Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TANGO2 (transport and golgi organization 2 homolog)

Identity

Alias_namesC22orf25
chromosome 22 open reading frame 25
transport and golgi organization 2 homolog (Drosophila)
Alias_symbol (synonym)DKFZp761P1121
Other aliasMECRCN
HGNC (Hugo) TANGO2
LocusID (NCBI) 128989
Atlas_Id 74477
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 20017000 and ends at 20067164 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACO2 (22q13.2) / TANGO2 (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(22;22)(q11;q13) ACO2/TANGO2

External links

Nomenclature
HGNC (Hugo)TANGO2   25439
Cards
Entrez_Gene (NCBI)TANGO2  128989  transport and golgi organization 2 homolog
AliasesC22orf25; MECRCN
GeneCards (Weizmann)TANGO2
Ensembl hg19 (Hinxton)ENSG00000183597 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183597 [Gene_View]  ENSG00000183597 [Sequence]  chr22:20017000-20067164 [Contig_View]  TANGO2 [Vega]
ICGC DataPortalENSG00000183597
TCGA cBioPortalTANGO2
AceView (NCBI)TANGO2
Genatlas (Paris)TANGO2
WikiGenes128989
SOURCE (Princeton)TANGO2
Genetics Home Reference (NIH)TANGO2
Genomic and cartography
GoldenPath hg38 (UCSC)TANGO2  -     chr22:20017000-20067164 +  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TANGO2  -     22q11.21   [Description]    (hg19-Feb_2009)
EnsemblTANGO2 - 22q11.21 [CytoView hg19]  TANGO2 - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBITANGO2 [Mapview hg19]  TANGO2 [Mapview hg38]
OMIM616830   616878   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TANGO2
Cluster EST : UnigeneHs.474233 [ NCBI ]
CGAP (NCI)Hs.474233
Alternative Splicing GalleryENSG00000183597
Gene ExpressionTANGO2 [ NCBI-GEO ]   TANGO2 [ EBI - ARRAY_EXPRESS ]   TANGO2 [ SEEK ]   TANGO2 [ MEM ]
Gene Expression Viewer (FireBrowse)TANGO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)128989
GTEX Portal (Tissue expression)TANGO2
Human Protein AtlasENSG00000183597-TANGO2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ICL3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ICL3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ICL3
Splice isoforms : SwissVarQ6ICL3
PhosPhoSitePlusQ6ICL3
Domains : Interpro (EBI)TANGO2   
Domain families : Pfam (Sanger)TANGO2 (PF05742)   
Domain families : Pfam (NCBI)pfam05742   
Conserved Domain (NCBI)TANGO2
DMDM Disease mutations128989
Blocks (Seattle)TANGO2
SuperfamilyQ6ICL3
Human Protein Atlas [tissue]ENSG00000183597-TANGO2 [tissue]
Peptide AtlasQ6ICL3
HPRD13229
IPIIPI00395547   IPI00168034   IPI00384646   IPI00880089   IPI01014937   IPI01013334   IPI00465023   IPI00878830   IPI00879566   IPI00878106   IPI00877810   IPI00878300   
Protein Interaction databases
DIP (DOE-UCLA)Q6ICL3
IntAct (EBI)Q6ICL3
FunCoupENSG00000183597
BioGRIDTANGO2
STRING (EMBL)TANGO2
ZODIACTANGO2
Ontologies - Pathways
QuickGOQ6ICL3
Ontology : AmiGOGolgi apparatus  
Ontology : EGO-EBIGolgi apparatus  
NDEx NetworkTANGO2
Atlas of Cancer Signalling NetworkTANGO2
Wikipedia pathwaysTANGO2
Orthology - Evolution
OrthoDB128989
GeneTree (enSembl)ENSG00000183597
Phylogenetic Trees/Animal Genes : TreeFamTANGO2
HOVERGENQ6ICL3
HOGENOMQ6ICL3
Homologs : HomoloGeneTANGO2
Homology/Alignments : Family Browser (UCSC)TANGO2
Gene fusions - Rearrangements
Fusion : QuiverTANGO2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTANGO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TANGO2
dbVarTANGO2
ClinVarTANGO2
1000_GenomesTANGO2 
Exome Variant ServerTANGO2
ExAC (Exome Aggregation Consortium)ENSG00000183597
GNOMAD BrowserENSG00000183597
Varsome BrowserTANGO2
Genetic variants : HAPMAP128989
Genomic Variants (DGV)TANGO2 [DGVbeta]
DECIPHERTANGO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTANGO2 
Mutations
ICGC Data PortalTANGO2 
TCGA Data PortalTANGO2 
Broad Tumor PortalTANGO2
OASIS PortalTANGO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTANGO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTANGO2
BioMutasearch TANGO2
DgiDB (Drug Gene Interaction Database)TANGO2
DoCM (Curated mutations)TANGO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TANGO2 (select a term)
intoGenTANGO2
Cancer3DTANGO2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616830    616878   
Orphanet
DisGeNETTANGO2
MedgenTANGO2
Genetic Testing Registry TANGO2
NextProtQ6ICL3 [Medical]
TSGene128989
GENETestsTANGO2
Target ValidationTANGO2
Huge Navigator TANGO2 [HugePedia]
snp3D : Map Gene to Disease128989
BioCentury BCIQTANGO2
ClinGenTANGO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD128989
Chemical/Pharm GKB GenePA143485406
Clinical trialTANGO2
Miscellaneous
canSAR (ICR)TANGO2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTANGO2
EVEXTANGO2
GoPubMedTANGO2
iHOPTANGO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:34:01 CEST 2018
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