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TAS1R2 (taste 1 receptor member 2)

Identity

Alias (NCBI)GPR71
T1R2
TR2
HGNC (Hugo) TAS1R2
HGNC Alias symbT1R2
TR2
HGNC Previous nameGPR71
HGNC Previous nameG protein-coupled receptor 71
 taste receptor, type 1, member 2
LocusID (NCBI) 80834
Atlas_Id 74485
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 18839599 and ends at 18860347 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAS1R2   14905
Cards
Entrez_Gene (NCBI)TAS1R2    taste 1 receptor member 2
AliasesGPR71; T1R2; TR2
GeneCards (Weizmann)TAS1R2
Ensembl hg19 (Hinxton)ENSG00000179002 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179002 [Gene_View]  ENSG00000179002 [Sequence]  chr1:18839599-18860347 [Contig_View]  TAS1R2 [Vega]
ICGC DataPortalENSG00000179002
TCGA cBioPortalTAS1R2
AceView (NCBI)TAS1R2
Genatlas (Paris)TAS1R2
SOURCE (Princeton)TAS1R2
Genetics Home Reference (NIH)TAS1R2
Genomic and cartography
GoldenPath hg38 (UCSC)TAS1R2  -     chr1:18839599-18860347 -  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAS1R2  -     1p36.13   [Description]    (hg19-Feb_2009)
GoldenPathTAS1R2 - 1p36.13 [CytoView hg19]  TAS1R2 - 1p36.13 [CytoView hg38]
ImmunoBaseENSG00000179002
Genome Data Viewer NCBITAS1R2 [Mapview hg19]  
OMIM606226   
Gene and transcription
Genbank (Entrez)BK000151
RefSeq transcript (Entrez)NM_152232
Consensus coding sequences : CCDS (NCBI)TAS1R2
Gene ExpressionTAS1R2 [ NCBI-GEO ]   TAS1R2 [ EBI - ARRAY_EXPRESS ]   TAS1R2 [ SEEK ]   TAS1R2 [ MEM ]
Gene Expression Viewer (FireBrowse)TAS1R2 [ Firebrowse - Broad ]
GenevisibleExpression of TAS1R2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80834
GTEX Portal (Tissue expression)TAS1R2
Human Protein AtlasENSG00000179002-TAS1R2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TE23   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TE23  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TE23
PhosPhoSitePlusQ8TE23
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F3_2 (PS00980)    G_PROTEIN_RECEP_F3_4 (PS50259)   
Domains : Interpro (EBI)ANF_lig-bd_rcpt    GPCR_3    GPCR_3_9-Cys_dom    GPCR_3_9-Cys_sf    GPCR_3_C    GPCR_3_Ca_sens_rcpt-rel    GPCR_3_CS    Peripla_BP_I   
Domain families : Pfam (Sanger)7tm_3 (PF00003)    ANF_receptor (PF01094)    NCD3G (PF07562)   
Domain families : Pfam (NCBI)pfam00003    pfam01094    pfam07562   
Conserved Domain (NCBI)TAS1R2
SuperfamilyQ8TE23
AlphaFold pdb e-kbQ8TE23   
Human Protein Atlas [tissue]ENSG00000179002-TAS1R2 [tissue]
HPRD06940
Protein Interaction databases
DIP (DOE-UCLA)Q8TE23
IntAct (EBI)Q8TE23
BioGRIDTAS1R2
STRING (EMBL)TAS1R2
ZODIACTAS1R2
Ontologies - Pathways
QuickGOQ8TE23
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of sweet taste  G protein-coupled receptor activity  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  taste receptor activity  taste receptor activity  integral component of membrane  positive regulation of cytokinesis  sweet taste receptor activity  sweet taste receptor activity  receptor complex  sensory perception of sweet taste  sensory perception of sweet taste  sweet taste receptor complex  sweet taste receptor complex  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of sweet taste  G protein-coupled receptor activity  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  taste receptor activity  taste receptor activity  integral component of membrane  positive regulation of cytokinesis  sweet taste receptor activity  sweet taste receptor activity  receptor complex  sensory perception of sweet taste  sensory perception of sweet taste  sweet taste receptor complex  sweet taste receptor complex  
Pathways : KEGGTaste transduction   
NDEx NetworkTAS1R2
Atlas of Cancer Signalling NetworkTAS1R2
Wikipedia pathwaysTAS1R2
Orthology - Evolution
OrthoDB80834
GeneTree (enSembl)ENSG00000179002
Phylogenetic Trees/Animal Genes : TreeFamTAS1R2
Homologs : HomoloGeneTAS1R2
Homology/Alignments : Family Browser (UCSC)TAS1R2
Gene fusions - Rearrangements
Fusion : QuiverTAS1R2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAS1R2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAS1R2
dbVarTAS1R2
ClinVarTAS1R2
MonarchTAS1R2
1000_GenomesTAS1R2 
Exome Variant ServerTAS1R2
GNOMAD BrowserENSG00000179002
Varsome BrowserTAS1R2
ACMGTAS1R2 variants
VarityQ8TE23
Genomic Variants (DGV)TAS1R2 [DGVbeta]
DECIPHERTAS1R2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAS1R2 
Mutations
ICGC Data PortalTAS1R2 
TCGA Data PortalTAS1R2 
Broad Tumor PortalTAS1R2
OASIS PortalTAS1R2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAS1R2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAS1R2
Mutations and Diseases : HGMDTAS1R2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAS1R2
DgiDB (Drug Gene Interaction Database)TAS1R2
DoCM (Curated mutations)TAS1R2
CIViC (Clinical Interpretations of Variants in Cancer)TAS1R2
Cancer3DTAS1R2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606226   
Orphanet
DisGeNETTAS1R2
MedgenTAS1R2
Genetic Testing Registry TAS1R2
NextProtQ8TE23 [Medical]
GENETestsTAS1R2
Target ValidationTAS1R2
Huge Navigator TAS1R2 [HugePedia]
ClinGenTAS1R2
Clinical trials, drugs, therapy
MyCancerGenomeTAS1R2
Protein Interactions : CTDTAS1R2
Pharm GKB GenePA37919
PharosQ8TE23
Clinical trialTAS1R2
Miscellaneous
canSAR (ICR)TAS1R2
HarmonizomeTAS1R2
DataMed IndexTAS1R2
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAS1R2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:24:51 CEST 2021

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