Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TBPL1 (TATA-box binding protein like 1)

Identity

Alias_namesTBP-like 1
Alias_symbol (synonym)TLP
STUD
TRF2
TLF
Other aliasMGC:8389
MGC:9620
HGNC (Hugo) TBPL1
LocusID (NCBI) 9519
Atlas_Id 55048
Location 6q23.2  [Link to chromosome band 6q23]
Location_base_pair Starts at 133953163 and ends at 133987500 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TBPL1 (6q23.2) / EDEM3 (1q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TBPL1   11589
Cards
Entrez_Gene (NCBI)TBPL1  9519  TATA-box binding protein like 1
AliasesMGC:8389; MGC:9620; STUD; TLF; 
TLP; TRF2
GeneCards (Weizmann)TBPL1
Ensembl hg19 (Hinxton)ENSG00000028839 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000028839 [Gene_View]  ENSG00000028839 [Sequence]  chr6:133953163-133987500 [Contig_View]  TBPL1 [Vega]
ICGC DataPortalENSG00000028839
TCGA cBioPortalTBPL1
AceView (NCBI)TBPL1
Genatlas (Paris)TBPL1
WikiGenes9519
SOURCE (Princeton)TBPL1
Genetics Home Reference (NIH)TBPL1
Genomic and cartography
GoldenPath hg38 (UCSC)TBPL1  -     chr6:133953163-133987500 +  6q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBPL1  -     6q23.2   [Description]    (hg19-Feb_2009)
EnsemblTBPL1 - 6q23.2 [CytoView hg19]  TBPL1 - 6q23.2 [CytoView hg38]
Mapping of homologs : NCBITBPL1 [Mapview hg19]  TBPL1 [Mapview hg38]
OMIM605521   
Gene and transcription
Genbank (Entrez)AB020881 AF130312 AF136570 AI187713 AK292320
RefSeq transcript (Entrez)NM_001253676 NM_004865
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TBPL1
Cluster EST : UnigeneHs.486507 [ NCBI ]
CGAP (NCI)Hs.486507
Alternative Splicing GalleryENSG00000028839
Gene ExpressionTBPL1 [ NCBI-GEO ]   TBPL1 [ EBI - ARRAY_EXPRESS ]   TBPL1 [ SEEK ]   TBPL1 [ MEM ]
Gene Expression Viewer (FireBrowse)TBPL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9519
GTEX Portal (Tissue expression)TBPL1
Human Protein AtlasENSG00000028839-TBPL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62380   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62380  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62380
Splice isoforms : SwissVarP62380
PhosPhoSitePlusP62380
Domains : Interpro (EBI)TBP    TBP-like    TBP_dom_sf   
Domain families : Pfam (Sanger)TBP (PF00352)   
Domain families : Pfam (NCBI)pfam00352   
Conserved Domain (NCBI)TBPL1
DMDM Disease mutations9519
Blocks (Seattle)TBPL1
SuperfamilyP62380
Human Protein Atlas [tissue]ENSG00000028839-TBPL1 [tissue]
Peptide AtlasP62380
HPRD09272
IPIIPI00032911   IPI00641561   IPI00641052   IPI00640447   IPI00644272   
Protein Interaction databases
DIP (DOE-UCLA)P62380
IntAct (EBI)P62380
FunCoupENSG00000028839
BioGRIDTBPL1
STRING (EMBL)TBPL1
ZODIACTBPL1
Ontologies - Pathways
QuickGOP62380
Ontology : AmiGOtranscription factor TFIIIB complex  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II core promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  RNA polymerase III regulatory region DNA binding  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  acrosome assembly  DNA-binding transcription factor activity  transcription coactivator activity  protein binding  transcription factor complex  transcription factor TFIID complex  transcription factor TFIIA complex  cytoplasm  dTTP biosynthetic process  transcription by RNA polymerase II  transcription by RNA polymerase II  spermatid nucleus differentiation  transcription factor binding  positive regulation of transcription by RNA polymerase II  RNA polymerase III preinitiation complex assembly  
Ontology : EGO-EBItranscription factor TFIIIB complex  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II core promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  RNA polymerase III regulatory region DNA binding  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  acrosome assembly  DNA-binding transcription factor activity  transcription coactivator activity  protein binding  transcription factor complex  transcription factor TFIID complex  transcription factor TFIIA complex  cytoplasm  dTTP biosynthetic process  transcription by RNA polymerase II  transcription by RNA polymerase II  spermatid nucleus differentiation  transcription factor binding  positive regulation of transcription by RNA polymerase II  RNA polymerase III preinitiation complex assembly  
Pathways : KEGGBasal transcription factors    Huntington's disease    HTLV-I infection    Herpes simplex infection    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx NetworkTBPL1
Atlas of Cancer Signalling NetworkTBPL1
Wikipedia pathwaysTBPL1
Orthology - Evolution
OrthoDB9519
GeneTree (enSembl)ENSG00000028839
Phylogenetic Trees/Animal Genes : TreeFamTBPL1
HOVERGENP62380
HOGENOMP62380
Homologs : HomoloGeneTBPL1
Homology/Alignments : Family Browser (UCSC)TBPL1
Gene fusions - Rearrangements
Fusion : QuiverTBPL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBPL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBPL1
dbVarTBPL1
ClinVarTBPL1
1000_GenomesTBPL1 
Exome Variant ServerTBPL1
ExAC (Exome Aggregation Consortium)ENSG00000028839
GNOMAD BrowserENSG00000028839
Varsome BrowserTBPL1
Genetic variants : HAPMAP9519
Genomic Variants (DGV)TBPL1 [DGVbeta]
DECIPHERTBPL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBPL1 
Mutations
ICGC Data PortalTBPL1 
TCGA Data PortalTBPL1 
Broad Tumor PortalTBPL1
OASIS PortalTBPL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBPL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTBPL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TBPL1
DgiDB (Drug Gene Interaction Database)TBPL1
DoCM (Curated mutations)TBPL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TBPL1 (select a term)
intoGenTBPL1
Cancer3DTBPL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605521   
Orphanet
DisGeNETTBPL1
MedgenTBPL1
Genetic Testing Registry TBPL1
NextProtP62380 [Medical]
TSGene9519
GENETestsTBPL1
Target ValidationTBPL1
Huge Navigator TBPL1 [HugePedia]
snp3D : Map Gene to Disease9519
BioCentury BCIQTBPL1
ClinGenTBPL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9519
Chemical/Pharm GKB GenePA36353
Clinical trialTBPL1
Miscellaneous
canSAR (ICR)TBPL1 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTBPL1
EVEXTBPL1
GoPubMedTBPL1
iHOPTBPL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:44:02 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.