TAS2R43 (taste 2 receptor member 43)

2014-11-01 Affiliation

Identity

HGNC

TAS2R43

LOCATION

12p13.2

LOCUSID

259289

ALIAS

T2R43,T2R52

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 259289
MIM: 612668
HGNC: 18875
Ensembl: ENSG00000255374

Variants:

dbSNP: 259289
ClinVar: 259289
TCGA: ENSG00000255374
COSMIC: TAS2R43

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000255374	ENST00000531678	P59537

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Taste transduction	KEGG	ko04742
Taste transduction	KEGG	hsa04742
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR ligand binding	REACTOME	R-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)	REACTOME	R-HSA-420499
GPCR downstream signaling	REACTOME	R-HSA-388396
G alpha (i) signalling events	REACTOME	R-HSA-418594

References

Pubmed ID	Year	Title	Citations
26037485	2015	A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs.	10
22397221	2012	Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues.	2
15537898	2004	Bitter taste receptors for saccharin and acesulfame K.	0
17702579	2007	Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.	0
22964302	2012	Extraoral bitter taste receptors as mediators of off-target drug effects.	0
23050764	2012	Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN).	0
24647340	2014	Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking.	0
26391354	2015	Children's perceptions about medicines: individual differences and taste.	0

Citation

Dessen P

TAS2R43 (taste 2 receptor member 43)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74500/tas2r43