Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TAF7L (TATA-box binding protein associated factor 7 like)

Identity

Alias_namesTAF2Q
TATA box binding protein (TBP)-associated factor, RNA polymerase II, Q
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
Alias_symbol (synonym)CT40
Other alias
HGNC (Hugo) TAF7L
LocusID (NCBI) 54457
Atlas_Id 53489
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at 101268253 and ends at 101293071 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
UNC13B (9p13.3) / TAF7L (Xq22.1)UNC13B 9p13.3 / TAF7L Xq22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(X;9)(q22;p13) UNC13B/TAF7L


External links

Nomenclature
HGNC (Hugo)TAF7L   11548
Cards
Entrez_Gene (NCBI)TAF7L  54457  TATA-box binding protein associated factor 7 like
AliasesCT40; TAF2Q
GeneCards (Weizmann)TAF7L
Ensembl hg19 (Hinxton)ENSG00000102387 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102387 [Gene_View]  ENSG00000102387 [Sequence]  chrX:101268253-101293071 [Contig_View]  TAF7L [Vega]
ICGC DataPortalENSG00000102387
TCGA cBioPortalTAF7L
AceView (NCBI)TAF7L
Genatlas (Paris)TAF7L
WikiGenes54457
SOURCE (Princeton)TAF7L
Genetics Home Reference (NIH)TAF7L
Genomic and cartography
GoldenPath hg38 (UCSC)TAF7L  -     chrX:101268253-101293071 -  Xq22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF7L  -     Xq22.1   [Description]    (hg19-Feb_2009)
EnsemblTAF7L - Xq22.1 [CytoView hg19]  TAF7L - Xq22.1 [CytoView hg38]
Mapping of homologs : NCBITAF7L [Mapview hg19]  TAF7L [Mapview hg38]
OMIM300314   
Gene and transcription
Genbank (Entrez)AF285595 AK026810 AK308261 BC043391 DB042169
RefSeq transcript (Entrez)NM_001168474 NM_024885
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAF7L
Cluster EST : UnigeneHs.223806 [ NCBI ]
CGAP (NCI)Hs.223806
Alternative Splicing GalleryENSG00000102387
Gene ExpressionTAF7L [ NCBI-GEO ]   TAF7L [ EBI - ARRAY_EXPRESS ]   TAF7L [ SEEK ]   TAF7L [ MEM ]
Gene Expression Viewer (FireBrowse)TAF7L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54457
GTEX Portal (Tissue expression)TAF7L
Human Protein AtlasENSG00000102387-TAF7L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5H9L4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5H9L4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5H9L4
Splice isoforms : SwissVarQ5H9L4
PhosPhoSitePlusQ5H9L4
Domains : Interpro (EBI)TAF7    TAFII55_prot_cons_reg   
Domain families : Pfam (Sanger)TAFII55_N (PF04658)   
Domain families : Pfam (NCBI)pfam04658   
Domain families : Smart (EMBL)TAFII55_N (SM01370)  
Conserved Domain (NCBI)TAF7L
DMDM Disease mutations54457
Blocks (Seattle)TAF7L
SuperfamilyQ5H9L4
Human Protein Atlas [tissue]ENSG00000102387-TAF7L [tissue]
Peptide AtlasQ5H9L4
HPRD02259
IPIIPI00329227   IPI00478059   IPI00016459   
Protein Interaction databases
DIP (DOE-UCLA)Q5H9L4
IntAct (EBI)Q5H9L4
FunCoupENSG00000102387
BioGRIDTAF7L
STRING (EMBL)TAF7L
ZODIACTAF7L
Ontologies - Pathways
QuickGOQ5H9L4
Ontology : AmiGOmolecular_function  transcription coactivator activity  transcription factor TFIID complex  cytoplasm  regulation of transcription by RNA polymerase II  multicellular organism development  spermatogenesis  transcription factor binding  biological_process  cell differentiation  histone acetyltransferase binding  transcription regulatory region DNA binding  RNA polymerase II transcriptional preinitiation complex assembly  positive regulation of nucleic acid-templated transcription  
Ontology : EGO-EBImolecular_function  transcription coactivator activity  transcription factor TFIID complex  cytoplasm  regulation of transcription by RNA polymerase II  multicellular organism development  spermatogenesis  transcription factor binding  biological_process  cell differentiation  histone acetyltransferase binding  transcription regulatory region DNA binding  RNA polymerase II transcriptional preinitiation complex assembly  positive regulation of nucleic acid-templated transcription  
Pathways : KEGGBasal transcription factors   
NDEx NetworkTAF7L
Atlas of Cancer Signalling NetworkTAF7L
Wikipedia pathwaysTAF7L
Orthology - Evolution
OrthoDB54457
GeneTree (enSembl)ENSG00000102387
Phylogenetic Trees/Animal Genes : TreeFamTAF7L
HOVERGENQ5H9L4
HOGENOMQ5H9L4
Homologs : HomoloGeneTAF7L
Homology/Alignments : Family Browser (UCSC)TAF7L
Gene fusions - Rearrangements
Fusion : MitelmanUNC13B/TAF7L [9p13.3/Xq22.1]  [t(X;9)(q22;p13)]  
Fusion PortalUNC13B 9p13.3 TAF7L Xq22.1 LUAD
Fusion : QuiverTAF7L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF7L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF7L
dbVarTAF7L
ClinVarTAF7L
1000_GenomesTAF7L 
Exome Variant ServerTAF7L
ExAC (Exome Aggregation Consortium)ENSG00000102387
GNOMAD BrowserENSG00000102387
Varsome BrowserTAF7L
Genetic variants : HAPMAP54457
Genomic Variants (DGV)TAF7L [DGVbeta]
DECIPHERTAF7L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF7L 
Mutations
ICGC Data PortalTAF7L 
TCGA Data PortalTAF7L 
Broad Tumor PortalTAF7L
OASIS PortalTAF7L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF7L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAF7L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch TAF7L
DgiDB (Drug Gene Interaction Database)TAF7L
DoCM (Curated mutations)TAF7L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAF7L (select a term)
intoGenTAF7L
Cancer3DTAF7L(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300314   
Orphanet
DisGeNETTAF7L
MedgenTAF7L
Genetic Testing Registry TAF7L
NextProtQ5H9L4 [Medical]
TSGene54457
GENETestsTAF7L
Target ValidationTAF7L
Huge Navigator TAF7L [HugePedia]
snp3D : Map Gene to Disease54457
BioCentury BCIQTAF7L
ClinGenTAF7L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54457
Chemical/Pharm GKB GenePA36323
Clinical trialTAF7L
Miscellaneous
canSAR (ICR)TAF7L (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAF7L
EVEXTAF7L
GoPubMedTAF7L
iHOPTAF7L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:56:17 CEST 2018

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