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TBC1D10C (TBC1 domain family member 10C)

Identity

Alias (NCBI)CARABIN
EPI64C
HGNC (Hugo) TBC1D10C
HGNC Alias symbFLJ00332
Carabin
EPI64C
HGNC Previous nameTBC1 domain family, member 10C
LocusID (NCBI) 374403
Atlas_Id 56225
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67403930 and ends at 67410089 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TBC1D10C   24702
Cards
Entrez_Gene (NCBI)TBC1D10C    TBC1 domain family member 10C
AliasesCARABIN; EPI64C
GeneCards (Weizmann)TBC1D10C
Ensembl hg19 (Hinxton)ENSG00000175463 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175463 [Gene_View]  ENSG00000175463 [Sequence]  chr11:67403930-67410089 [Contig_View]  TBC1D10C [Vega]
ICGC DataPortalENSG00000175463
TCGA cBioPortalTBC1D10C
AceView (NCBI)TBC1D10C
Genatlas (Paris)TBC1D10C
SOURCE (Princeton)TBC1D10C
Genetics Home Reference (NIH)TBC1D10C
Genomic and cartography
GoldenPath hg38 (UCSC)TBC1D10C  -     chr11:67403930-67410089 +  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBC1D10C  -     11q13.2   [Description]    (hg19-Feb_2009)
GoldenPathTBC1D10C - 11q13.2 [CytoView hg19]  TBC1D10C - 11q13.2 [CytoView hg38]
ImmunoBaseENSG00000175463
Genome Data Viewer NCBITBC1D10C [Mapview hg19]  
OMIM610831   
Gene and transcription
Genbank (Entrez)AK122585 AK126131 BC022202 BC035630 BC036873
RefSeq transcript (Entrez)NM_001256508 NM_001369492 NM_001369494 NM_001369495 NM_001369496 NM_001369497 NM_001369498 NM_198517
Consensus coding sequences : CCDS (NCBI)TBC1D10C
Gene ExpressionTBC1D10C [ NCBI-GEO ]   TBC1D10C [ EBI - ARRAY_EXPRESS ]   TBC1D10C [ SEEK ]   TBC1D10C [ MEM ]
Gene Expression Viewer (FireBrowse)TBC1D10C [ Firebrowse - Broad ]
GenevisibleExpression of TBC1D10C in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)374403
GTEX Portal (Tissue expression)TBC1D10C
Human Protein AtlasENSG00000175463-TBC1D10C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IV04   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IV04  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IV04
PhosPhoSitePlusQ8IV04
Domaine pattern : Prosite (Expaxy)TBC_RABGAP (PS50086)   
Domains : Interpro (EBI)Rab-GTPase-TBC_dom    Rab-GTPase_TBC_sf   
Domain families : Pfam (Sanger)RabGAP-TBC (PF00566)   
Domain families : Pfam (NCBI)pfam00566   
Domain families : Smart (EMBL)TBC (SM00164)  
Conserved Domain (NCBI)TBC1D10C
SuperfamilyQ8IV04
AlphaFold pdb e-kbQ8IV04   
Human Protein Atlas [tissue]ENSG00000175463-TBC1D10C [tissue]
HPRD13330
Protein Interaction databases
DIP (DOE-UCLA)Q8IV04
IntAct (EBI)Q8IV04
BioGRIDTBC1D10C
STRING (EMBL)TBC1D10C
ZODIACTBC1D10C
Ontologies - Pathways
QuickGOQ8IV04
Ontology : AmiGOGTPase activator activity  protein binding  cytosol  plasma membrane  plasma membrane  intracellular protein transport  membrane  filopodium membrane  retrograde transport, endosome to Golgi  neutrophil degranulation  negative regulation of B cell activation  negative regulation of ERK1 and ERK2 cascade  negative regulation of calcineurin-NFAT signaling cascade  activation of GTPase activity  ficolin-1-rich granule membrane  regulation of cilium assembly  
Ontology : EGO-EBIGTPase activator activity  protein binding  cytosol  plasma membrane  plasma membrane  intracellular protein transport  membrane  filopodium membrane  retrograde transport, endosome to Golgi  neutrophil degranulation  negative regulation of B cell activation  negative regulation of ERK1 and ERK2 cascade  negative regulation of calcineurin-NFAT signaling cascade  activation of GTPase activity  ficolin-1-rich granule membrane  regulation of cilium assembly  
NDEx NetworkTBC1D10C
Atlas of Cancer Signalling NetworkTBC1D10C
Wikipedia pathwaysTBC1D10C
Orthology - Evolution
OrthoDB374403
GeneTree (enSembl)ENSG00000175463
Phylogenetic Trees/Animal Genes : TreeFamTBC1D10C
Homologs : HomoloGeneTBC1D10C
Homology/Alignments : Family Browser (UCSC)TBC1D10C
Gene fusions - Rearrangements
Fusion : QuiverTBC1D10C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBC1D10C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBC1D10C
dbVarTBC1D10C
ClinVarTBC1D10C
MonarchTBC1D10C
1000_GenomesTBC1D10C 
Exome Variant ServerTBC1D10C
GNOMAD BrowserENSG00000175463
Varsome BrowserTBC1D10C
ACMGTBC1D10C variants
VarityQ8IV04
Genomic Variants (DGV)TBC1D10C [DGVbeta]
DECIPHERTBC1D10C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBC1D10C 
Mutations
ICGC Data PortalTBC1D10C 
TCGA Data PortalTBC1D10C 
Broad Tumor PortalTBC1D10C
OASIS PortalTBC1D10C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBC1D10C  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTBC1D10C
Mutations and Diseases : HGMDTBC1D10C
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTBC1D10C
DgiDB (Drug Gene Interaction Database)TBC1D10C
DoCM (Curated mutations)TBC1D10C
CIViC (Clinical Interpretations of Variants in Cancer)TBC1D10C
Cancer3DTBC1D10C
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610831   
Orphanet
DisGeNETTBC1D10C
MedgenTBC1D10C
Genetic Testing Registry TBC1D10C
NextProtQ8IV04 [Medical]
GENETestsTBC1D10C
Target ValidationTBC1D10C
Huge Navigator TBC1D10C [HugePedia]
ClinGenTBC1D10C
Clinical trials, drugs, therapy
MyCancerGenomeTBC1D10C
Protein Interactions : CTDTBC1D10C
Pharm GKB GenePA142670836
PharosQ8IV04
Clinical trialTBC1D10C
Miscellaneous
canSAR (ICR)TBC1D10C
HarmonizomeTBC1D10C
DataMed IndexTBC1D10C
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTBC1D10C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:20 CEST 2021

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