TAS2R38 (taste 2 receptor member 38)

2003-02-01  

Identity

HGNC
LOCATION
7q34
LOCUSID
ALIAS
PTC,T2R38,T2R61,THIOT
FUSION GENES

Other Information

Locus ID:

NCBI: 5726
MIM: 607751
HGNC: 9584
Ensembl: ENSG00000257138

Variants:

dbSNP: 5726
ClinVar: 5726
TCGA: ENSG00000257138
COSMIC: TAS2R38

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000257138ENST00000547270P59533

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
125956902003Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide.218
230416242012T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection.162
156874292005Genetic and environmental determinants of bitter perception and sweet preferences.133
149974222004Natural selection and molecular evolution in PTC, a bitter-taste receptor gene.86
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
182090192008Supertasting and PROP bitterness depends on more than the TAS2R38 gene.84
182090192008Supertasting and PROP bitterness depends on more than the TAS2R38 gene.84
182090192008Supertasting and PROP bitterness depends on more than the TAS2R38 gene.84
206757122010The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.58
187196312008Variation in the bitter-taste receptor gene TAS2R38, and adiposity in a genetically isolated population in Southern Italy.48

Citation

Dessen P

TAS2R38 (taste 2 receptor member 38)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42471/tas2r38