| Nomenclature |
HGNC (Hugo) | TBX21 11599 |
| Cards |
Entrez_Gene (NCBI) | TBX21 T-box transcription factor 21 |
Aliases | T-PET; T-bet; TBET; TBLYM |
GeneCards (Weizmann) | TBX21 |
Ensembl hg19 (Hinxton) | ENSG00000073861 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000073861 [Gene_View]  ENSG00000073861 [Sequence] chr17:47733236-47746122 [Contig_View] TBX21 [Vega] |
ICGC DataPortal | ENSG00000073861 |
TCGA cBioPortal | TBX21 |
AceView (NCBI) | TBX21 |
Genatlas (Paris) | TBX21 |
SOURCE (Princeton) | TBX21 |
Genetics Home Reference (NIH) | TBX21 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | TBX21 - chr17:47733236-47746122 + 17q21.32 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | TBX21 - 17q21.32 [Description] (hg19-Feb_2009) |
GoldenPath | TBX21 - 17q21.32 [CytoView hg19] TBX21 - 17q21.32 [CytoView hg38] |
ImmunoBase | ENSG00000073861 |
genome Data Viewer NCBI | TBX21 [Mapview hg19] |
OMIM | 208550 604895 |
| Gene and transcription |
Genbank (Entrez) | AF093098 AF241243 AK223634 BC039739 |
RefSeq transcript (Entrez) | NM_013351 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | TBX21 |
Alternative Splicing Gallery | ENSG00000073861 |
Gene Expression | TBX21 [ NCBI-GEO ] TBX21 [ EBI - ARRAY_EXPRESS ]
TBX21 [ SEEK ] TBX21 [ MEM ] |
Gene Expression Viewer (FireBrowse) | TBX21 [ Firebrowse - Broad ] |
Genevisible | Expression of TBX21 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 30009 |
GTEX Portal (Tissue expression) | TBX21 |
Human Protein Atlas | ENSG00000073861-TBX21 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q9UL17 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q9UL17 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q9UL17 |
Splice isoforms : SwissVar | Q9UL17 |
PhosPhoSitePlus | Q9UL17 |
Domaine pattern : Prosite (Expaxy) | TBOX_1 (PS01283) TBOX_2 (PS01264) TBOX_3 (PS50252) |
Domains : Interpro (EBI) | p53-like_TF_DNA-bd T-box_sf TF_T-box TF_T-box_CS |
Domain families : Pfam (Sanger) | T-box (PF00907) |
Domain families : Pfam (NCBI) | pfam00907 |
Domain families : Smart (EMBL) | TBOX (SM00425) |
Conserved Domain (NCBI) | TBX21 |
Blocks (Seattle) | TBX21 |
Superfamily | Q9UL17 |
Human Protein Atlas [tissue] | ENSG00000073861-TBX21 [tissue] |
Peptide Atlas | Q9UL17 |
HPRD | 05355 |
IPI | IPI00007732 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q9UL17 |
IntAct (EBI) | Q9UL17 |
BioGRID | TBX21 |
STRING (EMBL) | TBX21 |
ZODIAC | TBX21 |
| Ontologies - Pathways |
QuickGO | Q9UL17 |
Ontology : AmiGO | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II activating transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cell fate specification heart looping DNA-binding transcription factor activity protein binding nucleus nucleus regulation of transcription, DNA-templated multicellular organism development response to virus T cell differentiation negative regulation of interleukin-2 production neuronal cell body proteasome-mediated ubiquitin-dependent protein catabolic process sequence-specific DNA binding regulation of T cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of isotype switching to IgG isotypes cellular response to organic substance lymphocyte migration lymphocyte migration negative regulation of T-helper 17 cell differentiation negative regulation of T-helper 17 cell lineage commitment negative regulation of T-helper 2 cell cytokine production |
Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II activating transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cell fate specification heart looping DNA-binding transcription factor activity protein binding nucleus nucleus regulation of transcription, DNA-templated multicellular organism development response to virus T cell differentiation negative regulation of interleukin-2 production neuronal cell body proteasome-mediated ubiquitin-dependent protein catabolic process sequence-specific DNA binding regulation of T cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of isotype switching to IgG isotypes cellular response to organic substance lymphocyte migration lymphocyte migration negative regulation of T-helper 17 cell differentiation negative regulation of T-helper 17 cell lineage commitment negative regulation of T-helper 2 cell cytokine production |
Pathways : KEGG | Inflammatory bowel disease (IBD) |
NDEx Network | TBX21 |
Atlas of Cancer Signalling Network | TBX21 |
Wikipedia pathways | TBX21 |
| Orthology - Evolution |
OrthoDB | 30009 |
GeneTree (enSembl) | ENSG00000073861 |
Phylogenetic Trees/Animal Genes : TreeFam | TBX21 |
HOGENOM | Q9UL17 |
Homologs : HomoloGene | TBX21 |
Homology/Alignments : Family Browser (UCSC) | TBX21 |
| Gene fusions - Rearrangements |
Fusion : Quiver | TBX21 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | TBX21 [hg38] |
dbVar | TBX21 |
ClinVar | TBX21 |
Monarch | TBX21 |
1000_Genomes | TBX21 |
Exome Variant Server | TBX21 |
GNOMAD Browser | ENSG00000073861 |
Varsome Browser | TBX21 |
Genomic Variants (DGV) | TBX21 [DGVbeta] |
DECIPHER | TBX21 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | TBX21 |
| Mutations |
ICGC Data Portal | TBX21 |
TCGA Data Portal | TBX21 |
Broad Tumor Portal | TBX21 |
OASIS Portal | TBX21 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | TBX21 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | TBX21 |
Mutations and Diseases : HGMD | TBX21 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search TBX21 |
DgiDB (Drug Gene Interaction Database) | TBX21 |
DoCM (Curated mutations) | TBX21 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | TBX21 (select a term) |
intoGen | TBX21 |
Cancer3D | TBX21(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
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OMIM | 208550 604895 |
Orphanet | |
DisGeNET | TBX21 |
Medgen | TBX21 |
Genetic Testing Registry | TBX21
|
NextProt | Q9UL17 [Medical] |
GENETests | TBX21 |
Target Validation | TBX21 |
Huge Navigator |
TBX21 [HugePedia] |
ClinGen | TBX21 |
| Clinical trials, drugs, therapy |
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MyCancerGenome | TBX21 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA36362 |
Pharos | Q9UL17 |
Clinical trial | TBX21 |
| Miscellaneous |
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canSAR (ICR) | TBX21 (select the gene name) |
Harmonizome | TBX21 |
DataMed Index | TBX21 |
| Probes |
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| Litterature |
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PubMed | 205 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | TBX21 |