Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TBX15 (T-box 15)

Identity

Alias_namesTBX14
T-box 14
Other alias
HGNC (Hugo) TBX15
LocusID (NCBI) 6913
Atlas_Id 54693
Location 1p12  [Link to chromosome band 1p12]
Location_base_pair Starts at 118883043 and ends at 118987853 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DDX20 (1p13.2) / TBX15 (1p12)HPS1 (10q24.2) / TBX15 (1p12)IGSF3 (1p13.1) / TBX15 (1p12)
DDX20 1p13.2 / TBX15 1p12IGSF3 1p13.1 / TBX15 1p12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TBX15   11594
Cards
Entrez_Gene (NCBI)TBX15  6913  T-box 15
AliasesTBX14
GeneCards (Weizmann)TBX15
Ensembl hg19 (Hinxton)ENSG00000092607 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092607 [Gene_View]  chr1:118883043-118987853 [Contig_View]  TBX15 [Vega]
ICGC DataPortalENSG00000092607
TCGA cBioPortalTBX15
AceView (NCBI)TBX15
Genatlas (Paris)TBX15
WikiGenes6913
SOURCE (Princeton)TBX15
Genetics Home Reference (NIH)TBX15
Genomic and cartography
GoldenPath hg38 (UCSC)TBX15  -     chr1:118883043-118987853 -  1p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBX15  -     1p12   [Description]    (hg19-Feb_2009)
EnsemblTBX15 - 1p12 [CytoView hg19]  TBX15 - 1p12 [CytoView hg38]
Mapping of homologs : NCBITBX15 [Mapview hg19]  TBX15 [Mapview hg38]
OMIM260660   604127   
Gene and transcription
Genbank (Entrez)AK096396 AK127536 BC122553 BX537778 CA412451
RefSeq transcript (Entrez)NM_001330677 NM_152380
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TBX15
Cluster EST : UnigeneHs.146196 [ NCBI ]
CGAP (NCI)Hs.146196
Alternative Splicing GalleryENSG00000092607
Gene ExpressionTBX15 [ NCBI-GEO ]   TBX15 [ EBI - ARRAY_EXPRESS ]   TBX15 [ SEEK ]   TBX15 [ MEM ]
Gene Expression Viewer (FireBrowse)TBX15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6913
GTEX Portal (Tissue expression)TBX15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96SF7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96SF7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96SF7
Splice isoforms : SwissVarQ96SF7
PhosPhoSitePlusQ96SF7
Domaine pattern : Prosite (Expaxy)TBOX_1 (PS01283)    TBOX_2 (PS01264)    TBOX_3 (PS50252)   
Domains : Interpro (EBI)p53-like_TF_DNA-bd    TF_T-box    TF_T-box_CS   
Domain families : Pfam (Sanger)T-box (PF00907)   
Domain families : Pfam (NCBI)pfam00907   
Domain families : Smart (EMBL)TBOX (SM00425)  
Conserved Domain (NCBI)TBX15
DMDM Disease mutations6913
Blocks (Seattle)TBX15
SuperfamilyQ96SF7
Human Protein AtlasENSG00000092607
Peptide AtlasQ96SF7
HPRD16035
IPIIPI00163361   IPI00643004   IPI00844280   IPI00874142   
Protein Interaction databases
DIP (DOE-UCLA)Q96SF7
IntAct (EBI)Q96SF7
FunCoupENSG00000092607
BioGRIDTBX15
STRING (EMBL)TBX15
ZODIACTBX15
Ontologies - Pathways
QuickGOQ96SF7
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  RNA polymerase II transcription corepressor activity  protein binding  transcription, DNA-templated  protein homodimerization activity  protein heterodimerization activity  embryonic cranial skeleton morphogenesis  Tle3-Aes complex  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  RNA polymerase II transcription corepressor activity  protein binding  transcription, DNA-templated  protein homodimerization activity  protein heterodimerization activity  embryonic cranial skeleton morphogenesis  Tle3-Aes complex  
NDEx NetworkTBX15
Atlas of Cancer Signalling NetworkTBX15
Wikipedia pathwaysTBX15
Orthology - Evolution
OrthoDB6913
GeneTree (enSembl)ENSG00000092607
Phylogenetic Trees/Animal Genes : TreeFamTBX15
HOVERGENQ96SF7
HOGENOMQ96SF7
Homologs : HomoloGeneTBX15
Homology/Alignments : Family Browser (UCSC)TBX15
Gene fusions - Rearrangements
Fusion : MitelmanDDX20/TBX15 [1p13.2/1p12]  [t(1;1)(p12;p13)]  
Fusion : MitelmanIGSF3/TBX15 [1p13.1/1p12]  [t(1;1)(p12;p13)]  
Fusion: TCGADDX20 1p13.2 TBX15 1p12 LAML
Fusion: TCGAIGSF3 1p13.1 TBX15 1p12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBX15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBX15
dbVarTBX15
ClinVarTBX15
1000_GenomesTBX15 
Exome Variant ServerTBX15
ExAC (Exome Aggregation Consortium)TBX15 (select the gene name)
Genetic variants : HAPMAP6913
Genomic Variants (DGV)TBX15 [DGVbeta]
DECIPHERTBX15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBX15 
Mutations
ICGC Data PortalTBX15 
TCGA Data PortalTBX15 
Broad Tumor PortalTBX15
OASIS PortalTBX15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBX15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTBX15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TBX15
DgiDB (Drug Gene Interaction Database)TBX15
DoCM (Curated mutations)TBX15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TBX15 (select a term)
intoGenTBX15
Cancer3DTBX15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM260660    604127   
Orphanet12268   
MedgenTBX15
Genetic Testing Registry TBX15
NextProtQ96SF7 [Medical]
TSGene6913
GENETestsTBX15
Huge Navigator TBX15 [HugePedia]
snp3D : Map Gene to Disease6913
BioCentury BCIQTBX15
ClinGenTBX15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6913
Chemical/Pharm GKB GenePA36357
Clinical trialTBX15
Miscellaneous
canSAR (ICR)TBX15 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTBX15
EVEXTBX15
GoPubMedTBX15
iHOPTBX15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:40:27 CEST 2017

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