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TAPBP (TAP binding protein (tapasin))

Identity

Alias_namesTAP binding protein (tapasin)
Alias_symbol (synonym)TAPA
Other aliasNGS17
TPN
TPSN
HGNC (Hugo) TAPBP
LocusID (NCBI) 6892
Atlas_Id 42470
Location 6p21.32  [Link to chromosome band 6p21]
Location_base_pair Starts at 33267472 and ends at 33282164 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CWF19L1 (10q24.31) / TAPBP (6p21.32)EEF2 (19p13.3) / TAPBP (6p21.32)INS-IGF2 (11p15.5) / TAPBP (6p21.32)
TAPBP (6p21.32) / DAXX (6p21.32)TRUB2 (9q34.11) / TAPBP (6p21.32)TAPBP 6p21.32 / DAXX 6p21.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAPBP   11566
LRG (Locus Reference Genomic)LRG_114
Cards
Entrez_Gene (NCBI)TAPBP  6892  TAP binding protein (tapasin)
AliasesNGS17; TAPA; TPN; TPSN
GeneCards (Weizmann)TAPBP
Ensembl hg19 (Hinxton)ENSG00000231925 [Gene_View]  chr6:33267472-33282164 [Contig_View]  TAPBP [Vega]
Ensembl hg38 (Hinxton)ENSG00000231925 [Gene_View]  chr6:33267472-33282164 [Contig_View]  TAPBP [Vega]
ICGC DataPortalENSG00000231925
TCGA cBioPortalTAPBP
AceView (NCBI)TAPBP
Genatlas (Paris)TAPBP
WikiGenes6892
SOURCE (Princeton)TAPBP
Genetics Home Reference (NIH)TAPBP
Genomic and cartography
GoldenPath hg19 (UCSC)TAPBP  -     chr6:33267472-33282164 -  6p21.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TAPBP  -     6p21.32   [Description]    (hg38-Dec_2013)
EnsemblTAPBP - 6p21.32 [CytoView hg19]  TAPBP - 6p21.32 [CytoView hg38]
Mapping of homologs : NCBITAPBP [Mapview hg19]  TAPBP [Mapview hg38]
OMIM601962   604571   
Gene and transcription
Genbank (Entrez)AB010639 AF009510 AF029750 AF067286 AF314222
RefSeq transcript (Entrez)NM_003190 NM_172208 NM_172209
RefSeq genomic (Entrez)NC_000006 NC_018917 NG_009876 NT_007592 NT_113891 NT_167245 NT_167247 NT_167248 NW_004929326
Consensus coding sequences : CCDS (NCBI)TAPBP
Cluster EST : UnigeneHs.370937 [ NCBI ]
CGAP (NCI)Hs.370937
Alternative Splicing GalleryENSG00000231925
Gene ExpressionTAPBP [ NCBI-GEO ]   TAPBP [ EBI - ARRAY_EXPRESS ]   TAPBP [ SEEK ]   TAPBP [ MEM ]
Gene Expression Viewer (FireBrowse)TAPBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6892
GTEX Portal (Tissue expression)TAPBP
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15533   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15533  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15533
Splice isoforms : SwissVarO15533
PhosPhoSitePlusO15533
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_C1-set    Tapasin   
Domain families : Pfam (Sanger)C1-set (PF07654)   
Domain families : Pfam (NCBI)pfam07654   
Conserved Domain (NCBI)TAPBP
DMDM Disease mutations6892
Blocks (Seattle)TAPBP
PDB (SRS)3F8U   
PDB (PDBSum)3F8U   
PDB (IMB)3F8U   
PDB (RSDB)3F8U   
Structural Biology KnowledgeBase3F8U   
SCOP (Structural Classification of Proteins)3F8U   
CATH (Classification of proteins structures)3F8U   
SuperfamilyO15533
Human Protein AtlasENSG00000231925
Peptide AtlasO15533
HPRD09061
IPIIPI00007327   IPI00217384   IPI00645962   IPI01020770   IPI00922555   IPI01022425   IPI00439936   IPI00874287   IPI00746286   IPI00794567   IPI00942301   IPI00791568   IPI00792503   IPI01009657   IPI00944980   
Protein Interaction databases
DIP (DOE-UCLA)O15533
IntAct (EBI)O15533
FunCoupENSG00000231925
BioGRIDTAPBP
STRING (EMBL)TAPBP
ZODIACTAPBP
Ontologies - Pathways
QuickGOO15533
Ontology : AmiGOGolgi membrane  antigen processing and presentation of peptide antigen via MHC class I  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  protein complex assembly  retrograde vesicle-mediated transport, Golgi to ER  immune response  regulation of gene expression  peptide antigen-transporting ATPase activity  peptide transport  integral component of membrane  antigen processing and presentation of endogenous peptide antigen via MHC class I  MHC class I protein binding  peptide antigen binding  MHC class I peptide loading complex  TAP complex  amide transport  TAP1 binding  TAP1 binding  TAP2 binding  TAP2 binding  peptide antigen stabilization  unfolded protein binding  regulation of protein complex stability  integral component of lumenal side of endoplasmic reticulum membrane  
Ontology : EGO-EBIGolgi membrane  antigen processing and presentation of peptide antigen via MHC class I  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  protein complex assembly  retrograde vesicle-mediated transport, Golgi to ER  immune response  regulation of gene expression  peptide antigen-transporting ATPase activity  peptide transport  integral component of membrane  antigen processing and presentation of endogenous peptide antigen via MHC class I  MHC class I protein binding  peptide antigen binding  MHC class I peptide loading complex  TAP complex  amide transport  TAP1 binding  TAP1 binding  TAP2 binding  TAP2 binding  peptide antigen stabilization  unfolded protein binding  regulation of protein complex stability  integral component of lumenal side of endoplasmic reticulum membrane  
Pathways : KEGGAntigen processing and presentation   
NDEx NetworkTAPBP
Atlas of Cancer Signalling NetworkTAPBP
Wikipedia pathwaysTAPBP
Orthology - Evolution
OrthoDB6892
GeneTree (enSembl)ENSG00000231925
Phylogenetic Trees/Animal Genes : TreeFamTAPBP
HOVERGENO15533
HOGENOMO15533
Homologs : HomoloGeneTAPBP
Homology/Alignments : Family Browser (UCSC)TAPBP
Gene fusions - Rearrangements
Fusion : MitelmanTAPBP/DAXX [6p21.32/6p21.32]  
Fusion: TCGATAPBP 6p21.32 DAXX 6p21.32 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAPBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAPBP
dbVarTAPBP
ClinVarTAPBP
1000_GenomesTAPBP 
Exome Variant ServerTAPBP
ExAC (Exome Aggregation Consortium)TAPBP (select the gene name)
Genetic variants : HAPMAP6892
Genomic Variants (DGV)TAPBP [DGVbeta]
DECIPHER (Syndromes)6:33267472-33282164  ENSG00000231925
CONAN: Copy Number AnalysisTAPBP 
Mutations
ICGC Data PortalTAPBP 
TCGA Data PortalTAPBP 
Broad Tumor PortalTAPBP
OASIS PortalTAPBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAPBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAPBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch TAPBP
DgiDB (Drug Gene Interaction Database)TAPBP
DoCM (Curated mutations)TAPBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAPBP (select a term)
intoGenTAPBP
Cancer3DTAPBP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601962    604571   
Orphanet10349   
MedgenTAPBP
Genetic Testing Registry TAPBP
NextProtO15533 [Medical]
TSGene6892
GENETestsTAPBP
Huge Navigator TAPBP [HugePedia]
snp3D : Map Gene to Disease6892
BioCentury BCIQTAPBP
ClinGenTAPBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6892
Chemical/Pharm GKB GenePA36331
Clinical trialTAPBP
Miscellaneous
canSAR (ICR)TAPBP (select the gene name)
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAPBP
EVEXTAPBP
GoPubMedTAPBP
iHOPTAPBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:30:18 CET 2017

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