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TBC1D2B (TBC1 domain family member 2B)

Identity

Alias_namesTBC1 domain family
Alias_symbol (synonym)KIAA1055
Other alias-
HGNC (Hugo) TBC1D2B
LocusID (NCBI) 23102
Atlas_Id 56364
Location 15q24.3  [Link to chromosome band 15q24]
Location_base_pair Starts at 77994985 and ends at 78077652 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAM114A1 (4p14) / TBC1D2B (15q24.3)TBC1D2B (15q24.3) / PFKFB3 (10p15.1)TBC1D2B (15q24.3) / TBC1D2B (15q24.3)
TBC1D2B (15q24.3) / YIPF1 (1p32.3)THRAP3 (1p34.3) / TBC1D2B (15q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TBC1D2B   29183
Cards
Entrez_Gene (NCBI)TBC1D2B  23102  TBC1 domain family member 2B
Aliases
GeneCards (Weizmann)TBC1D2B
Ensembl hg19 (Hinxton)ENSG00000167202 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167202 [Gene_View]  chr15:77994985-78077652 [Contig_View]  TBC1D2B [Vega]
ICGC DataPortalENSG00000167202
TCGA cBioPortalTBC1D2B
AceView (NCBI)TBC1D2B
Genatlas (Paris)TBC1D2B
WikiGenes23102
SOURCE (Princeton)TBC1D2B
Genetics Home Reference (NIH)TBC1D2B
Genomic and cartography
GoldenPath hg38 (UCSC)TBC1D2B  -     chr15:77994985-78077652 -  15q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBC1D2B  -     15q24.3   [Description]    (hg19-Feb_2009)
EnsemblTBC1D2B - 15q24.3 [CytoView hg19]  TBC1D2B - 15q24.3 [CytoView hg38]
Mapping of homologs : NCBITBC1D2B [Mapview hg19]  TBC1D2B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB028978 AI432924 AK000173 AK074871 AL080229
RefSeq transcript (Entrez)NM_015079 NM_144572
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TBC1D2B
Cluster EST : UnigeneHs.567426 [ NCBI ]
CGAP (NCI)Hs.567426
Alternative Splicing GalleryENSG00000167202
Gene ExpressionTBC1D2B [ NCBI-GEO ]   TBC1D2B [ EBI - ARRAY_EXPRESS ]   TBC1D2B [ SEEK ]   TBC1D2B [ MEM ]
Gene Expression Viewer (FireBrowse)TBC1D2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23102
GTEX Portal (Tissue expression)TBC1D2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPU7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPU7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPU7
Splice isoforms : SwissVarQ9UPU7
PhosPhoSitePlusQ9UPU7
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    TBC_RABGAP (PS50086)   
Domains : Interpro (EBI)PH_dom-like    PH_domain    Rab-GTPase-TBC_dom   
Domain families : Pfam (Sanger)PH (PF00169)    RabGAP-TBC (PF00566)   
Domain families : Pfam (NCBI)pfam00169    pfam00566   
Domain families : Smart (EMBL)PH (SM00233)  TBC (SM00164)  
Conserved Domain (NCBI)TBC1D2B
DMDM Disease mutations23102
Blocks (Seattle)TBC1D2B
SuperfamilyQ9UPU7
Human Protein AtlasENSG00000167202
Peptide AtlasQ9UPU7
HPRD08310
IPIIPI00550733   IPI00879800   IPI00879627   IPI00916259   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPU7
IntAct (EBI)Q9UPU7
FunCoupENSG00000167202
BioGRIDTBC1D2B
STRING (EMBL)TBC1D2B
ZODIACTBC1D2B
Ontologies - Pathways
QuickGOQ9UPU7
Ontology : AmiGOGTPase activator activity  protein binding  intracellular  intracellular protein transport  endomembrane system  Rab GTPase binding  regulation of vesicle fusion  activation of GTPase activity  regulation of cilium assembly  
Ontology : EGO-EBIGTPase activator activity  protein binding  intracellular  intracellular protein transport  endomembrane system  Rab GTPase binding  regulation of vesicle fusion  activation of GTPase activity  regulation of cilium assembly  
NDEx NetworkTBC1D2B
Atlas of Cancer Signalling NetworkTBC1D2B
Wikipedia pathwaysTBC1D2B
Orthology - Evolution
OrthoDB23102
GeneTree (enSembl)ENSG00000167202
Phylogenetic Trees/Animal Genes : TreeFamTBC1D2B
HOVERGENQ9UPU7
HOGENOMQ9UPU7
Homologs : HomoloGeneTBC1D2B
Homology/Alignments : Family Browser (UCSC)TBC1D2B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBC1D2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBC1D2B
dbVarTBC1D2B
ClinVarTBC1D2B
1000_GenomesTBC1D2B 
Exome Variant ServerTBC1D2B
ExAC (Exome Aggregation Consortium)TBC1D2B (select the gene name)
Genetic variants : HAPMAP23102
Genomic Variants (DGV)TBC1D2B [DGVbeta]
DECIPHERTBC1D2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBC1D2B 
Mutations
ICGC Data PortalTBC1D2B 
TCGA Data PortalTBC1D2B 
Broad Tumor PortalTBC1D2B
OASIS PortalTBC1D2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBC1D2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTBC1D2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TBC1D2B
DgiDB (Drug Gene Interaction Database)TBC1D2B
DoCM (Curated mutations)TBC1D2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TBC1D2B (select a term)
intoGenTBC1D2B
Cancer3DTBC1D2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTBC1D2B
Genetic Testing Registry TBC1D2B
NextProtQ9UPU7 [Medical]
TSGene23102
GENETestsTBC1D2B
Target ValidationTBC1D2B
Huge Navigator TBC1D2B [HugePedia]
snp3D : Map Gene to Disease23102
BioCentury BCIQTBC1D2B
ClinGenTBC1D2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23102
Chemical/Pharm GKB GenePA142670832
Clinical trialTBC1D2B
Miscellaneous
canSAR (ICR)TBC1D2B (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTBC1D2B
EVEXTBC1D2B
GoPubMedTBC1D2B
iHOPTBC1D2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:58:40 CEST 2017

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