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TARSL2 (threonyl-tRNA synthetase like 2)

Identity

Alias_symbol (synonym)FLJ25005
Other alias-
HGNC (Hugo) TARSL2
LocusID (NCBI) 123283
Atlas_Id 74483
Location 15q26.3  [Link to chromosome band 15q26]
Location_base_pair Starts at 101653752 and ends at 101724442 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
UCHL5 (1q31.2) / TARSL2 (15q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TARSL2   24728
Cards
Entrez_Gene (NCBI)TARSL2  123283  threonyl-tRNA synthetase like 2
Aliases
GeneCards (Weizmann)TARSL2
Ensembl hg19 (Hinxton)ENSG00000185418 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185418 [Gene_View]  chr15:101653752-101724442 [Contig_View]  TARSL2 [Vega]
ICGC DataPortalENSG00000185418
TCGA cBioPortalTARSL2
AceView (NCBI)TARSL2
Genatlas (Paris)TARSL2
WikiGenes123283
SOURCE (Princeton)TARSL2
Genetics Home Reference (NIH)TARSL2
Genomic and cartography
GoldenPath hg38 (UCSC)TARSL2  -     chr15:101653752-101724442 -  15q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TARSL2  -     15q26.3   [Description]    (hg19-Feb_2009)
EnsemblTARSL2 - 15q26.3 [CytoView hg19]  TARSL2 - 15q26.3 [CytoView hg38]
Mapping of homologs : NCBITARSL2 [Mapview hg19]  TARSL2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK056653 AK057734 AL833188 AW161214 BC035827
RefSeq transcript (Entrez)NM_152334
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TARSL2
Cluster EST : UnigeneHs.657163 [ NCBI ]
CGAP (NCI)Hs.657163
Alternative Splicing GalleryENSG00000185418
Gene ExpressionTARSL2 [ NCBI-GEO ]   TARSL2 [ EBI - ARRAY_EXPRESS ]   TARSL2 [ SEEK ]   TARSL2 [ MEM ]
Gene Expression Viewer (FireBrowse)TARSL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)123283
GTEX Portal (Tissue expression)TARSL2
Human Protein AtlasENSG00000185418-TARSL2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA2RTX5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA2RTX5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA2RTX5
Splice isoforms : SwissVarA2RTX5
Catalytic activity : Enzyme6.1.1.3 [ Enzyme-Expasy ]   6.1.1.36.1.1.3 [ IntEnz-EBI ]   6.1.1.3 [ BRENDA ]   6.1.1.3 [ KEGG ]   
PhosPhoSitePlusA2RTX5
Domaine pattern : Prosite (Expaxy)AA_TRNA_LIGASE_II (PS50862)   
Domains : Interpro (EBI)aa-tRNA-synt_IIb    aa-tRNA-synth_II    Anticodon-bd    Beta-grasp_dom    TGS    TGS-like    Thr-tRNA-ligase_IIa    Thr/Ala-tRNA-synth_IIc_edit    ThrRS_core    tRNA_SAD   
Domain families : Pfam (Sanger)HGTP_anticodon (PF03129)    TGS (PF02824)    tRNA-synt_2b (PF00587)    tRNA_SAD (PF07973)   
Domain families : Pfam (NCBI)pfam03129    pfam02824    pfam00587    pfam07973   
Domain families : Smart (EMBL)tRNA_SAD (SM00863)  
Conserved Domain (NCBI)TARSL2
DMDM Disease mutations123283
Blocks (Seattle)TARSL2
SuperfamilyA2RTX5
Human Protein Atlas [tissue]ENSG00000185418-TARSL2 [tissue]
Peptide AtlasA2RTX5
HPRD15469
IPIIPI00328082   IPI00892711   IPI01014077   
Protein Interaction databases
DIP (DOE-UCLA)A2RTX5
IntAct (EBI)A2RTX5
FunCoupENSG00000185418
BioGRIDTARSL2
STRING (EMBL)TARSL2
ZODIACTARSL2
Ontologies - Pathways
QuickGOA2RTX5
Ontology : AmiGOmolecular_function  threonine-tRNA ligase activity  protein binding  ATP binding  cellular_component  cytoplasm  threonyl-tRNA aminoacylation  biological_process  
Ontology : EGO-EBImolecular_function  threonine-tRNA ligase activity  protein binding  ATP binding  cellular_component  cytoplasm  threonyl-tRNA aminoacylation  biological_process  
Pathways : KEGGAminoacyl-tRNA biosynthesis   
NDEx NetworkTARSL2
Atlas of Cancer Signalling NetworkTARSL2
Wikipedia pathwaysTARSL2
Orthology - Evolution
OrthoDB123283
GeneTree (enSembl)ENSG00000185418
Phylogenetic Trees/Animal Genes : TreeFamTARSL2
HOVERGENA2RTX5
HOGENOMA2RTX5
Homologs : HomoloGeneTARSL2
Homology/Alignments : Family Browser (UCSC)TARSL2
Gene fusions - Rearrangements
Fusion: Tumor Portal TARSL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTARSL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TARSL2
dbVarTARSL2
ClinVarTARSL2
1000_GenomesTARSL2 
Exome Variant ServerTARSL2
ExAC (Exome Aggregation Consortium)ENSG00000185418
GNOMAD BrowserENSG00000185418
Genetic variants : HAPMAP123283
Genomic Variants (DGV)TARSL2 [DGVbeta]
DECIPHERTARSL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTARSL2 
Mutations
ICGC Data PortalTARSL2 
TCGA Data PortalTARSL2 
Broad Tumor PortalTARSL2
OASIS PortalTARSL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTARSL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTARSL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TARSL2
DgiDB (Drug Gene Interaction Database)TARSL2
DoCM (Curated mutations)TARSL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TARSL2 (select a term)
intoGenTARSL2
Cancer3DTARSL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTARSL2
Genetic Testing Registry TARSL2
NextProtA2RTX5 [Medical]
TSGene123283
GENETestsTARSL2
Target ValidationTARSL2
Huge Navigator TARSL2 [HugePedia]
snp3D : Map Gene to Disease123283
BioCentury BCIQTARSL2
ClinGenTARSL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD123283
Chemical/Pharm GKB GenePA128394753
Clinical trialTARSL2
Miscellaneous
canSAR (ICR)TARSL2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTARSL2
EVEXTARSL2
GoPubMedTARSL2
iHOPTARSL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:31:42 CET 2017

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