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TARBP2 (TAR (HIV-1) RNA binding protein 2)

Identity

Alias_namesTAR (HIV-1) RNA binding protein 2
Alias_symbol (synonym)Trbp
Other aliasLOQS
TRBP
TRBP1
TRBP2
HGNC (Hugo) TARBP2
LocusID (NCBI) 6895
Atlas_Id 45570
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 53894705 and ends at 53900215 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TARBP2   11569
Cards
Entrez_Gene (NCBI)TARBP2  6895  TAR (HIV-1) RNA binding protein 2
AliasesLOQS; TRBP; TRBP1; TRBP2
GeneCards (Weizmann)TARBP2
Ensembl hg19 (Hinxton)ENSG00000139546 [Gene_View]  chr12:53894705-53900215 [Contig_View]  TARBP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000139546 [Gene_View]  chr12:53894705-53900215 [Contig_View]  TARBP2 [Vega]
ICGC DataPortalENSG00000139546
TCGA cBioPortalTARBP2
AceView (NCBI)TARBP2
Genatlas (Paris)TARBP2
WikiGenes6895
SOURCE (Princeton)TARBP2
Genetics Home Reference (NIH)TARBP2
Genomic and cartography
GoldenPath hg19 (UCSC)TARBP2  -     chr12:53894705-53900215 +  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TARBP2  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblTARBP2 - 12q13.13 [CytoView hg19]  TARBP2 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBITARBP2 [Mapview hg19]  TARBP2 [Mapview hg38]
OMIM605053   
Gene and transcription
Genbank (Entrez)AK290737 AK293728 AK309569 BC002419 BC005860
RefSeq transcript (Entrez)NM_004178 NM_134323 NM_134324
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)TARBP2
Cluster EST : UnigeneHs.604255 [ NCBI ]
CGAP (NCI)Hs.604255
Alternative Splicing GalleryENSG00000139546
Gene ExpressionTARBP2 [ NCBI-GEO ]   TARBP2 [ EBI - ARRAY_EXPRESS ]   TARBP2 [ SEEK ]   TARBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)TARBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6895
GTEX Portal (Tissue expression)TARBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15633   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15633  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15633
Splice isoforms : SwissVarQ15633
PhosPhoSitePlusQ15633
Domaine pattern : Prosite (Expaxy)DS_RBD (PS50137)   
Domains : Interpro (EBI)dsRBD_dom    TRBP2   
Domain families : Pfam (Sanger)dsrm (PF00035)   
Domain families : Pfam (NCBI)pfam00035   
Domain families : Smart (EMBL)DSRM (SM00358)  
Conserved Domain (NCBI)TARBP2
DMDM Disease mutations6895
Blocks (Seattle)TARBP2
PDB (SRS)2CPN    3ADL    3LLH    4WYQ   
PDB (PDBSum)2CPN    3ADL    3LLH    4WYQ   
PDB (IMB)2CPN    3ADL    3LLH    4WYQ   
PDB (RSDB)2CPN    3ADL    3LLH    4WYQ   
Structural Biology KnowledgeBase2CPN    3ADL    3LLH    4WYQ   
SCOP (Structural Classification of Proteins)2CPN    3ADL    3LLH    4WYQ   
CATH (Classification of proteins structures)2CPN    3ADL    3LLH    4WYQ   
SuperfamilyQ15633
Human Protein AtlasENSG00000139546
Peptide AtlasQ15633
HPRD05446
IPIIPI00847568   IPI00472583   IPI01021911   IPI01022047   IPI01021810   IPI01020764   IPI01021485   IPI01021637   IPI01021232   IPI01022571   IPI01020890   
Protein Interaction databases
DIP (DOE-UCLA)Q15633
IntAct (EBI)Q15633
FunCoupENSG00000139546
BioGRIDTARBP2
STRING (EMBL)TARBP2
ZODIACTARBP2
Ontologies - Pathways
QuickGOQ15633
Ontology : AmiGOdouble-stranded RNA binding  protein binding  nucleus  cytoplasm  cytosol  negative regulation of protein kinase activity  spermatid development  single fertilization  RISC complex  enzyme binding  production of siRNA involved in RNA interference  targeting of mRNA for destruction involved in RNA interference  gene silencing by RNA  pre-miRNA processing  micro-ribonucleoprotein complex  siRNA loading onto RISC involved in RNA interference  production of miRNAs involved in gene silencing by miRNA  siRNA binding  miRNA binding  multicellular organism growth  miRNA loading onto RISC involved in gene silencing by miRNA  pre-mRNA binding  protein homodimerization activity  positive regulation of viral genome replication  positive regulation of translation  regulation of viral transcription  protein N-terminus binding  perinuclear region of cytoplasm  negative regulation of defense response to virus by host  RISC-loading complex  pre-miRNA binding  pre-miRNA binding  
Ontology : EGO-EBIdouble-stranded RNA binding  protein binding  nucleus  cytoplasm  cytosol  negative regulation of protein kinase activity  spermatid development  single fertilization  RISC complex  enzyme binding  production of siRNA involved in RNA interference  targeting of mRNA for destruction involved in RNA interference  gene silencing by RNA  pre-miRNA processing  micro-ribonucleoprotein complex  siRNA loading onto RISC involved in RNA interference  production of miRNAs involved in gene silencing by miRNA  siRNA binding  miRNA binding  multicellular organism growth  miRNA loading onto RISC involved in gene silencing by miRNA  pre-mRNA binding  protein homodimerization activity  positive regulation of viral genome replication  positive regulation of translation  regulation of viral transcription  protein N-terminus binding  perinuclear region of cytoplasm  negative regulation of defense response to virus by host  RISC-loading complex  pre-miRNA binding  pre-miRNA binding  
NDEx NetworkTARBP2
Atlas of Cancer Signalling NetworkTARBP2
Wikipedia pathwaysTARBP2
Orthology - Evolution
OrthoDB6895
GeneTree (enSembl)ENSG00000139546
Phylogenetic Trees/Animal Genes : TreeFamTARBP2
HOVERGENQ15633
HOGENOMQ15633
Homologs : HomoloGeneTARBP2
Homology/Alignments : Family Browser (UCSC)TARBP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTARBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TARBP2
dbVarTARBP2
ClinVarTARBP2
1000_GenomesTARBP2 
Exome Variant ServerTARBP2
ExAC (Exome Aggregation Consortium)TARBP2 (select the gene name)
Genetic variants : HAPMAP6895
Genomic Variants (DGV)TARBP2 [DGVbeta]
DECIPHER (Syndromes)12:53894705-53900215  ENSG00000139546
CONAN: Copy Number AnalysisTARBP2 
Mutations
ICGC Data PortalTARBP2 
TCGA Data PortalTARBP2 
Broad Tumor PortalTARBP2
OASIS PortalTARBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTARBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTARBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TARBP2
DgiDB (Drug Gene Interaction Database)TARBP2
DoCM (Curated mutations)TARBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TARBP2 (select a term)
intoGenTARBP2
Cancer3DTARBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605053   
Orphanet
MedgenTARBP2
Genetic Testing Registry TARBP2
NextProtQ15633 [Medical]
TSGene6895
GENETestsTARBP2
Huge Navigator TARBP2 [HugePedia]
snp3D : Map Gene to Disease6895
BioCentury BCIQTARBP2
ClinGenTARBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6895
Chemical/Pharm GKB GenePA36334
Clinical trialTARBP2
Miscellaneous
canSAR (ICR)TARBP2 (select the gene name)
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTARBP2
EVEXTARBP2
GoPubMedTARBP2
iHOPTARBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:30:19 CET 2017

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