Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TAS1R1 (taste receptor, type 1, member 1)

Identity

Alias_namesGPR70
G protein-coupled receptor 70
taste receptor, type 1, member 1
Alias_symbol (synonym)T1R1
TR1
Other aliasGM148
HGNC (Hugo) TAS1R1
LocusID (NCBI) 80835
Atlas_Id 74484
Location 1p36.31  [Link to chromosome band 1p36]
Location_base_pair Starts at 6615338 and ends at 6639817 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ZBTB48 (1p36.31) / TAS1R1 (1p36.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAS1R1   14448
Cards
Entrez_Gene (NCBI)TAS1R1  80835  taste receptor, type 1, member 1
AliasesGM148; GPR70; T1R1; TR1
GeneCards (Weizmann)TAS1R1
Ensembl hg19 (Hinxton)ENSG00000173662 [Gene_View]  chr1:6615338-6639817 [Contig_View]  TAS1R1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000173662 [Gene_View]  chr1:6615338-6639817 [Contig_View]  TAS1R1 [Vega]
ICGC DataPortalENSG00000173662
TCGA cBioPortalTAS1R1
AceView (NCBI)TAS1R1
Genatlas (Paris)TAS1R1
WikiGenes80835
SOURCE (Princeton)TAS1R1
Genetics Home Reference (NIH)TAS1R1
Genomic and cartography
GoldenPath hg19 (UCSC)TAS1R1  -     chr1:6615338-6639817 +  1p36.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TAS1R1  -     1p36.31   [Description]    (hg38-Dec_2013)
EnsemblTAS1R1 - 1p36.31 [CytoView hg19]  TAS1R1 - 1p36.31 [CytoView hg38]
Mapping of homologs : NCBITAS1R1 [Mapview hg19]  TAS1R1 [Mapview hg38]
OMIM606225   
Gene and transcription
Genbank (Entrez)AF387617 AF387618 AF387619 AF387620 AI742401
RefSeq transcript (Entrez)NM_138697 NM_177539 NM_177540 NM_177541
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)TAS1R1
Cluster EST : UnigeneHs.124574 [ NCBI ]
CGAP (NCI)Hs.124574
Alternative Splicing GalleryENSG00000173662
Gene ExpressionTAS1R1 [ NCBI-GEO ]   TAS1R1 [ EBI - ARRAY_EXPRESS ]   TAS1R1 [ SEEK ]   TAS1R1 [ MEM ]
Gene Expression Viewer (FireBrowse)TAS1R1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80835
GTEX Portal (Tissue expression)TAS1R1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7RTX1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7RTX1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7RTX1
Splice isoforms : SwissVarQ7RTX1
PhosPhoSitePlusQ7RTX1
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F3_2 (PS00980)    G_PROTEIN_RECEP_F3_3 (PS00981)    G_PROTEIN_RECEP_F3_4 (PS50259)   
Domains : Interpro (EBI)ANF_lig-bd_rcpt    GPCR_3    GPCR_3_9-Cys_dom    GPCR_3_C    GPCR_3_CS    Peripla_BP_I   
Domain families : Pfam (Sanger)7tm_3 (PF00003)    ANF_receptor (PF01094)    NCD3G (PF07562)   
Domain families : Pfam (NCBI)pfam00003    pfam01094    pfam07562   
Conserved Domain (NCBI)TAS1R1
DMDM Disease mutations80835
Blocks (Seattle)TAS1R1
SuperfamilyQ7RTX1
Human Protein AtlasENSG00000173662
Peptide AtlasQ7RTX1
HPRD06939
IPIIPI00332575   IPI00291392   IPI00514989   IPI00220275   IPI01015772   IPI01014753   
Protein Interaction databases
DIP (DOE-UCLA)Q7RTX1
IntAct (EBI)Q7RTX1
FunCoupENSG00000173662
BioGRIDTAS1R1
STRING (EMBL)TAS1R1
ZODIACTAS1R1
Ontologies - Pathways
QuickGOQ7RTX1
Ontology : AmiGOplasma membrane  G-protein coupled receptor signaling pathway  taste receptor activity  integral component of membrane  protein heterodimerization activity  detection of chemical stimulus involved in sensory perception of taste  detection of chemical stimulus involved in sensory perception of taste  sensory perception of umami taste  
Ontology : EGO-EBIplasma membrane  G-protein coupled receptor signaling pathway  taste receptor activity  integral component of membrane  protein heterodimerization activity  detection of chemical stimulus involved in sensory perception of taste  detection of chemical stimulus involved in sensory perception of taste  sensory perception of umami taste  
Pathways : KEGGTaste transduction   
NDEx NetworkTAS1R1
Atlas of Cancer Signalling NetworkTAS1R1
Wikipedia pathwaysTAS1R1
Orthology - Evolution
OrthoDB80835
GeneTree (enSembl)ENSG00000173662
Phylogenetic Trees/Animal Genes : TreeFamTAS1R1
HOVERGENQ7RTX1
HOGENOMQ7RTX1
Homologs : HomoloGeneTAS1R1
Homology/Alignments : Family Browser (UCSC)TAS1R1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAS1R1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAS1R1
dbVarTAS1R1
ClinVarTAS1R1
1000_GenomesTAS1R1 
Exome Variant ServerTAS1R1
ExAC (Exome Aggregation Consortium)TAS1R1 (select the gene name)
Genetic variants : HAPMAP80835
Genomic Variants (DGV)TAS1R1 [DGVbeta]
DECIPHER (Syndromes)1:6615338-6639817  ENSG00000173662
CONAN: Copy Number AnalysisTAS1R1 
Mutations
ICGC Data PortalTAS1R1 
TCGA Data PortalTAS1R1 
Broad Tumor PortalTAS1R1
OASIS PortalTAS1R1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAS1R1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAS1R1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAS1R1
DgiDB (Drug Gene Interaction Database)TAS1R1
DoCM (Curated mutations)TAS1R1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAS1R1 (select a term)
intoGenTAS1R1
Cancer3DTAS1R1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606225   
Orphanet
MedgenTAS1R1
Genetic Testing Registry TAS1R1
NextProtQ7RTX1 [Medical]
TSGene80835
GENETestsTAS1R1
Huge Navigator TAS1R1 [HugePedia]
snp3D : Map Gene to Disease80835
BioCentury BCIQTAS1R1
ClinGenTAS1R1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80835
Chemical/Pharm GKB GenePA37882
Clinical trialTAS1R1
Miscellaneous
canSAR (ICR)TAS1R1 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAS1R1
EVEXTAS1R1
GoPubMedTAS1R1
iHOPTAS1R1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:47:24 CET 2017

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