TBC1D16 (TBC1 domain family member 16)

2011-02-01  

Identity

HGNC
TBC1D16
LOCATION
17q25.3
LOCUSID
125058
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 125058
MIM: 616637
HGNC: 28356
Ensembl: ENSG00000167291

Variants:

dbSNP: 125058
ClinVar: 125058
TCGA: ENSG00000167291
COSMIC: TBC1D16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167291ENST00000310924Q8TBP0
ENSG00000167291ENST00000340848Q8TBP0
ENSG00000167291ENST00000570373I3L0V9
ENSG00000167291ENST00000571872I3L235
ENSG00000167291ENST00000572862Q8TBP0
ENSG00000167291ENST00000573782I3L4T6
ENSG00000167291ENST00000574241I3L4U4
ENSG00000167291ENST00000574427I3L0U9
ENSG00000167291ENST00000576768Q8TBP0

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
TBC/RABGAPsREACTOMER-HSA-8854214

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
211297712010An integrated approach to uncover drivers of cancer.213
260301782015Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.26
230193622012TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling.15
282766572017Investigation of correlations between DNA methylation, suicidal behavior and aging.4
299623802018Expression of TBC1D16 Is Associated with Favorable Prognosis of Epithelial Ovarian Cancer.0
313830002019Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types.0

Citation

Dessen P

TBC1D16 (TBC1 domain family member 16)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52050/tbc1d16