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TATDN1 (TatD DNase domain containing 1)

Identity

Alias_symbol (synonym)CDA11
Other alias
HGNC (Hugo) TATDN1
LocusID (NCBI) 83940
Atlas_Id 54687
Location 8q24.13  [Link to chromosome band 8q24]
Location_base_pair Starts at 125500735 and ends at 125551329 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TATDN1 (8q24.13) / DEPTOR (8q24.12)TATDN1 (8q24.13) / GSDMB (17q12)TATDN1 (8q24.13) / MTSS1 (8q24.13)
TATDN1 (8q24.13) / OC90 (8q24.22)TATDN1 8q24.13 / OC90 8q24.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TATDN1   24220
Cards
Entrez_Gene (NCBI)TATDN1  83940  TatD DNase domain containing 1
AliasesCDA11
GeneCards (Weizmann)TATDN1
Ensembl hg19 (Hinxton)ENSG00000147687 [Gene_View]  chr8:125500735-125551329 [Contig_View]  TATDN1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000147687 [Gene_View]  chr8:125500735-125551329 [Contig_View]  TATDN1 [Vega]
ICGC DataPortalENSG00000147687
TCGA cBioPortalTATDN1
AceView (NCBI)TATDN1
Genatlas (Paris)TATDN1
WikiGenes83940
SOURCE (Princeton)TATDN1
Genetics Home Reference (NIH)TATDN1
Genomic and cartography
GoldenPath hg19 (UCSC)TATDN1  -     chr8:125500735-125551329 -  8q24.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TATDN1  -     8q24.13   [Description]    (hg38-Dec_2013)
EnsemblTATDN1 - 8q24.13 [CytoView hg19]  TATDN1 - 8q24.13 [CytoView hg38]
Mapping of homologs : NCBITATDN1 [Mapview hg19]  TATDN1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF212250 AK094861 AK125270 AK312204 AV729364
RefSeq transcript (Entrez)NM_001146160 NM_001317889 NM_001317890 NM_001317891 NM_032026
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)TATDN1
Cluster EST : UnigeneHs.170568 [ NCBI ]
CGAP (NCI)Hs.170568
Alternative Splicing GalleryENSG00000147687
Gene ExpressionTATDN1 [ NCBI-GEO ]   TATDN1 [ EBI - ARRAY_EXPRESS ]   TATDN1 [ SEEK ]   TATDN1 [ MEM ]
Gene Expression Viewer (FireBrowse)TATDN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83940
GTEX Portal (Tissue expression)TATDN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P1N9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P1N9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P1N9
Splice isoforms : SwissVarQ6P1N9
Catalytic activity : Enzyme3.1.21.- [ Enzyme-Expasy ]   3.1.21.-3.1.21.- [ IntEnz-EBI ]   3.1.21.- [ BRENDA ]   3.1.21.- [ KEGG ]   
PhosPhoSitePlusQ6P1N9
Domaine pattern : Prosite (Expaxy)TATD_3 (PS01091)   
Domains : Interpro (EBI)DNase_TatD-rel_CS    Metal_Hydrolase    TatD_family   
Domain families : Pfam (Sanger)TatD_DNase (PF01026)   
Domain families : Pfam (NCBI)pfam01026   
Conserved Domain (NCBI)TATDN1
DMDM Disease mutations83940
Blocks (Seattle)TATDN1
PDB (SRS)2XIO   
PDB (PDBSum)2XIO   
PDB (IMB)2XIO   
PDB (RSDB)2XIO   
Structural Biology KnowledgeBase2XIO   
SCOP (Structural Classification of Proteins)2XIO   
CATH (Classification of proteins structures)2XIO   
SuperfamilyQ6P1N9
Human Protein AtlasENSG00000147687
Peptide AtlasQ6P1N9
HPRD11621
IPIIPI00012463   IPI00792405   IPI00974467   IPI01015660   IPI01015120   IPI00790602   IPI00974050   IPI00973860   IPI00981859   IPI01012335   IPI01012863   IPI00973742   
Protein Interaction databases
DIP (DOE-UCLA)Q6P1N9
IntAct (EBI)Q6P1N9
FunCoupENSG00000147687
BioGRIDTATDN1
STRING (EMBL)TATDN1
ZODIACTATDN1
Ontologies - Pathways
QuickGOQ6P1N9
Ontology : AmiGOdeoxyribonuclease activity  protein binding  nucleoplasm  DNA catabolic process  endodeoxyribonuclease activity, producing 5'-phosphomonoesters  metal ion binding  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBIdeoxyribonuclease activity  protein binding  nucleoplasm  DNA catabolic process  endodeoxyribonuclease activity, producing 5'-phosphomonoesters  metal ion binding  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkTATDN1
Atlas of Cancer Signalling NetworkTATDN1
Wikipedia pathwaysTATDN1
Orthology - Evolution
OrthoDB83940
GeneTree (enSembl)ENSG00000147687
Phylogenetic Trees/Animal Genes : TreeFamTATDN1
HOVERGENQ6P1N9
HOGENOMQ6P1N9
Homologs : HomoloGeneTATDN1
Homology/Alignments : Family Browser (UCSC)TATDN1
Gene fusions - Rearrangements
Fusion : MitelmanTATDN1/GSDMB [8q24.13/17q12]  
Fusion : MitelmanTATDN1/OC90 [8q24.13/8q24.22]  [t(8;8)(q24;q24)]  
Fusion: TCGATATDN1 8q24.13 OC90 8q24.22 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTATDN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TATDN1
dbVarTATDN1
ClinVarTATDN1
1000_GenomesTATDN1 
Exome Variant ServerTATDN1
ExAC (Exome Aggregation Consortium)TATDN1 (select the gene name)
Genetic variants : HAPMAP83940
Genomic Variants (DGV)TATDN1 [DGVbeta]
DECIPHER (Syndromes)8:125500735-125551329  ENSG00000147687
CONAN: Copy Number AnalysisTATDN1 
Mutations
ICGC Data PortalTATDN1 
TCGA Data PortalTATDN1 
Broad Tumor PortalTATDN1
OASIS PortalTATDN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTATDN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTATDN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TATDN1
DgiDB (Drug Gene Interaction Database)TATDN1
DoCM (Curated mutations)TATDN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TATDN1 (select a term)
intoGenTATDN1
Cancer3DTATDN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTATDN1
Genetic Testing Registry TATDN1
NextProtQ6P1N9 [Medical]
TSGene83940
GENETestsTATDN1
Huge Navigator TATDN1 [HugePedia]
snp3D : Map Gene to Disease83940
BioCentury BCIQTATDN1
ClinGenTATDN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83940
Chemical/Pharm GKB GenePA134971804
Clinical trialTATDN1
Miscellaneous
canSAR (ICR)TATDN1 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTATDN1
EVEXTATDN1
GoPubMedTATDN1
iHOPTATDN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:30:21 CET 2017

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