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TANC1 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1)

Identity

Alias_symbol (synonym)KIAA1728
ROLSB
Other aliasTANC
HGNC (Hugo) TANC1
LocusID (NCBI) 85461
Atlas_Id 54684
Location 2q24.2  [Link to chromosome band 2q24]
Location_base_pair Starts at 158968634 and ends at 159232659 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PVR (19q13.31) / TANC1 (2q24.2)SH3RF2 (5q32) / TANC1 (2q24.2)SLC38A11 (2q24.3) / TANC1 (2q24.2)
TANC1 (2q24.2) / BTF3L4 (1p32.3)TANC1 (2q24.2) / CRLF1 (19p13.11)TANC1 (2q24.2) / MAML2 (11q21)
TANC1 (2q24.2) / MTMR4 (17q22)TANC1 (2q24.2) / NR4A2 (2q24.1)TANC1 (2q24.2) / PKP4 (2q24.1)
TANC1 (2q24.2) / SLC4A1AP (2p23.3)TANC1 (2q24.2) / TMEM2 (9q21.13)TANC1 (2q24.2) / VSIG10 (12q24.23)
TANC1 2q24.2 / NR4A2 2q24.1TANC1 2q24.2 / PKP4 2q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TANC1   29364
Cards
Entrez_Gene (NCBI)TANC1  85461  tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
AliasesROLSB; TANC
GeneCards (Weizmann)TANC1
Ensembl hg19 (Hinxton)ENSG00000115183 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115183 [Gene_View]  chr2:158968634-159232659 [Contig_View]  TANC1 [Vega]
ICGC DataPortalENSG00000115183
TCGA cBioPortalTANC1
AceView (NCBI)TANC1
Genatlas (Paris)TANC1
WikiGenes85461
SOURCE (Princeton)TANC1
Genetics Home Reference (NIH)TANC1
Genomic and cartography
GoldenPath hg38 (UCSC)TANC1  -     chr2:158968634-159232659 +  2q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TANC1  -     2q24.2   [Description]    (hg19-Feb_2009)
EnsemblTANC1 - 2q24.2 [CytoView hg19]  TANC1 - 2q24.2 [CytoView hg38]
Mapping of homologs : NCBITANC1 [Mapview hg19]  TANC1 [Mapview hg38]
OMIM611397   
Gene and transcription
Genbank (Entrez)AA773835 AB051515 AK000401 AK023422 AK094285
RefSeq transcript (Entrez)NM_001145909 NM_001350062 NM_001350063 NM_001350064 NM_001350065 NM_033394
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TANC1
Cluster EST : UnigeneHs.61590 [ NCBI ]
CGAP (NCI)Hs.61590
Alternative Splicing GalleryENSG00000115183
Gene ExpressionTANC1 [ NCBI-GEO ]   TANC1 [ EBI - ARRAY_EXPRESS ]   TANC1 [ SEEK ]   TANC1 [ MEM ]
Gene Expression Viewer (FireBrowse)TANC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85461
GTEX Portal (Tissue expression)TANC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0D5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C0D5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C0D5
Splice isoforms : SwissVarQ9C0D5
PhosPhoSitePlusQ9C0D5
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  TPR (SM00028)  
Conserved Domain (NCBI)TANC1
DMDM Disease mutations85461
Blocks (Seattle)TANC1
SuperfamilyQ9C0D5
Human Protein AtlasENSG00000115183
Peptide AtlasQ9C0D5
HPRD18146
IPIIPI00173946   IPI00885010   IPI00925894   IPI00983886   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0D5
IntAct (EBI)Q9C0D5
FunCoupENSG00000115183
BioGRIDTANC1
STRING (EMBL)TANC1
ZODIACTANC1
Ontologies - Pathways
QuickGOQ9C0D5
Ontology : AmiGOmyoblast fusion  visual learning  postsynaptic density  cell junction  dendrite  neuronal cell body  axon terminus  postsynaptic membrane  dendritic spine maintenance  
Ontology : EGO-EBImyoblast fusion  visual learning  postsynaptic density  cell junction  dendrite  neuronal cell body  axon terminus  postsynaptic membrane  dendritic spine maintenance  
NDEx NetworkTANC1
Atlas of Cancer Signalling NetworkTANC1
Wikipedia pathwaysTANC1
Orthology - Evolution
OrthoDB85461
GeneTree (enSembl)ENSG00000115183
Phylogenetic Trees/Animal Genes : TreeFamTANC1
HOVERGENQ9C0D5
HOGENOMQ9C0D5
Homologs : HomoloGeneTANC1
Homology/Alignments : Family Browser (UCSC)TANC1
Gene fusions - Rearrangements
Fusion : MitelmanTANC1/MTMR4 [2q24.2/17q22]  
Fusion : MitelmanTANC1/NR4A2 [2q24.2/2q24.1]  [t(2;2)(q24;q24)]  
Fusion : MitelmanTANC1/PKP4 [2q24.2/2q24.1]  [t(2;2)(q24;q24)]  
Fusion : MitelmanTANC1/SLC4A1AP [2q24.2/2p23.3]  [t(2;2)(p23;q24)]  
Fusion: TCGATANC1 2q24.2 NR4A2 2q24.1 LUAD
Fusion: TCGATANC1 2q24.2 PKP4 2q24.1 BRCA OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTANC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TANC1
dbVarTANC1
ClinVarTANC1
1000_GenomesTANC1 
Exome Variant ServerTANC1
ExAC (Exome Aggregation Consortium)TANC1 (select the gene name)
Genetic variants : HAPMAP85461
Genomic Variants (DGV)TANC1 [DGVbeta]
DECIPHERTANC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTANC1 
Mutations
ICGC Data PortalTANC1 
TCGA Data PortalTANC1 
Broad Tumor PortalTANC1
OASIS PortalTANC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTANC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTANC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TANC1
DgiDB (Drug Gene Interaction Database)TANC1
DoCM (Curated mutations)TANC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TANC1 (select a term)
intoGenTANC1
Cancer3DTANC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611397   
Orphanet
MedgenTANC1
Genetic Testing Registry TANC1
NextProtQ9C0D5 [Medical]
TSGene85461
GENETestsTANC1
Target ValidationTANC1
Huge Navigator TANC1 [HugePedia]
snp3D : Map Gene to Disease85461
BioCentury BCIQTANC1
ClinGenTANC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85461
Chemical/Pharm GKB GenePA142670838
Clinical trialTANC1
Miscellaneous
canSAR (ICR)TANC1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTANC1
EVEXTANC1
GoPubMedTANC1
iHOPTANC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:09:11 CEST 2017

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