Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TAT (tyrosine aminotransferase)

Identity

Other names-
HGNC (Hugo) TAT
LocusID (NCBI) 6898
Atlas_Id 42472
Location 16q22.2  [Link to chromosome band 16q22]
Location_base_pair Starts at 71600754 and ends at 71610998 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MAP9 (4q32.1) / TAT (16q22.2)PLCG1 (20q12) / TAT (16q22.2)TAT (16q22.2) / FOXO3 (6q21)
TAT (16q22.2) / PPP2R1B (11q23.1)MAP9 4q32.1 / TAT 16q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAT   11573
Cards
Entrez_Gene (NCBI)TAT  6898  tyrosine aminotransferase
Aliases
GeneCards (Weizmann)TAT
Ensembl hg19 (Hinxton)ENSG00000198650 [Gene_View]  chr16:71600754-71610998 [Contig_View]  TAT [Vega]
Ensembl hg38 (Hinxton)ENSG00000198650 [Gene_View]  chr16:71600754-71610998 [Contig_View]  TAT [Vega]
ICGC DataPortalENSG00000198650
TCGA cBioPortalTAT
AceView (NCBI)TAT
Genatlas (Paris)TAT
WikiGenes6898
SOURCE (Princeton)TAT
Genomic and cartography
GoldenPath hg19 (UCSC)TAT  -     chr16:71600754-71610998 -  16q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TAT  -     16q22.2   [Description]    (hg38-Dec_2013)
EnsemblTAT - 16q22.2 [CytoView hg19]  TAT - 16q22.2 [CytoView hg38]
Mapping of homologs : NCBITAT [Mapview hg19]  TAT [Mapview hg38]
OMIM276600   613018   
Gene and transcription
Genbank (Entrez)AK313380 BC020707 BC022292 BC130534 HM005657
RefSeq transcript (Entrez)NM_000353
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_008235 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)TAT
Cluster EST : UnigeneHs.161640 [ NCBI ]
CGAP (NCI)Hs.161640
Alternative Splicing GalleryENSG00000198650
Gene ExpressionTAT [ NCBI-GEO ]   TAT [ EBI - ARRAY_EXPRESS ]   TAT [ SEEK ]   TAT [ MEM ]
Gene Expression Viewer (FireBrowse)TAT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6898
GTEX Portal (Tissue expression)TAT
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17735 (Uniprot)
NextProtP17735  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17735
Splice isoforms : SwissVarP17735 (Swissvar)
Catalytic activity : Enzyme2.6.1.5 [ Enzyme-Expasy ]   2.6.1.52.6.1.5 [ IntEnz-EBI ]   2.6.1.5 [ BRENDA ]   2.6.1.5 [ KEGG ]   
PhosPhoSitePlusP17735
Domaine pattern : Prosite (Expaxy)AA_TRANSFER_CLASS_1 (PS00105)   
Domains : Interpro (EBI)Aminotransferase_I/II    NHTrfase_class1_PyrdxlP-BS    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2    Tyr_aminoTrfase_ubiquitination    TyrNic_aminoTrfase    Tyrosine_aminoTrfase   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)    TAT_ubiq (PF07706)   
Domain families : Pfam (NCBI)pfam00155    pfam07706   
DMDM Disease mutations6898
Blocks (Seattle)TAT
PDB (SRS)3DYD   
PDB (PDBSum)3DYD   
PDB (IMB)3DYD   
PDB (RSDB)3DYD   
Structural Biology KnowledgeBase3DYD   
SCOP (Structural Classification of Proteins)3DYD   
CATH (Classification of proteins structures)3DYD   
SuperfamilyP17735
Human Protein AtlasENSG00000198650
Peptide AtlasP17735
HPRD11776
IPIIPI00016764   IPI00383039   
Protein Interaction databases
DIP (DOE-UCLA)P17735
IntAct (EBI)P17735
FunCoupENSG00000198650
BioGRIDTAT
STRING (EMBL)TAT
ZODIACTAT
Ontologies - Pathways
QuickGOP17735
Ontology : AmiGOL-tyrosine:2-oxoglutarate aminotransferase activity  L-tyrosine:2-oxoglutarate aminotransferase activity  L-tyrosine:2-oxoglutarate aminotransferase activity  cellular_component  mitochondrion  cytosol  2-oxoglutarate metabolic process  glutamate metabolic process  L-phenylalanine catabolic process  L-phenylalanine catabolic process  tyrosine catabolic process  response to oxidative stress  biosynthetic process  amino acid binding  pyridoxal phosphate binding  response to mercury ion  response to glucocorticoid  L-phenylalanine:2-oxoglutarate aminotransferase activity  
Ontology : EGO-EBIL-tyrosine:2-oxoglutarate aminotransferase activity  L-tyrosine:2-oxoglutarate aminotransferase activity  L-tyrosine:2-oxoglutarate aminotransferase activity  cellular_component  mitochondrion  cytosol  2-oxoglutarate metabolic process  glutamate metabolic process  L-phenylalanine catabolic process  L-phenylalanine catabolic process  tyrosine catabolic process  response to oxidative stress  biosynthetic process  amino acid binding  pyridoxal phosphate binding  response to mercury ion  response to glucocorticoid  L-phenylalanine:2-oxoglutarate aminotransferase activity  
Pathways : KEGGUbiquinone and other terpenoid-quinone biosynthesis    Cysteine and methionine metabolism    Tyrosine metabolism    Phenylalanine metabolism    Phenylalanine, tyrosine and tryptophan biosynthesis   
NDEx Network
Atlas of Cancer Signalling NetworkTAT
Wikipedia pathwaysTAT
Orthology - Evolution
OrthoDB6898
GeneTree (enSembl)ENSG00000198650
Phylogenetic Trees/Animal Genes : TreeFamTAT
Homologs : HomoloGeneTAT
Homology/Alignments : Family Browser (UCSC)TAT
Gene fusions - Rearrangements
Fusion: TCGAMAP9 4q32.1 TAT 16q22.2 LGG
Polymorphisms : SNP, variants
NCBI Variation ViewerTAT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAT
dbVarTAT
ClinVarTAT
1000_GenomesTAT 
Exome Variant ServerTAT
ExAC (Exome Aggregation Consortium)TAT (select the gene name)
Genetic variants : HAPMAP6898
Genomic Variants (DGV)TAT [DGVbeta]
Mutations
ICGC Data PortalTAT 
TCGA Data PortalTAT 
Broad Tumor PortalTAT
OASIS PortalTAT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAT 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TAT
DgiDB (Drug Gene Interaction Database)TAT
DoCM (Curated mutations)TAT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAT (select a term)
intoGenTAT
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:71600754-71610998  ENSG00000198650
CONAN: Copy Number AnalysisTAT 
Mutations and Diseases : HGMDTAT
OMIM276600    613018   
MedgenTAT
Genetic Testing Registry TAT
NextProtP17735 [Medical]
TSGene6898
GENETestsTAT
Huge Navigator TAT [HugePedia]
snp3D : Map Gene to Disease6898
BioCentury BCIQTAT
ClinGenTAT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6898
Chemical/Pharm GKB GenePA36338
Clinical trialTAT
Miscellaneous
canSAR (ICR)TAT (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAT
EVEXTAT
GoPubMedTAT
iHOPTAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:10:04 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.