Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TBP (TATA-box binding protein)

Identity

Alias_namesGTF2D1
SCA17
Alias_symbol (synonym)TFIID
Other aliasGTF2D
HDL4
HGNC (Hugo) TBP
LocusID (NCBI) 6908
Atlas_Id 42481
Location 6q27  [Link to chromosome band 6q27]
Location_base_pair Starts at 170554333 and ends at 170572870 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TBP   11588
Cards
Entrez_Gene (NCBI)TBP  6908  TATA-box binding protein
AliasesGTF2D; GTF2D1; HDL4; SCA17; 
TFIID
GeneCards (Weizmann)TBP
Ensembl hg19 (Hinxton)ENSG00000112592 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112592 [Gene_View]  ENSG00000112592 [Sequence]  chr6:170554333-170572870 [Contig_View]  TBP [Vega]
ICGC DataPortalENSG00000112592
TCGA cBioPortalTBP
AceView (NCBI)TBP
Genatlas (Paris)TBP
WikiGenes6908
SOURCE (Princeton)TBP
Genetics Home Reference (NIH)TBP
Genomic and cartography
GoldenPath hg38 (UCSC)TBP  -     chr6:170554333-170572870 +  6q27   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBP  -     6q27   [Description]    (hg19-Feb_2009)
EnsemblTBP - 6q27 [CytoView hg19]  TBP - 6q27 [CytoView hg38]
Mapping of homologs : NCBITBP [Mapview hg19]  TBP [Mapview hg38]
OMIM168600   600075   607136   
Gene and transcription
Genbank (Entrez)AK298272 AK304648 AK315222 BC109053 BC109054
RefSeq transcript (Entrez)NM_001172085 NM_003194
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TBP
Cluster EST : UnigeneHs.590872 [ NCBI ]
CGAP (NCI)Hs.590872
Alternative Splicing GalleryENSG00000112592
Gene ExpressionTBP [ NCBI-GEO ]   TBP [ EBI - ARRAY_EXPRESS ]   TBP [ SEEK ]   TBP [ MEM ]
Gene Expression Viewer (FireBrowse)TBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6908
GTEX Portal (Tissue expression)TBP
Human Protein AtlasENSG00000112592-TBP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20226   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20226  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20226
Splice isoforms : SwissVarP20226
PhosPhoSitePlusP20226
Domaine pattern : Prosite (Expaxy)TFIID (PS00351)   
Domains : Interpro (EBI)TBP    TBP_CS    TBP_dom_sf    TBP_eukaryotic   
Domain families : Pfam (Sanger)TBP (PF00352)   
Domain families : Pfam (NCBI)pfam00352   
Conserved Domain (NCBI)TBP
DMDM Disease mutations6908
Blocks (Seattle)TBP
PDB (SRS)1C9B    1CDW    1JFI    1NVP    1TGH    4ROC    4ROD    4ROE    5FUR    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD    5N9G   
PDB (PDBSum)1C9B    1CDW    1JFI    1NVP    1TGH    4ROC    4ROD    4ROE    5FUR    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD    5N9G   
PDB (IMB)1C9B    1CDW    1JFI    1NVP    1TGH    4ROC    4ROD    4ROE    5FUR    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD    5N9G   
PDB (RSDB)1C9B    1CDW    1JFI    1NVP    1TGH    4ROC    4ROD    4ROE    5FUR    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD    5N9G   
Structural Biology KnowledgeBase1C9B    1CDW    1JFI    1NVP    1TGH    4ROC    4ROD    4ROE    5FUR    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD    5N9G   
SCOP (Structural Classification of Proteins)1C9B    1CDW    1JFI    1NVP    1TGH    4ROC    4ROD    4ROE    5FUR    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD    5N9G   
CATH (Classification of proteins structures)1C9B    1CDW    1JFI    1NVP    1TGH    4ROC    4ROD    4ROE    5FUR    5IY6    5IY7    5IY8    5IY9    5IYA    5IYB    5IYC    5IYD    5N9G   
SuperfamilyP20226
Human Protein Atlas [tissue]ENSG00000112592-TBP [tissue]
Peptide AtlasP20226
HPRD02511
IPIIPI00022831   IPI00910049   IPI01025146   IPI00640595   IPI00956126   IPI00645617   IPI00641088   
Protein Interaction databases
DIP (DOE-UCLA)P20226
IntAct (EBI)P20226
FunCoupENSG00000112592
BioGRIDTBP
STRING (EMBL)TBP
ZODIACTBP
Ontologies - Pathways
QuickGOP20226
Ontology : AmiGOtranscription factor TFIIIB complex  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II core promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter sequence-specific DNA binding  RNA polymerase III general transcription initiation factor activity  RNA polymerase III regulatory region DNA binding  core promoter binding  TFIIB-class transcription factor binding  RNA polymerase II repressing transcription factor binding  female pronucleus  male pronucleus  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription factor complex  transcription factor TFIID complex  transcription factor TFIID complex  transcription factor TFIIA complex  nuclear euchromatin  cytoplasm  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase I promoter  termination of RNA polymerase I transcription  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription by RNA polymerase III  transcription by RNA polymerase III  spermatogenesis  transcription factor binding  transcription factor binding  viral process  RNA polymerase II general transcription initiation factor activity  aryl hydrocarbon receptor binding  enzyme binding  protein-containing complex  snRNA transcription by RNA polymerase II  transcription regulatory region DNA binding  positive regulation of gene expression, epigenetic  positive regulation of transcription, DNA-templated  RNA polymerase II preinitiation complex assembly  repressing transcription factor binding  RNA polymerase III preinitiation complex assembly  transcriptional preinitiation complex  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBItranscription factor TFIIIB complex  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II core promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter sequence-specific DNA binding  RNA polymerase III general transcription initiation factor activity  RNA polymerase III regulatory region DNA binding  core promoter binding  TFIIB-class transcription factor binding  RNA polymerase II repressing transcription factor binding  female pronucleus  male pronucleus  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription factor complex  transcription factor TFIID complex  transcription factor TFIID complex  transcription factor TFIIA complex  nuclear euchromatin  cytoplasm  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase I promoter  termination of RNA polymerase I transcription  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription by RNA polymerase III  transcription by RNA polymerase III  spermatogenesis  transcription factor binding  transcription factor binding  viral process  RNA polymerase II general transcription initiation factor activity  aryl hydrocarbon receptor binding  enzyme binding  protein-containing complex  snRNA transcription by RNA polymerase II  transcription regulatory region DNA binding  positive regulation of gene expression, epigenetic  positive regulation of transcription, DNA-templated  RNA polymerase II preinitiation complex assembly  repressing transcription factor binding  RNA polymerase III preinitiation complex assembly  transcriptional preinitiation complex  regulation of signal transduction by p53 class mediator  
Pathways : KEGGBasal transcription factors    Huntington's disease    HTLV-I infection    Herpes simplex infection    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx NetworkTBP
Atlas of Cancer Signalling NetworkTBP
Wikipedia pathwaysTBP
Orthology - Evolution
OrthoDB6908
GeneTree (enSembl)ENSG00000112592
Phylogenetic Trees/Animal Genes : TreeFamTBP
HOVERGENP20226
HOGENOMP20226
Homologs : HomoloGeneTBP
Homology/Alignments : Family Browser (UCSC)TBP
Gene fusions - Rearrangements
Fusion : QuiverTBP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBP
dbVarTBP
ClinVarTBP
1000_GenomesTBP 
Exome Variant ServerTBP
ExAC (Exome Aggregation Consortium)ENSG00000112592
GNOMAD BrowserENSG00000112592
Varsome BrowserTBP
Genetic variants : HAPMAP6908
Genomic Variants (DGV)TBP [DGVbeta]
DECIPHERTBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBP 
Mutations
ICGC Data PortalTBP 
TCGA Data PortalTBP 
Broad Tumor PortalTBP
OASIS PortalTBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TBP
DgiDB (Drug Gene Interaction Database)TBP
DoCM (Curated mutations)TBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TBP (select a term)
intoGenTBP
Cancer3DTBP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM168600    600075    607136   
Orphanet13776   
DisGeNETTBP
MedgenTBP
Genetic Testing Registry TBP
NextProtP20226 [Medical]
TSGene6908
GENETestsTBP
Target ValidationTBP
Huge Navigator TBP [HugePedia]
snp3D : Map Gene to Disease6908
BioCentury BCIQTBP
ClinGenTBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6908
Chemical/Pharm GKB GenePA36352
Clinical trialTBP
Miscellaneous
canSAR (ICR)TBP (select the gene name)
Probes
Litterature
PubMed364 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTBP
EVEXTBP
GoPubMedTBP
iHOPTBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:44:02 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.