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TAT (tyrosine aminotransferase)

Identity

Alias (NCBI)-
HGNC (Hugo) TAT
LocusID (NCBI) 6898
Atlas_Id 42472
Location 16q22.2  [Link to chromosome band 16q22]
Location_base_pair Starts at 71565660 and ends at 71577092 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAP9 (4q32.1) / TAT (16q22.2)PLCG1 (20q12) / TAT (16q22.2)TAT (16q22.2) / FOXO3 (6q21)
TAT (16q22.2) / PPP2R1B (11q23.1)MAP9 4q32.1 / TAT 16q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAT   11573
Cards
Entrez_Gene (NCBI)TAT    tyrosine aminotransferase
Aliases
GeneCards (Weizmann)TAT
Ensembl hg19 (Hinxton)ENSG00000198650 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198650 [Gene_View]  ENSG00000198650 [Sequence]  chr16:71565660-71577092 [Contig_View]  TAT [Vega]
ICGC DataPortalENSG00000198650
TCGA cBioPortalTAT
AceView (NCBI)TAT
Genatlas (Paris)TAT
SOURCE (Princeton)TAT
Genetics Home Reference (NIH)TAT
Genomic and cartography
GoldenPath hg38 (UCSC)TAT  -     chr16:71565660-71577092 -  16q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAT  -     16q22.2   [Description]    (hg19-Feb_2009)
GoldenPathTAT - 16q22.2 [CytoView hg19]  TAT - 16q22.2 [CytoView hg38]
ImmunoBaseENSG00000198650
Genome Data Viewer NCBITAT [Mapview hg19]  
OMIM276600   613018   
Gene and transcription
Genbank (Entrez)AK313380 BC020707 BC022292 BC130534 HM005657
RefSeq transcript (Entrez)NM_000353
Consensus coding sequences : CCDS (NCBI)TAT
Gene ExpressionTAT [ NCBI-GEO ]   TAT [ EBI - ARRAY_EXPRESS ]   TAT [ SEEK ]   TAT [ MEM ]
Gene Expression Viewer (FireBrowse)TAT [ Firebrowse - Broad ]
GenevisibleExpression of TAT in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6898
GTEX Portal (Tissue expression)TAT
Human Protein AtlasENSG00000198650-TAT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17735   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17735  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17735
Catalytic activity : Enzyme2.6.1.5 [ Enzyme-Expasy ]   2.6.1.52.6.1.5 [ IntEnz-EBI ]   2.6.1.5 [ BRENDA ]   2.6.1.5 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP17735
Domaine pattern : Prosite (Expaxy)AA_TRANSFER_CLASS_1 (PS00105)   
Domains : Interpro (EBI)Aminotransferase_I/II    NHTrfase_class1_PyrdxlP-BS    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_dom1    PyrdxlP-dep_Trfase_major    Tyr_aminoTrfase_ubiquitination    TyrNic_aminoTrfase    Tyrosine_aminoTrfase   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)    TAT_ubiq (PF07706)   
Domain families : Pfam (NCBI)pfam00155    pfam07706   
Conserved Domain (NCBI)TAT
PDB (RSDB)3DYD   
PDB Europe3DYD   
PDB (PDBSum)3DYD   
PDB (IMB)3DYD   
Structural Biology KnowledgeBase3DYD   
SCOP (Structural Classification of Proteins)3DYD   
CATH (Classification of proteins structures)3DYD   
SuperfamilyP17735
AlphaFold pdb e-kbP17735   
Human Protein Atlas [tissue]ENSG00000198650-TAT [tissue]
HPRD11776
Protein Interaction databases
DIP (DOE-UCLA)P17735
IntAct (EBI)P17735
BioGRIDTAT
STRING (EMBL)TAT
ZODIACTAT
Ontologies - Pathways
QuickGOP17735
Ontology : AmiGOL-tyrosine:2-oxoglutarate aminotransferase activity  L-tyrosine:2-oxoglutarate aminotransferase activity  protein binding  cellular_component  mitochondrion  cytosol  2-oxoglutarate metabolic process  glutamate metabolic process  L-phenylalanine catabolic process  tyrosine catabolic process  tyrosine catabolic process  response to oxidative stress  biosynthetic process  amino acid binding  pyridoxal phosphate binding  identical protein binding  response to mercury ion  response to glucocorticoid  
Ontology : EGO-EBIL-tyrosine:2-oxoglutarate aminotransferase activity  L-tyrosine:2-oxoglutarate aminotransferase activity  protein binding  cellular_component  mitochondrion  cytosol  2-oxoglutarate metabolic process  glutamate metabolic process  L-phenylalanine catabolic process  tyrosine catabolic process  tyrosine catabolic process  response to oxidative stress  biosynthetic process  amino acid binding  pyridoxal phosphate binding  identical protein binding  response to mercury ion  response to glucocorticoid  
Pathways : KEGGUbiquinone and other terpenoid-quinone biosynthesis    Cysteine and methionine metabolism    Tyrosine metabolism    Phenylalanine metabolism    Phenylalanine, tyrosine and tryptophan biosynthesis   
NDEx NetworkTAT
Atlas of Cancer Signalling NetworkTAT
Wikipedia pathwaysTAT
Orthology - Evolution
OrthoDB6898
GeneTree (enSembl)ENSG00000198650
Phylogenetic Trees/Animal Genes : TreeFamTAT
Homologs : HomoloGeneTAT
Homology/Alignments : Family Browser (UCSC)TAT
Gene fusions - Rearrangements
Fusion : MitelmanMAP9/TAT [4q32.1/16q22.2]  
Fusion : QuiverTAT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAT
dbVarTAT
ClinVarTAT
MonarchTAT
1000_GenomesTAT 
Exome Variant ServerTAT
GNOMAD BrowserENSG00000198650
Varsome BrowserTAT
ACMGTAT variants
VarityP17735
Genomic Variants (DGV)TAT [DGVbeta]
DECIPHERTAT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAT 
Mutations
ICGC Data PortalTAT 
TCGA Data PortalTAT 
Broad Tumor PortalTAT
OASIS PortalTAT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAT  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAT
Mutations and Diseases : HGMDTAT
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAT
DgiDB (Drug Gene Interaction Database)TAT
DoCM (Curated mutations)TAT
CIViC (Clinical Interpretations of Variants in Cancer)TAT
Cancer3DTAT
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM276600    613018   
Orphanet8772   
DisGeNETTAT
MedgenTAT
Genetic Testing Registry TAT
NextProtP17735 [Medical]
GENETestsTAT
Target ValidationTAT
Huge Navigator TAT [HugePedia]
ClinGenTAT
Clinical trials, drugs, therapy
MyCancerGenomeTAT
Protein Interactions : CTDTAT
Pharm GKB GenePA36338
PharosP17735
Clinical trialTAT
Miscellaneous
canSAR (ICR)TAT
HarmonizomeTAT
DataMed IndexTAT
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:18 CEST 2021

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