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TBCEL (tubulin folding cofactor E like)

Identity

Alias_namesLRRC35
leucine rich repeat containing 35
tubulin-specific chaperone e-like
Alias_symbol (synonym)MGC10233
Other aliasEl
HGNC (Hugo) TBCEL
LocusID (NCBI) 219899
Atlas_Id 54016
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 121024072 and ends at 121090776 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MRPL18 (6q25.3) / TBCEL (11q23.3)SORL1 (11q24.1) / TBCEL (11q23.3)TBCEL (11q23.3) / TECTA (11q23.3)
TECTA (11q23.3) / TBCEL (11q23.3)TECTA TBCELSORL1 11q24.1 / TBCEL 11q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;11)(q23;q24) SORL1/TBCEL


External links

Nomenclature
HGNC (Hugo)TBCEL   28115
Cards
Entrez_Gene (NCBI)TBCEL  219899  tubulin folding cofactor E like
AliasesEl; LRRC35
GeneCards (Weizmann)TBCEL
Ensembl hg19 (Hinxton)ENSG00000154114 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154114 [Gene_View]  ENSG00000154114 [Sequence]  chr11:121024072-121090776 [Contig_View]  TBCEL [Vega]
ICGC DataPortalENSG00000154114
TCGA cBioPortalTBCEL
AceView (NCBI)TBCEL
Genatlas (Paris)TBCEL
WikiGenes219899
SOURCE (Princeton)TBCEL
Genetics Home Reference (NIH)TBCEL
Genomic and cartography
GoldenPath hg38 (UCSC)TBCEL  -     chr11:121024072-121090776 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBCEL  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblTBCEL - 6p21.1 [CytoView hg19]  TBCEL - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBITBCEL [Mapview hg19]  TBCEL [Mapview hg38]
OMIM610451   
Gene and transcription
Genbank (Entrez)AA806611 AI128257 AK024239 AK095817 AK295673
RefSeq transcript (Entrez)NM_001130047 NM_001363644 NM_152715
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TBCEL
Cluster EST : UnigeneHs.720282 [ NCBI ]
CGAP (NCI)Hs.720282
Alternative Splicing GalleryENSG00000154114
Gene ExpressionTBCEL [ NCBI-GEO ]   TBCEL [ EBI - ARRAY_EXPRESS ]   TBCEL [ SEEK ]   TBCEL [ MEM ]
Gene Expression Viewer (FireBrowse)TBCEL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)219899
GTEX Portal (Tissue expression)TBCEL
Human Protein AtlasENSG00000154114-TBCEL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5QJ74   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5QJ74  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5QJ74
Splice isoforms : SwissVarQ5QJ74
PhosPhoSitePlusQ5QJ74
Domaine pattern : Prosite (Expaxy)UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)LRR_dom_sf    Ubiquitin-like_domsf    Ubiquitin_dom   
Domain families : Pfam (Sanger)Ubiquitin_2 (PF14560)   
Domain families : Pfam (NCBI)pfam14560   
Conserved Domain (NCBI)TBCEL
DMDM Disease mutations219899
Blocks (Seattle)TBCEL
SuperfamilyQ5QJ74
Human Protein Atlas [tissue]ENSG00000154114-TBCEL [tissue]
Peptide AtlasQ5QJ74
HPRD11302
IPIIPI00166956   IPI00910784   IPI00973870   IPI00902999   IPI00980351   IPI00982328   IPI00981498   
Protein Interaction databases
DIP (DOE-UCLA)Q5QJ74
IntAct (EBI)Q5QJ74
FunCoupENSG00000154114
BioGRIDTBCEL
STRING (EMBL)TBCEL
ZODIACTBCEL
Ontologies - Pathways
QuickGOQ5QJ74
Ontology : AmiGOprotein binding  cytoplasm  cytoskeleton  
Ontology : EGO-EBIprotein binding  cytoplasm  cytoskeleton  
NDEx NetworkTBCEL
Atlas of Cancer Signalling NetworkTBCEL
Wikipedia pathwaysTBCEL
Orthology - Evolution
OrthoDB219899
GeneTree (enSembl)ENSG00000154114
Phylogenetic Trees/Animal Genes : TreeFamTBCEL
HOVERGENQ5QJ74
HOGENOMQ5QJ74
Homologs : HomoloGeneTBCEL
Homology/Alignments : Family Browser (UCSC)TBCEL
Gene fusions - Rearrangements
Fusion : MitelmanSORL1/TBCEL [11q24.1/11q23.3]  [t(11;11)(q23;q24)]  
Fusion PortalSORL1 11q24.1 TBCEL 11q23.3 OV
Fusion : QuiverTBCEL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBCEL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBCEL
dbVarTBCEL
ClinVarTBCEL
1000_GenomesTBCEL 
Exome Variant ServerTBCEL
ExAC (Exome Aggregation Consortium)ENSG00000154114
GNOMAD BrowserENSG00000154114
Varsome BrowserTBCEL
Genetic variants : HAPMAP219899
Genomic Variants (DGV)TBCEL [DGVbeta]
DECIPHERTBCEL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBCEL 
Mutations
ICGC Data PortalTBCEL 
TCGA Data PortalTBCEL 
Broad Tumor PortalTBCEL
OASIS PortalTBCEL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBCEL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTBCEL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TBCEL
DgiDB (Drug Gene Interaction Database)TBCEL
DoCM (Curated mutations)TBCEL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TBCEL (select a term)
intoGenTBCEL
Cancer3DTBCEL(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610451   
Orphanet
DisGeNETTBCEL
MedgenTBCEL
Genetic Testing Registry TBCEL
NextProtQ5QJ74 [Medical]
TSGene219899
GENETestsTBCEL
Target ValidationTBCEL
Huge Navigator TBCEL [HugePedia]
snp3D : Map Gene to Disease219899
BioCentury BCIQTBCEL
ClinGenTBCEL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD219899
Chemical/Pharm GKB GenePA162405374
Clinical trialTBCEL
Miscellaneous
canSAR (ICR)TBCEL (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTBCEL
EVEXTBCEL
GoPubMedTBCEL
iHOPTBCEL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Aug 16 11:36:20 CEST 2018

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