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TBPL1 (TATA-box binding protein like 1)

Identity

Alias (NCBI)MGC:8389
MGC:9620
STUD
TLF
TLP
TRF2
HGNC (Hugo) TBPL1
HGNC Alias symbTLP
STUD
TRF2
TLF
HGNC Alias nameTBP-like factor
HGNC Previous nameTBP-like 1
LocusID (NCBI) 9519
Atlas_Id 55048
Location 6q23.2  [Link to chromosome band 6q23]
Location_base_pair Starts at 133953224 and ends at 133990430 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TBPL1 (6q23.2) / EDEM3 (1q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TBPL1   11589
Cards
Entrez_Gene (NCBI)TBPL1    TATA-box binding protein like 1
AliasesMGC:8389; MGC:9620; STUD; TLF; 
TLP; TRF2
GeneCards (Weizmann)TBPL1
Ensembl hg19 (Hinxton)ENSG00000028839 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000028839 [Gene_View]  ENSG00000028839 [Sequence]  chr6:133953224-133990430 [Contig_View]  TBPL1 [Vega]
ICGC DataPortalENSG00000028839
TCGA cBioPortalTBPL1
AceView (NCBI)TBPL1
Genatlas (Paris)TBPL1
SOURCE (Princeton)TBPL1
Genetics Home Reference (NIH)TBPL1
Genomic and cartography
GoldenPath hg38 (UCSC)TBPL1  -     chr6:133953224-133990430 +  6q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBPL1  -     6q23.2   [Description]    (hg19-Feb_2009)
GoldenPathTBPL1 - 6q23.2 [CytoView hg19]  TBPL1 - 6q23.2 [CytoView hg38]
ImmunoBaseENSG00000028839
Genome Data Viewer NCBITBPL1 [Mapview hg19]  
OMIM605521   
Gene and transcription
Genbank (Entrez)AB020881 AF130312 AF136570 AI187713 AK292320
RefSeq transcript (Entrez)NM_001253676 NM_004865
Consensus coding sequences : CCDS (NCBI)TBPL1
Gene ExpressionTBPL1 [ NCBI-GEO ]   TBPL1 [ EBI - ARRAY_EXPRESS ]   TBPL1 [ SEEK ]   TBPL1 [ MEM ]
Gene Expression Viewer (FireBrowse)TBPL1 [ Firebrowse - Broad ]
GenevisibleExpression of TBPL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9519
GTEX Portal (Tissue expression)TBPL1
Human Protein AtlasENSG00000028839-TBPL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62380   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62380  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62380
PhosPhoSitePlusP62380
Domains : Interpro (EBI)TBP    TBP-like    TBP_dom_sf   
Domain families : Pfam (Sanger)TBP (PF00352)   
Domain families : Pfam (NCBI)pfam00352   
Conserved Domain (NCBI)TBPL1
SuperfamilyP62380
AlphaFold pdb e-kbP62380   
Human Protein Atlas [tissue]ENSG00000028839-TBPL1 [tissue]
HPRD09272
Protein Interaction databases
DIP (DOE-UCLA)P62380
IntAct (EBI)P62380
BioGRIDTBPL1
STRING (EMBL)TBPL1
ZODIACTBPL1
Ontologies - Pathways
QuickGOP62380
Ontology : AmiGORNA polymerase II core promoter sequence-specific DNA binding  acrosome assembly  protein binding  transcription factor TFIIA complex  cytoplasm  dTTP biosynthetic process  DNA-templated transcription, initiation  transcription by RNA polymerase II  spermatid nucleus differentiation  RNA polymerase II general transcription initiation factor activity  general transcription initiation factor activity  
Ontology : EGO-EBIRNA polymerase II core promoter sequence-specific DNA binding  acrosome assembly  protein binding  transcription factor TFIIA complex  cytoplasm  dTTP biosynthetic process  DNA-templated transcription, initiation  transcription by RNA polymerase II  spermatid nucleus differentiation  RNA polymerase II general transcription initiation factor activity  general transcription initiation factor activity  
Pathways : KEGGBasal transcription factors    Huntington's disease    HTLV-I infection    Herpes simplex infection    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx NetworkTBPL1
Atlas of Cancer Signalling NetworkTBPL1
Wikipedia pathwaysTBPL1
Orthology - Evolution
OrthoDB9519
GeneTree (enSembl)ENSG00000028839
Phylogenetic Trees/Animal Genes : TreeFamTBPL1
Homologs : HomoloGeneTBPL1
Homology/Alignments : Family Browser (UCSC)TBPL1
Gene fusions - Rearrangements
Fusion : QuiverTBPL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBPL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBPL1
dbVarTBPL1
ClinVarTBPL1
MonarchTBPL1
1000_GenomesTBPL1 
Exome Variant ServerTBPL1
GNOMAD BrowserENSG00000028839
Varsome BrowserTBPL1
ACMGTBPL1 variants
VarityP62380
Genomic Variants (DGV)TBPL1 [DGVbeta]
DECIPHERTBPL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBPL1 
Mutations
ICGC Data PortalTBPL1 
TCGA Data PortalTBPL1 
Broad Tumor PortalTBPL1
OASIS PortalTBPL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBPL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTBPL1
Mutations and Diseases : HGMDTBPL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTBPL1
DgiDB (Drug Gene Interaction Database)TBPL1
DoCM (Curated mutations)TBPL1
CIViC (Clinical Interpretations of Variants in Cancer)TBPL1
Cancer3DTBPL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605521   
Orphanet
DisGeNETTBPL1
MedgenTBPL1
Genetic Testing Registry TBPL1
NextProtP62380 [Medical]
GENETestsTBPL1
Target ValidationTBPL1
Huge Navigator TBPL1 [HugePedia]
ClinGenTBPL1
Clinical trials, drugs, therapy
MyCancerGenomeTBPL1
Protein Interactions : CTDTBPL1
Pharm GKB GenePA36353
PharosP62380
Clinical trialTBPL1
Miscellaneous
canSAR (ICR)TBPL1
HarmonizomeTBPL1
DataMed IndexTBPL1
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTBPL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:29 CEST 2021

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