Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TBCC (tubulin folding cofactor C)

Identity

Alias_namestubulin-specific chaperone c
Alias_symbol (synonym)CFC
Other alias
HGNC (Hugo) TBCC
LocusID (NCBI) 6903
Atlas_Id 42478
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 42744496 and ends at 42746146 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ISG20 (15q26.1) / TBCC (6p21.1)TBCC (6p21.1) / ELMO1 (7p14.2)TBCC (6p21.1) / TNFRSF12A (16p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TBCC   11580
Cards
Entrez_Gene (NCBI)TBCC  6903  tubulin folding cofactor C
AliasesCFC
GeneCards (Weizmann)TBCC
Ensembl hg19 (Hinxton)ENSG00000124659 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124659 [Gene_View]  ENSG00000124659 [Sequence]  chr6:42744496-42746146 [Contig_View]  TBCC [Vega]
ICGC DataPortalENSG00000124659
TCGA cBioPortalTBCC
AceView (NCBI)TBCC
Genatlas (Paris)TBCC
WikiGenes6903
SOURCE (Princeton)TBCC
Genetics Home Reference (NIH)TBCC
Genomic and cartography
GoldenPath hg38 (UCSC)TBCC  -     chr6:42744496-42746146 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBCC  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblTBCC - 6p21.1 [CytoView hg19]  TBCC - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBITBCC [Mapview hg19]  TBCC [Mapview hg38]
OMIM602971   
Gene and transcription
Genbank (Entrez)AK312681 BC017479 BC020170 BE795945 BT007002
RefSeq transcript (Entrez)NM_003192
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TBCC
Cluster EST : UnigeneHs.75064 [ NCBI ]
CGAP (NCI)Hs.75064
Alternative Splicing GalleryENSG00000124659
Gene ExpressionTBCC [ NCBI-GEO ]   TBCC [ EBI - ARRAY_EXPRESS ]   TBCC [ SEEK ]   TBCC [ MEM ]
Gene Expression Viewer (FireBrowse)TBCC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6903
GTEX Portal (Tissue expression)TBCC
Human Protein AtlasENSG00000124659-TBCC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15814   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15814  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15814
Splice isoforms : SwissVarQ15814
PhosPhoSitePlusQ15814
Domaine pattern : Prosite (Expaxy)C_CAP_COFACTOR_C (PS51329)   
Domains : Interpro (EBI)C-CAP_CF_C-like    CAP/MinC_C    CARP_motif    TBCC    TBCC_N    TBCC_N_sf    Tubulin-bd_cofactor_C_dom   
Domain families : Pfam (Sanger)TBCC (PF07986)    TBCC_N (PF16752)   
Domain families : Pfam (NCBI)pfam07986    pfam16752   
Domain families : Smart (EMBL)CARP (SM00673)  
Conserved Domain (NCBI)TBCC
DMDM Disease mutations6903
Blocks (Seattle)TBCC
PDB (SRS)2L3L    2YUH   
PDB (PDBSum)2L3L    2YUH   
PDB (IMB)2L3L    2YUH   
PDB (RSDB)2L3L    2YUH   
Structural Biology KnowledgeBase2L3L    2YUH   
SCOP (Structural Classification of Proteins)2L3L    2YUH   
CATH (Classification of proteins structures)2L3L    2YUH   
SuperfamilyQ15814
Human Protein Atlas [tissue]ENSG00000124659-TBCC [tissue]
Peptide AtlasQ15814
HPRD04276
IPIIPI00019924   
Protein Interaction databases
DIP (DOE-UCLA)Q15814
IntAct (EBI)Q15814
FunCoupENSG00000124659
BioGRIDTBCC
STRING (EMBL)TBCC
ZODIACTBCC
Ontologies - Pathways
QuickGOQ15814
Ontology : AmiGOcell morphogenesis  GTPase activity  cytoplasm  cytoplasm  cytosol  cytoskeleton  microtubule  protein folding  protein folding  tubulin complex assembly  post-chaperonin tubulin folding pathway  tubulin binding  photoreceptor connecting cilium  chaperone binding  
Ontology : EGO-EBIcell morphogenesis  GTPase activity  cytoplasm  cytoplasm  cytosol  cytoskeleton  microtubule  protein folding  protein folding  tubulin complex assembly  post-chaperonin tubulin folding pathway  tubulin binding  photoreceptor connecting cilium  chaperone binding  
NDEx NetworkTBCC
Atlas of Cancer Signalling NetworkTBCC
Wikipedia pathwaysTBCC
Orthology - Evolution
OrthoDB6903
GeneTree (enSembl)ENSG00000124659
Phylogenetic Trees/Animal Genes : TreeFamTBCC
HOVERGENQ15814
HOGENOMQ15814
Homologs : HomoloGeneTBCC
Homology/Alignments : Family Browser (UCSC)TBCC
Gene fusions - Rearrangements
Fusion : QuiverTBCC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBCC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBCC
dbVarTBCC
ClinVarTBCC
1000_GenomesTBCC 
Exome Variant ServerTBCC
ExAC (Exome Aggregation Consortium)ENSG00000124659
GNOMAD BrowserENSG00000124659
Varsome BrowserTBCC
Genetic variants : HAPMAP6903
Genomic Variants (DGV)TBCC [DGVbeta]
DECIPHERTBCC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBCC 
Mutations
ICGC Data PortalTBCC 
TCGA Data PortalTBCC 
Broad Tumor PortalTBCC
OASIS PortalTBCC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBCC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTBCC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TBCC
DgiDB (Drug Gene Interaction Database)TBCC
DoCM (Curated mutations)TBCC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TBCC (select a term)
intoGenTBCC
Cancer3DTBCC(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602971   
Orphanet
DisGeNETTBCC
MedgenTBCC
Genetic Testing Registry TBCC
NextProtQ15814 [Medical]
TSGene6903
GENETestsTBCC
Target ValidationTBCC
Huge Navigator TBCC [HugePedia]
snp3D : Map Gene to Disease6903
BioCentury BCIQTBCC
ClinGenTBCC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6903
Chemical/Pharm GKB GenePA36344
Clinical trialTBCC
Miscellaneous
canSAR (ICR)TBCC (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTBCC
EVEXTBCC
GoPubMedTBCC
iHOPTBCC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:43:59 CET 2018

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