| Nomenclature |
|---|
| HGNC (Hugo) | TBP 11588 |
| Cards |
|---|
| Entrez_Gene (NCBI) | TBP 6908 TATA-box binding protein |
| Aliases | GTF2D; GTF2D1; HDL4; SCA17; |
| TFIID |
| GeneCards (Weizmann) | TBP |
| Ensembl hg19 (Hinxton) | ENSG00000112592 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000112592 [Gene_View] ENSG00000112592 [Sequence] chr6:170554333-170572870 [Contig_View] TBP [Vega] |
| ICGC DataPortal | ENSG00000112592 |
| TCGA cBioPortal | TBP |
| AceView (NCBI) | TBP |
| Genatlas (Paris) | TBP |
| WikiGenes | 6908 |
| SOURCE (Princeton) | TBP |
| Genetics Home Reference (NIH) | TBP |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | TBP - chr6:170554333-170572870 + 6q27 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | TBP - 6q27 [Description] (hg19-Feb_2009) |
| Ensembl | TBP - 6q27 [CytoView hg19] TBP - 6q27 [CytoView hg38] |
| Mapping of homologs : NCBI | TBP [Mapview hg19] TBP [Mapview hg38] |
| OMIM | 168600 600075 607136 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK298272 AK304648 AK315222 BC109053 BC109054 |
| RefSeq transcript (Entrez) | NM_001172085 NM_003194 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | TBP |
| Cluster EST : Unigene | Hs.590872 [ NCBI ] |
| CGAP (NCI) | Hs.590872 |
| Alternative Splicing Gallery | ENSG00000112592 |
| Gene Expression | TBP [ NCBI-GEO ] TBP [ EBI - ARRAY_EXPRESS ]
TBP [ SEEK ] TBP [ MEM ] |
| Gene Expression Viewer (FireBrowse) | TBP [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 6908 |
| GTEX Portal (Tissue expression) | TBP |
| Human Protein Atlas | ENSG00000112592-TBP [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P20226 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P20226 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P20226 |
| Splice isoforms : SwissVar | P20226 |
| PhosPhoSitePlus | P20226 |
| Domaine pattern : Prosite (Expaxy) | TFIID (PS00351) |
| Domains : Interpro (EBI) | TBP TBP_CS TBP_dom_sf TBP_eukaryotic |
| Domain families : Pfam (Sanger) | TBP (PF00352) |
| Domain families : Pfam (NCBI) | pfam00352 |
| Conserved Domain (NCBI) | TBP |
| DMDM Disease mutations | 6908 |
| Blocks (Seattle) | TBP |
| PDB (SRS) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G |
| PDB (PDBSum) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G |
| PDB (IMB) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G |
| PDB (RSDB) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G |
| Structural Biology KnowledgeBase | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G |
| SCOP (Structural Classification of Proteins) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G |
| CATH (Classification of proteins structures) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G |
| Superfamily | P20226 |
| Human Protein Atlas [tissue] | ENSG00000112592-TBP [tissue] |
| Peptide Atlas | P20226 |
| HPRD | 02511 |
| IPI | IPI00022831 IPI00910049 IPI01025146 IPI00640595 IPI00956126 IPI00645617 IPI00641088 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P20226 |
| IntAct (EBI) | P20226 |
| FunCoup | ENSG00000112592 |
| BioGRID | TBP |
| STRING (EMBL) | TBP |
| ZODIAC | TBP |
| Ontologies - Pathways |
|---|
| QuickGO | P20226 |
| Ontology : AmiGO | transcription factor TFIIIB complex nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific proximal promoter sequence-specific DNA binding RNA polymerase III general transcription initiation factor activity RNA polymerase III regulatory region DNA binding core promoter binding TFIIB-class transcription factor binding RNA polymerase II repressing transcription factor binding female pronucleus male pronucleus DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm transcription factor complex transcription factor TFIID complex transcription factor TFIID complex transcription factor TFIIA complex nuclear euchromatin cytoplasm regulation of transcription by RNA polymerase II transcription initiation from RNA polymerase I promoter termination of RNA polymerase I transcription transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter transcription by RNA polymerase III transcription by RNA polymerase III spermatogenesis transcription factor binding transcription factor binding viral process RNA polymerase II general transcription initiation factor activity aryl hydrocarbon receptor binding enzyme binding protein-containing complex snRNA transcription by RNA polymerase II transcription regulatory region DNA binding positive regulation of gene expression, epigenetic positive regulation of transcription, DNA-templated RNA polymerase II preinitiation complex assembly repressing transcription factor binding RNA polymerase III preinitiation complex assembly transcriptional preinitiation complex regulation of signal transduction by p53 class mediator |
| Ontology : EGO-EBI | transcription factor TFIIIB complex nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific proximal promoter sequence-specific DNA binding RNA polymerase III general transcription initiation factor activity RNA polymerase III regulatory region DNA binding core promoter binding TFIIB-class transcription factor binding RNA polymerase II repressing transcription factor binding female pronucleus male pronucleus DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm transcription factor complex transcription factor TFIID complex transcription factor TFIID complex transcription factor TFIIA complex nuclear euchromatin cytoplasm regulation of transcription by RNA polymerase II transcription initiation from RNA polymerase I promoter termination of RNA polymerase I transcription transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter transcription by RNA polymerase III transcription by RNA polymerase III spermatogenesis transcription factor binding transcription factor binding viral process RNA polymerase II general transcription initiation factor activity aryl hydrocarbon receptor binding enzyme binding protein-containing complex snRNA transcription by RNA polymerase II transcription regulatory region DNA binding positive regulation of gene expression, epigenetic positive regulation of transcription, DNA-templated RNA polymerase II preinitiation complex assembly repressing transcription factor binding RNA polymerase III preinitiation complex assembly transcriptional preinitiation complex regulation of signal transduction by p53 class mediator |
| Pathways : KEGG | Basal transcription factors Huntington's disease HTLV-I infection Herpes simplex infection Epstein-Barr virus infection Viral carcinogenesis |
| NDEx Network | TBP |
| Atlas of Cancer Signalling Network | TBP |
| Wikipedia pathways | TBP |
| Orthology - Evolution |
|---|
| OrthoDB | 6908 |
| GeneTree (enSembl) | ENSG00000112592 |
| Phylogenetic Trees/Animal Genes : TreeFam | TBP |
| HOVERGEN | P20226 |
| HOGENOM | P20226 |
| Homologs : HomoloGene | TBP |
| Homology/Alignments : Family Browser (UCSC) | TBP |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | TBP |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | TBP [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | TBP |
| dbVar | TBP |
| ClinVar | TBP |
| 1000_Genomes | TBP |
| Exome Variant Server | TBP |
| ExAC (Exome Aggregation Consortium) | ENSG00000112592 |
| GNOMAD Browser | ENSG00000112592 |
| Varsome Browser | TBP |
| Genetic variants : HAPMAP | 6908 |
| Genomic Variants (DGV) | TBP [DGVbeta] |
| DECIPHER | TBP [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | TBP |
| Mutations |
|---|
| ICGC Data Portal | TBP |
| TCGA Data Portal | TBP |
| Broad Tumor Portal | TBP |
| OASIS Portal | TBP [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | TBP [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | TBP |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search TBP |
| DgiDB (Drug Gene Interaction Database) | TBP |
| DoCM (Curated mutations) | TBP (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | TBP (select a term) |
| intoGen | TBP |
| Cancer3D | TBP(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 168600 600075 607136 |
| Orphanet | 13776 |
| DisGeNET | TBP |
| Medgen | TBP |
| Genetic Testing Registry | TBP
|
| NextProt | P20226 [Medical] |
| TSGene | 6908 |
| GENETests | TBP |
| Target Validation | TBP |
| Huge Navigator |
TBP [HugePedia] |
| snp3D : Map Gene to Disease | 6908 |
| BioCentury BCIQ | TBP |
| ClinGen | TBP |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 6908 |
| Chemical/Pharm GKB Gene | PA36352 |
| Clinical trial | TBP |
| Miscellaneous |
|---|
| canSAR (ICR) | TBP (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 364 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | TBP |
| EVEX | TBP |
| GoPubMed | TBP |
| iHOP | TBP |
