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TAS2R8 (taste 2 receptor member 8)

Identity

Alias (NCBI)T2R8
TRB5
HGNC (Hugo) TAS2R8
HGNC Alias symbT2R8
TRB5
HGNC Previous nametaste receptor, type 2, member 8
LocusID (NCBI) 50836
Atlas_Id 57103
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10806051 and ends at 10807302 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAS2R8   14915
Cards
Entrez_Gene (NCBI)TAS2R8    taste 2 receptor member 8
AliasesT2R8; TRB5
GeneCards (Weizmann)TAS2R8
Ensembl hg19 (Hinxton)ENSG00000121314 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121314 [Gene_View]  ENSG00000121314 [Sequence]  chr12:10806051-10807302 [Contig_View]  TAS2R8 [Vega]
ICGC DataPortalENSG00000121314
TCGA cBioPortalTAS2R8
AceView (NCBI)TAS2R8
Genatlas (Paris)TAS2R8
SOURCE (Princeton)TAS2R8
Genetics Home Reference (NIH)TAS2R8
Genomic and cartography
GoldenPath hg38 (UCSC)TAS2R8  -     chr12:10806051-10807302 -  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAS2R8  -     12p13.2   [Description]    (hg19-Feb_2009)
GoldenPathTAS2R8 - 12p13.2 [CytoView hg19]  TAS2R8 - 12p13.2 [CytoView hg38]
ImmunoBaseENSG00000121314
Genome Data Viewer NCBITAS2R8 [Mapview hg19]  
OMIM604794   
Gene and transcription
Genbank (Entrez)BC069084 BC069551 BC096701 BC096735 BC098167
RefSeq transcript (Entrez)NM_023918
Consensus coding sequences : CCDS (NCBI)TAS2R8
Gene ExpressionTAS2R8 [ NCBI-GEO ]   TAS2R8 [ EBI - ARRAY_EXPRESS ]   TAS2R8 [ SEEK ]   TAS2R8 [ MEM ]
Gene Expression Viewer (FireBrowse)TAS2R8 [ Firebrowse - Broad ]
GenevisibleExpression of TAS2R8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50836
GTEX Portal (Tissue expression)TAS2R8
Human Protein AtlasENSG00000121314-TAS2R8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYW2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYW2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYW2
PhosPhoSitePlusQ9NYW2
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn_7TM    TAS2R   
Domain families : Pfam (Sanger)TAS2R (PF05296)   
Domain families : Pfam (NCBI)pfam05296   
Conserved Domain (NCBI)TAS2R8
SuperfamilyQ9NYW2
AlphaFold pdb e-kbQ9NYW2   
Human Protein Atlas [tissue]ENSG00000121314-TAS2R8 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9NYW2
IntAct (EBI)Q9NYW2
BioGRIDTAS2R8
STRING (EMBL)TAS2R8
ZODIACTAS2R8
Ontologies - Pathways
QuickGOQ9NYW2
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  protein binding  plasma membrane  G protein-coupled receptor signaling pathway  taste receptor activity  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  protein binding  plasma membrane  G protein-coupled receptor signaling pathway  taste receptor activity  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Pathways : KEGGTaste transduction   
NDEx NetworkTAS2R8
Atlas of Cancer Signalling NetworkTAS2R8
Wikipedia pathwaysTAS2R8
Orthology - Evolution
OrthoDB50836
GeneTree (enSembl)ENSG00000121314
Phylogenetic Trees/Animal Genes : TreeFamTAS2R8
Homologs : HomoloGeneTAS2R8
Homology/Alignments : Family Browser (UCSC)TAS2R8
Gene fusions - Rearrangements
Fusion : QuiverTAS2R8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAS2R8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAS2R8
dbVarTAS2R8
ClinVarTAS2R8
MonarchTAS2R8
1000_GenomesTAS2R8 
Exome Variant ServerTAS2R8
GNOMAD BrowserENSG00000121314
Varsome BrowserTAS2R8
ACMGTAS2R8 variants
VarityQ9NYW2
Genomic Variants (DGV)TAS2R8 [DGVbeta]
DECIPHERTAS2R8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAS2R8 
Mutations
ICGC Data PortalTAS2R8 
TCGA Data PortalTAS2R8 
Broad Tumor PortalTAS2R8
OASIS PortalTAS2R8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAS2R8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAS2R8
Mutations and Diseases : HGMDTAS2R8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAS2R8
DgiDB (Drug Gene Interaction Database)TAS2R8
DoCM (Curated mutations)TAS2R8
CIViC (Clinical Interpretations of Variants in Cancer)TAS2R8
Cancer3DTAS2R8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604794   
Orphanet
DisGeNETTAS2R8
MedgenTAS2R8
Genetic Testing Registry TAS2R8
NextProtQ9NYW2 [Medical]
GENETestsTAS2R8
Target ValidationTAS2R8
Huge Navigator TAS2R8 [HugePedia]
ClinGenTAS2R8
Clinical trials, drugs, therapy
MyCancerGenomeTAS2R8
Protein Interactions : CTDTAS2R8
Pharm GKB GenePA37926
PharosQ9NYW2
Clinical trialTAS2R8
Miscellaneous
canSAR (ICR)TAS2R8
HarmonizomeTAS2R8
DataMed IndexTAS2R8
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAS2R8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:18 CEST 2021

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