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TAS2R40 (taste 2 receptor member 40)

Identity

Alias (NCBI)GPR60
T2R40
T2R58
HGNC (Hugo) TAS2R40
HGNC Previous nameGPR60
HGNC Previous nameG protein-coupled receptor 60
 taste receptor, type 2, member 40
LocusID (NCBI) 259286
Atlas_Id 74497
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 143222037 and ends at 143223079 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAS2R40   18885
Cards
Entrez_Gene (NCBI)TAS2R40    taste 2 receptor member 40
AliasesGPR60; T2R40; T2R58
GeneCards (Weizmann)TAS2R40
Ensembl hg19 (Hinxton)ENSG00000221937 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000221937 [Gene_View]  ENSG00000221937 [Sequence]  chr7:143222037-143223079 [Contig_View]  TAS2R40 [Vega]
ICGC DataPortalENSG00000221937
TCGA cBioPortalTAS2R40
AceView (NCBI)TAS2R40
Genatlas (Paris)TAS2R40
SOURCE (Princeton)TAS2R40
Genetics Home Reference (NIH)TAS2R40
Genomic and cartography
GoldenPath hg38 (UCSC)TAS2R40  -     chr7:143222037-143223079 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAS2R40  -     7q34   [Description]    (hg19-Feb_2009)
GoldenPathTAS2R40 - 7q34 [CytoView hg19]  TAS2R40 - 7q34 [CytoView hg38]
ImmunoBaseENSG00000221937
Genome Data Viewer NCBITAS2R40 [Mapview hg19]  
OMIM613964   
Gene and transcription
Genbank (Entrez)BC101795 BC101797
RefSeq transcript (Entrez)NM_176882
Consensus coding sequences : CCDS (NCBI)TAS2R40
Gene ExpressionTAS2R40 [ NCBI-GEO ]   TAS2R40 [ EBI - ARRAY_EXPRESS ]   TAS2R40 [ SEEK ]   TAS2R40 [ MEM ]
Gene Expression Viewer (FireBrowse)TAS2R40 [ Firebrowse - Broad ]
GenevisibleExpression of TAS2R40 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)259286
GTEX Portal (Tissue expression)TAS2R40
Human Protein AtlasENSG00000221937-TAS2R40 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP59535   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP59535  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP59535
PhosPhoSitePlusP59535
Domains : Interpro (EBI)TAS2R   
Domain families : Pfam (Sanger)TAS2R (PF05296)   
Domain families : Pfam (NCBI)pfam05296   
Conserved Domain (NCBI)TAS2R40
SuperfamilyP59535
AlphaFold pdb e-kbP59535   
Human Protein Atlas [tissue]ENSG00000221937-TAS2R40 [tissue]
HPRD18150
Protein Interaction databases
DIP (DOE-UCLA)P59535
IntAct (EBI)P59535
BioGRIDTAS2R40
STRING (EMBL)TAS2R40
ZODIACTAS2R40
Ontologies - Pathways
QuickGOP59535
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Pathways : KEGGTaste transduction   
NDEx NetworkTAS2R40
Atlas of Cancer Signalling NetworkTAS2R40
Wikipedia pathwaysTAS2R40
Orthology - Evolution
OrthoDB259286
GeneTree (enSembl)ENSG00000221937
Phylogenetic Trees/Animal Genes : TreeFamTAS2R40
Homologs : HomoloGeneTAS2R40
Homology/Alignments : Family Browser (UCSC)TAS2R40
Gene fusions - Rearrangements
Fusion : QuiverTAS2R40
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAS2R40 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAS2R40
dbVarTAS2R40
ClinVarTAS2R40
MonarchTAS2R40
1000_GenomesTAS2R40 
Exome Variant ServerTAS2R40
GNOMAD BrowserENSG00000221937
Varsome BrowserTAS2R40
ACMGTAS2R40 variants
VarityP59535
Genomic Variants (DGV)TAS2R40 [DGVbeta]
DECIPHERTAS2R40 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAS2R40 
Mutations
ICGC Data PortalTAS2R40 
TCGA Data PortalTAS2R40 
Broad Tumor PortalTAS2R40
OASIS PortalTAS2R40 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAS2R40  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAS2R40
Mutations and Diseases : HGMDTAS2R40
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAS2R40
DgiDB (Drug Gene Interaction Database)TAS2R40
DoCM (Curated mutations)TAS2R40
CIViC (Clinical Interpretations of Variants in Cancer)TAS2R40
Cancer3DTAS2R40
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613964   
Orphanet
DisGeNETTAS2R40
MedgenTAS2R40
Genetic Testing Registry TAS2R40
NextProtP59535 [Medical]
GENETestsTAS2R40
Target ValidationTAS2R40
Huge Navigator TAS2R40 [HugePedia]
ClinGenTAS2R40
Clinical trials, drugs, therapy
MyCancerGenomeTAS2R40
Protein Interactions : CTDTAS2R40
Pharm GKB GenePA38738
PharosP59535
Clinical trialTAS2R40
Miscellaneous
canSAR (ICR)TAS2R40
HarmonizomeTAS2R40
DataMed IndexTAS2R40
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAS2R40
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:24:52 CEST 2021

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