TAP2 (transporter 2, ATP binding cassette subfamily B member)

2007-02-01  

Identity

HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
ABC18,ABCB3,APT2,D6S217E,PSF-2,PSF2,RING11
FUSION GENES

Other Information

Locus ID:

NCBI: 6891
MIM: 170261
HGNC: 44
Ensembl: ENSG00000204267

Variants:

dbSNP: 6891
ClinVar: 6891
TCGA: ENSG00000204267
COSMIC: TAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204267ENST00000374897Q03519
ENSG00000204267ENST00000374897Q5JNW1
ENSG00000204267ENST00000620123A0A087WYD6
ENSG00000204267ENST00000652259Q03519
ENSG00000204267ENST00000652259Q9UP03

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
ABC transportersKEGGko02010
Antigen processing and presentationKEGGko04612
Primary immunodeficiencyKEGGko05340
ABC transportersKEGGhsa02010
Antigen processing and presentationKEGGhsa04612
Primary immunodeficiencyKEGGhsa05340
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Herpes simplex infectionKEGGko05168
Herpes simplex infectionKEGGhsa05168
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen Presentation: Folding, assembly and peptide loading of class I MHCREACTOMER-HSA-983170
Antigen processing-Cross presentationREACTOMER-HSA-1236975
ER-Phagosome pathwayREACTOMER-HSA-1236974

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375231932024Regulatory Variants on the Leukocyte Immunoglobulin-Like Receptor Gene Cluster are Associated with Crohn's Disease and Interact with Regulatory Variants for TAP2.0
375231932024Regulatory Variants on the Leukocyte Immunoglobulin-Like Receptor Gene Cluster are Associated with Crohn's Disease and Interact with Regulatory Variants for TAP2.0
362274112023Delayed Diagnosis of Chronic Necrotizing Granulomatous Skin Lesions due to TAP2 Deficiency.3
362274112023Delayed Diagnosis of Chronic Necrotizing Granulomatous Skin Lesions due to TAP2 Deficiency.3
349734982022Spotlight on TAP and its vital role in antigen presentation and cross-presentation.21
354853662022Association study of TAP and HLA-I gene combination with chronic hepatitis C virus infection in a Han population in China.0
349734982022Spotlight on TAP and its vital role in antigen presentation and cross-presentation.21
354853662022Association study of TAP and HLA-I gene combination with chronic hepatitis C virus infection in a Han population in China.0
337367392021Associations of genetic variants at TAP1 and TAP2 with pulmonary tuberculosis risk among the Chinese population.6
340506052021Polymorphisms in transporter associated with antigen presenting are associated with cervical intraepithelial neoplasia and cervical cancer in a Chinese Han population.5
343731322021The association of TAP polymorphisms with non-small-cell lung cancer in the Han Chinese population.2
337367392021Associations of genetic variants at TAP1 and TAP2 with pulmonary tuberculosis risk among the Chinese population.6
340506052021Polymorphisms in transporter associated with antigen presenting are associated with cervical intraepithelial neoplasia and cervical cancer in a Chinese Han population.5
343731322021The association of TAP polymorphisms with non-small-cell lung cancer in the Han Chinese population.2
317328312020Analysis of transporter associated with antigen presentation (TAP) genes polymorphisms with HIV-1 infection.6

Citation

Dessen P

TAP2 (transporter 2, ATP binding cassette subfamily B member)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43829/tap2