants
VarityQ15545
Genomic Variants (DGV)TAF7 [DGVbeta]
DECIPHERTAF7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF7 
Mutations
ICGC Data PortalTAF7 
TCGA Data PortalTAF7 
Broad Tumor PortalTAF7
OASIS PortalTAF7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAF7
Mutations and Diseases : HGMDTAF7
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAF7
DgiDB (Drug Gene Interaction Database)TAF7
DoCM (Curated mutations)TAF7
CIViC (Clinical Interpretations of Variants in Cancer)TAF7
Cancer3DTAF7
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600573   
Orphanet
DisGeNETTAF7
MedgenTAF7
Genetic Testing Registry TAF7
NextProtQ15545 [Medical]
GENETestsTAF7
Target ValidationTAF7
Huge Navigator TAF7 [HugePedia]
ClinGenTAF7
Clinical trials, drugs, therapy
MyCancerGenomeTAF7
Protein Interactions : CTDTAF7
Pharm GKB GenePA36316
PharosQ15545
Clinical trialTAF7
Miscellaneous
canSAR (ICR)TAF7
HarmonizomeTAF7
DataMed IndexTAF7
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:11 CEST 2021
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