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TBC1D2B (TBC1 domain family member 2B)

Identity

Alias (NCBI)NEDSGO
HGNC (Hugo) TBC1D2B
HGNC Alias symbKIAA1055
HGNC Previous nameTBC1 domain family, member 2B
LocusID (NCBI) 23102
Atlas_Id 56364
Location 15q24.3  [Link to chromosome band 15q24]
Location_base_pair Starts at 77994985 and ends at 78077652 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAM114A1 (4p14) / TBC1D2B (15q24.3)TBC1D2B (15q24.3) / PFKFB3 (10p15.1)TBC1D2B (15q24.3) / TBC1D2B (15q24.3)
TBC1D2B (15q24.3) / YIPF1 (1p32.3)THRAP3 (1p34.3) / TBC1D2B (15q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TBC1D2B   29183
Cards
Entrez_Gene (NCBI)TBC1D2B    TBC1 domain family member 2B
AliasesNEDSGO
GeneCards (Weizmann)TBC1D2B
Ensembl hg19 (Hinxton)ENSG00000167202 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167202 [Gene_View]  ENSG00000167202 [Sequence]  chr15:77994985-78077652 [Contig_View]  TBC1D2B [Vega]
ICGC DataPortalENSG00000167202
TCGA cBioPortalTBC1D2B
AceView (NCBI)TBC1D2B
Genatlas (Paris)TBC1D2B
SOURCE (Princeton)TBC1D2B
Genetics Home Reference (NIH)TBC1D2B
Genomic and cartography
GoldenPath hg38 (UCSC)TBC1D2B  -     chr15:77994985-78077652 -  15q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBC1D2B  -     15q24.3   [Description]    (hg19-Feb_2009)
GoldenPathTBC1D2B - 15q24.3 [CytoView hg19]  TBC1D2B - 15q24.3 [CytoView hg38]
ImmunoBaseENSG00000167202
Genome Data Viewer NCBITBC1D2B [Mapview hg19]  
OMIM619152   619323   
Gene and transcription
Genbank (Entrez)AB028978 AI432924 AK000173 AK074871 AL080229
RefSeq transcript (Entrez)NM_001387142 NM_001387143 NM_001387144 NM_001387145 NM_001387146 NM_001387147 NM_001387148 NM_001387149 NM_015079 NM_144572
Consensus coding sequences : CCDS (NCBI)TBC1D2B
Gene ExpressionTBC1D2B [ NCBI-GEO ]   TBC1D2B [ EBI - ARRAY_EXPRESS ]   TBC1D2B [ SEEK ]   TBC1D2B [ MEM ]
Gene Expression Viewer (FireBrowse)TBC1D2B [ Firebrowse - Broad ]
GenevisibleExpression of TBC1D2B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23102
GTEX Portal (Tissue expression)TBC1D2B
Human Protein AtlasENSG00000167202-TBC1D2B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPU7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPU7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPU7
PhosPhoSitePlusQ9UPU7
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    TBC_RABGAP (PS50086)   
Domains : Interpro (EBI)PH-like_dom_sf    PH_domain    Rab-GTPase-TBC_dom    Rab-GTPase_TBC_sf   
Domain families : Pfam (Sanger)PH (PF00169)    RabGAP-TBC (PF00566)   
Domain families : Pfam (NCBI)pfam00169    pfam00566   
Domain families : Smart (EMBL)PH (SM00233)  TBC (SM00164)  
Conserved Domain (NCBI)TBC1D2B
SuperfamilyQ9UPU7
AlphaFold pdb e-kbQ9UPU7   
Human Protein Atlas [tissue]ENSG00000167202-TBC1D2B [tissue]
HPRD08310
Protein Interaction databases
DIP (DOE-UCLA)Q9UPU7
IntAct (EBI)Q9UPU7
BioGRIDTBC1D2B
STRING (EMBL)TBC1D2B
ZODIACTBC1D2B
Ontologies - Pathways
QuickGOQ9UPU7
Ontology : AmiGOGTPase activator activity  protein binding  cytosol  intracellular protein transport  activation of GTPase activity  regulation of cilium assembly  
Ontology : EGO-EBIGTPase activator activity  protein binding  cytosol  intracellular protein transport  activation of GTPase activity  regulation of cilium assembly  
NDEx NetworkTBC1D2B
Atlas of Cancer Signalling NetworkTBC1D2B
Wikipedia pathwaysTBC1D2B
Orthology - Evolution
OrthoDB23102
GeneTree (enSembl)ENSG00000167202
Phylogenetic Trees/Animal Genes : TreeFamTBC1D2B
Homologs : HomoloGeneTBC1D2B
Homology/Alignments : Family Browser (UCSC)TBC1D2B
Gene fusions - Rearrangements
Fusion : QuiverTBC1D2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBC1D2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBC1D2B
dbVarTBC1D2B
ClinVarTBC1D2B
MonarchTBC1D2B
1000_GenomesTBC1D2B 
Exome Variant ServerTBC1D2B
GNOMAD BrowserENSG00000167202
Varsome BrowserTBC1D2B
ACMGTBC1D2B variants
VarityQ9UPU7
Genomic Variants (DGV)TBC1D2B [DGVbeta]
DECIPHERTBC1D2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBC1D2B 
Mutations
ICGC Data PortalTBC1D2B 
TCGA Data PortalTBC1D2B 
Broad Tumor PortalTBC1D2B
OASIS PortalTBC1D2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBC1D2B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTBC1D2B
Mutations and Diseases : HGMDTBC1D2B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTBC1D2B
DgiDB (Drug Gene Interaction Database)TBC1D2B
DoCM (Curated mutations)TBC1D2B
CIViC (Clinical Interpretations of Variants in Cancer)TBC1D2B
Cancer3DTBC1D2B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM619152    619323   
Orphanet
DisGeNETTBC1D2B
MedgenTBC1D2B
Genetic Testing Registry TBC1D2B
NextProtQ9UPU7 [Medical]
GENETestsTBC1D2B
Target ValidationTBC1D2B
Huge Navigator TBC1D2B [HugePedia]
ClinGenTBC1D2B
Clinical trials, drugs, therapy
MyCancerGenomeTBC1D2B
Protein Interactions : CTDTBC1D2B
Pharm GKB GenePA142670832
PharosQ9UPU7
Clinical trialTBC1D2B
Miscellaneous
canSAR (ICR)TBC1D2B
HarmonizomeTBC1D2B
DataMed IndexTBC1D2B
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTBC1D2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:23 CEST 2021

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