TAF9 (TATA-box binding protein associated factor 9)

2003-05-01  

Identity

HGNC
LOCATION
5q13.2
LOCUSID
ALIAS
MGC:5067,STAF31/32,TAF2G,TAFII-31,TAFII-32,TAFII31,TAFII32,TAFIID32

Other Information

Locus ID:

NCBI: 6880
MIM: 600822
HGNC: 11542
Ensembl: ENSG00000273841

Variants:

dbSNP: 6880
ClinVar: 6880
TCGA: ENSG00000273841
COSMIC: TAF9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000273841ENST00000217893Q16594
ENSG00000273841ENST00000328663Q16594
ENSG00000273841ENST00000503245D6RIE8
ENSG00000273841ENST00000504109D6RGK3
ENSG00000273841ENST00000506736Q16594
ENSG00000273841ENST00000508954D6RHW1
ENSG00000273841ENST00000509462D6RIV9
ENSG00000273841ENST00000512152D6RIY1

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through PhosphorylationREACTOMER-HSA-6804756
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
154892272004Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription.131
179678942008STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.38
156018432005Core promoter binding by histone-like TAF complexes.33
192516492009Distinct modes of gene regulation by a cell-specific transcriptional activator.19
226962182012TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.13
128377532003In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.11
196430372009Multiple hTAF(II)31-binding motifs in the intrinsically unfolded transcriptional activation domain of VP16.9
262821812015p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.9
292572972018Cancer‑testis antigen HCA587/MAGEC2 interacts with the general transcription coactivator TAF9 in cancer cells.0

Citation

Dessen P

TAF9 (TATA-box binding protein associated factor 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42466/taf9