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TAS2R8 (taste 2 receptor member 8)

Identity

Alias_namestaste receptor, type 2, member 8
Alias_symbol (synonym)T2R8
TRB5
Other alias
HGNC (Hugo) TAS2R8
LocusID (NCBI) 50836
Atlas_Id 74506
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10806051 and ends at 10806980 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAS2R8   14915
Cards
Entrez_Gene (NCBI)TAS2R8  50836  taste 2 receptor member 8
AliasesT2R8; TRB5
GeneCards (Weizmann)TAS2R8
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr12:10806051-10806980 [Contig_View]  TAS2R8 [Vega]
TCGA cBioPortalTAS2R8
AceView (NCBI)TAS2R8
Genatlas (Paris)TAS2R8
WikiGenes50836
SOURCE (Princeton)TAS2R8
Genetics Home Reference (NIH)TAS2R8
Genomic and cartography
GoldenPath hg38 (UCSC)TAS2R8  -     chr12:10806051-10806980 -  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAS2R8  -     12p13.2   [Description]    (hg19-Feb_2009)
EnsemblTAS2R8 - 12p13.2 [CytoView hg19]  TAS2R8 - 12p13.2 [CytoView hg38]
Mapping of homologs : NCBITAS2R8 [Mapview hg19]  TAS2R8 [Mapview hg38]
OMIM604794   
Gene and transcription
Genbank (Entrez)BC069084 BC069551 BC096701 BC096735 BC098167
RefSeq transcript (Entrez)NM_023918
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_187658 NW_003571050
Consensus coding sequences : CCDS (NCBI)TAS2R8
Cluster EST : UnigeneHs.533755 [ NCBI ]
CGAP (NCI)Hs.533755
Gene ExpressionTAS2R8 [ NCBI-GEO ]   TAS2R8 [ EBI - ARRAY_EXPRESS ]   TAS2R8 [ SEEK ]   TAS2R8 [ MEM ]
Gene Expression Viewer (FireBrowse)TAS2R8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50836
GTEX Portal (Tissue expression)TAS2R8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYW2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYW2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYW2
Splice isoforms : SwissVarQ9NYW2
PhosPhoSitePlusQ9NYW2
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn_7TM    T2R   
Domain families : Pfam (Sanger)TAS2R (PF05296)   
Domain families : Pfam (NCBI)pfam05296   
Conserved Domain (NCBI)TAS2R8
DMDM Disease mutations50836
Blocks (Seattle)TAS2R8
SuperfamilyQ9NYW2
Peptide AtlasQ9NYW2
HPRD16072
IPIIPI00028325   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYW2
IntAct (EBI)Q9NYW2
BioGRIDTAS2R8
STRING (EMBL)TAS2R8
ZODIACTAS2R8
Ontologies - Pathways
QuickGOQ9NYW2
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor activity  plasma membrane  G-protein coupled receptor signaling pathway  taste receptor activity  integral component of membrane  bitter taste receptor activity  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor activity  plasma membrane  G-protein coupled receptor signaling pathway  taste receptor activity  integral component of membrane  bitter taste receptor activity  
Pathways : KEGGTaste transduction   
NDEx NetworkTAS2R8
Atlas of Cancer Signalling NetworkTAS2R8
Wikipedia pathwaysTAS2R8
Orthology - Evolution
OrthoDB50836
Phylogenetic Trees/Animal Genes : TreeFamTAS2R8
HOVERGENQ9NYW2
HOGENOMQ9NYW2
Homologs : HomoloGeneTAS2R8
Homology/Alignments : Family Browser (UCSC)TAS2R8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAS2R8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAS2R8
dbVarTAS2R8
ClinVarTAS2R8
1000_GenomesTAS2R8 
Exome Variant ServerTAS2R8
ExAC (Exome Aggregation Consortium)TAS2R8 (select the gene name)
Genetic variants : HAPMAP50836
Genomic Variants (DGV)TAS2R8 [DGVbeta]
DECIPHERTAS2R8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAS2R8 
Mutations
ICGC Data PortalTAS2R8 
TCGA Data PortalTAS2R8 
Broad Tumor PortalTAS2R8
OASIS PortalTAS2R8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAS2R8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAS2R8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAS2R8
DgiDB (Drug Gene Interaction Database)TAS2R8
DoCM (Curated mutations)TAS2R8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAS2R8 (select a term)
intoGenTAS2R8
Cancer3DTAS2R8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604794   
Orphanet
MedgenTAS2R8
Genetic Testing Registry TAS2R8
NextProtQ9NYW2 [Medical]
TSGene50836
GENETestsTAS2R8
Target ValidationTAS2R8
Huge Navigator TAS2R8 [HugePedia]
snp3D : Map Gene to Disease50836
BioCentury BCIQTAS2R8
ClinGenTAS2R8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD50836
Chemical/Pharm GKB GenePA37926
Clinical trialTAS2R8
Miscellaneous
canSAR (ICR)TAS2R8 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAS2R8
EVEXTAS2R8
GoPubMedTAS2R8
iHOPTAS2R8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:41:01 CEST 2017

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