TAS2R3 (taste 2 receptor member 3)

2021-06-01  

Identity

HGNC
LOCATION
7q34
LOCUSID
ALIAS
T2R3

Other Information

Locus ID:

NCBI: 50831
MIM: 604868
HGNC: 14910
Ensembl: ENSG00000127362

Variants:

dbSNP: 50831
ClinVar: 50831
TCGA: ENSG00000127362
COSMIC: TAS2R3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127362ENST00000247879Q9NYW6

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
193723762009Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.299
267851642016Differential bitterness in capsaicin, piperine, and ethanol associates with polymorphisms in multiple bitter taste receptor genes.13
223972212012Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues.2
303019232018Genetic variations in TAS2R3 and TAS2R4 bitterness receptors modify papillary carcinoma risk and thyroid function in Korean females.2

Citation

Dessen P

TAS2R3 (taste 2 receptor member 3)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58284/tas2r3