| Nomenclature |
|---|
| HGNC (Hugo) | TBP 11588 |
| Cards |
|---|
| Entrez_Gene (NCBI) | TBP TATA-box binding protein |
| Aliases | GTF2D; GTF2D1; HDL4; SCA17; |
| TFIID |
| GeneCards (Weizmann) | TBP |
| Ensembl hg19 (Hinxton) | ENSG00000112592 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000112592 [Gene_View] ENSG00000112592 [Sequence] chr6:170554369-170572859 [Contig_View] TBP [Vega] |
| ICGC DataPortal | ENSG00000112592 |
| TCGA cBioPortal | TBP |
| AceView (NCBI) | TBP |
| Genatlas (Paris) | TBP |
| SOURCE (Princeton) | TBP |
| Genetics Home Reference (NIH) | TBP |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | TBP - chr6:170554369-170572859 + 6q27 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | TBP - 6q27 [Description] (hg19-Feb_2009) |
| GoldenPath | TBP - 6q27 [CytoView hg19] TBP - 6q27 [CytoView hg38] |
| ImmunoBase | ENSG00000112592 |
| Genome Data Viewer NCBI | TBP [Mapview hg19] |
| OMIM | 168600 600075 607136 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK298272 AK304648 AK315222 BC109053 BC109054 |
| RefSeq transcript (Entrez) | NM_001172085 NM_003194 |
| Consensus coding sequences : CCDS (NCBI) | TBP |
| Gene Expression | TBP [ NCBI-GEO ] TBP [ EBI - ARRAY_EXPRESS ]
TBP [ SEEK ] TBP [ MEM ] |
| Gene Expression Viewer (FireBrowse) | TBP [ Firebrowse - Broad ] |
| Genevisible | Expression of TBP in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 6908 |
| GTEX Portal (Tissue expression) | TBP |
| Human Protein Atlas | ENSG00000112592-TBP [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P20226 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P20226 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P20226 |
| PhosPhoSitePlus | P20226 |
| Domaine pattern : Prosite (Expaxy) | TFIID (PS00351) |
| Domains : Interpro (EBI) | TBP TBP_CS TBP_dom_sf TBP_eukaryotic |
| Domain families : Pfam (Sanger) | TBP (PF00352) |
| Domain families : Pfam (NCBI) | pfam00352 |
| Conserved Domain (NCBI) | TBP |
| PDB (RSDB) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L |
| PDB Europe | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L |
| PDB (PDBSum) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L |
| PDB (IMB) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L |
| Structural Biology KnowledgeBase | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L |
| SCOP (Structural Classification of Proteins) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L |
| CATH (Classification of proteins structures) | 1C9B 1CDW 1JFI 1NVP 1TGH 4ROC 4ROD 4ROE 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5N9G 6MZD 6MZL 6MZM 6O9L |
| Superfamily | P20226 |
| AlphaFold pdb e-kb | P20226 |
| Human Protein Atlas [tissue] | ENSG00000112592-TBP [tissue] |
| HPRD | 02511 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P20226 |
| IntAct (EBI) | P20226 |
| BioGRID | TBP |
| STRING (EMBL) | TBP |
| ZODIAC | TBP |
| Ontologies - Pathways |
|---|
| QuickGO | P20226 |
| Ontology : AmiGO | chromatin euchromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase III general transcription initiation factor activity core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor binding TFIIB-class transcription factor binding female pronucleus male pronucleus protein binding nucleus nucleoplasm nucleoplasm transcription factor TFIID complex transcription factor TFIIA complex cytoplasm DNA-templated transcription, initiation transcription initiation from RNA polymerase I promoter termination of RNA polymerase I transcription transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter transcription by RNA polymerase III transcription by RNA polymerase III spermatogenesis transcription factor binding RNA polymerase II general transcription initiation factor activity RNA polymerase II general transcription initiation factor activity aryl hydrocarbon receptor binding enzyme binding protein-containing complex snRNA transcription by RNA polymerase II positive regulation of gene expression, epigenetic positive regulation of transcription, DNA-templated RNA polymerase II preinitiation complex assembly transcription preinitiation complex general transcription initiation factor activity DNA-binding transcription factor binding regulation of signal transduction by p53 class mediator |
| Ontology : EGO-EBI | chromatin euchromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase III general transcription initiation factor activity core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor binding TFIIB-class transcription factor binding female pronucleus male pronucleus protein binding nucleus nucleoplasm nucleoplasm transcription factor TFIID complex transcription factor TFIIA complex cytoplasm DNA-templated transcription, initiation transcription initiation from RNA polymerase I promoter termination of RNA polymerase I transcription transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter transcription by RNA polymerase III transcription by RNA polymerase III spermatogenesis transcription factor binding RNA polymerase II general transcription initiation factor activity RNA polymerase II general transcription initiation factor activity aryl hydrocarbon receptor binding enzyme binding protein-containing complex snRNA transcription by RNA polymerase II positive regulation of gene expression, epigenetic positive regulation of transcription, DNA-templated RNA polymerase II preinitiation complex assembly transcription preinitiation complex general transcription initiation factor activity DNA-binding transcription factor binding regulation of signal transduction by p53 class mediator |
| Pathways : BIOCARTA | RNA polymerase III transcription [Genes] Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells [Genes] CARM1 and Regulation of the Estrogen Receptor [Genes] Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes [Genes] |
| Pathways : KEGG | Basal transcription factors Huntington's disease HTLV-I infection Herpes simplex infection Epstein-Barr virus infection Viral carcinogenesis |
| NDEx Network | TBP |
| Atlas of Cancer Signalling Network | TBP |
| Wikipedia pathways | TBP |
| Orthology - Evolution |
|---|
| OrthoDB | 6908 |
| GeneTree (enSembl) | ENSG00000112592 |
| Phylogenetic Trees/Animal Genes : TreeFam | TBP |
| Homologs : HomoloGene | TBP |
| Homology/Alignments : Family Browser (UCSC) | TBP |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | TBP |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | TBP [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | TBP |
| dbVar | TBP |
| ClinVar | TBP |
| Monarch | TBP |
| 1000_Genomes | TBP |
| Exome Variant Server | TBP |
| GNOMAD Browser | ENSG00000112592 |
| Varsome Browser | TBP |
| ACMG | TBP variants |
| Varity | P20226 |
| Genomic Variants (DGV) | TBP [DGVbeta] |
| DECIPHER | TBP [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | TBP |
| Mutations |
|---|
| ICGC Data Portal | TBP |
| TCGA Data Portal | TBP |
| Broad Tumor Portal | TBP |
| OASIS Portal | TBP [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | TBP [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | TBP |
| Mutations and Diseases : HGMD | TBP |
| LOVD (Leiden Open Variation Database) | [gene] [transcripts] [variants] |
| BioMuta | TBP |
| DgiDB (Drug Gene Interaction Database) | TBP |
| DoCM (Curated mutations) | TBP |
| CIViC (Clinical Interpretations of Variants in Cancer) | TBP |
| Cancer3D | TBP |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 168600 600075 607136 |
| Orphanet | 13776 |
| DisGeNET | TBP |
| Medgen | TBP |
| Genetic Testing Registry | TBP
|
| NextProt | P20226 [Medical] |
| GENETests | TBP |
| Target Validation | TBP |
| Huge Navigator |
TBP [HugePedia] |
| ClinGen | TBP |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | TBP |
| Protein Interactions : CTD | TBP |
| Pharm GKB Gene | PA36352 |
| Pharos | P20226 |
| Clinical trial | TBP |
| Miscellaneous |
|---|
| canSAR (ICR) | TBP |
| Harmonizome | TBP |
| DataMed Index | TBP |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 389 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | TBP |
