| Nomenclature |
|---|
| HGNC (Hugo) | TBX21 11599 |
| Cards |
|---|
| Entrez_Gene (NCBI) | TBX21 30009 T-box 21 |
| Aliases | T-PET; T-bet; TBET; TBLYM |
| GeneCards (Weizmann) | TBX21 |
| Ensembl hg19 (Hinxton) | ENSG00000073861 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000073861 [Gene_View] chr17:47733244-47746119 [Contig_View] TBX21 [Vega] |
| ICGC DataPortal | ENSG00000073861 |
| TCGA cBioPortal | TBX21 |
| AceView (NCBI) | TBX21 |
| Genatlas (Paris) | TBX21 |
| WikiGenes | 30009 |
| SOURCE (Princeton) | TBX21 |
| Genetics Home Reference (NIH) | TBX21 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | TBX21 - chr17:47733244-47746119 + 17q21.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | TBX21 - 17q21.32 [Description] (hg19-Feb_2009) |
| Ensembl | TBX21 - 17q21.32 [CytoView hg19] TBX21 - 17q21.32 [CytoView hg38] |
| Mapping of homologs : NCBI | TBX21 [Mapview hg19] TBX21 [Mapview hg38] |
| OMIM | 208550 604895 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF093098 AF241243 AK223634 BC039739 |
| RefSeq transcript (Entrez) | NM_013351 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | TBX21 |
| Cluster EST : Unigene | Hs.272409 [ NCBI ] |
| CGAP (NCI) | Hs.272409 |
| Alternative Splicing Gallery | ENSG00000073861 |
| Gene Expression | TBX21 [ NCBI-GEO ] TBX21 [ EBI - ARRAY_EXPRESS ]
TBX21 [ SEEK ] TBX21 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | TBX21 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 30009 |
| GTEX Portal (Tissue expression) | TBX21 |
| Human Protein Atlas | ENSG00000073861-TBX21 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q9UL17 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q9UL17 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q9UL17 |
| Splice isoforms : SwissVar | Q9UL17 |
| PhosPhoSitePlus | Q9UL17 |
| Domaine pattern : Prosite (Expaxy) | TBOX_1 (PS01283) TBOX_2 (PS01264) TBOX_3 (PS50252) |
| Domains : Interpro (EBI) | p53-like_TF_DNA-bd TF_T-box TF_T-box_CS |
| Domain families : Pfam (Sanger) | T-box (PF00907) |
| Domain families : Pfam (NCBI) | pfam00907 |
| Domain families : Smart (EMBL) | TBOX (SM00425) |
| Conserved Domain (NCBI) | TBX21 |
| DMDM Disease mutations | 30009 |
| Blocks (Seattle) | TBX21 |
| Superfamily | Q9UL17 |
| Human Protein Atlas [tissue] | ENSG00000073861-TBX21 [tissue] |
| Peptide Atlas | Q9UL17 |
| HPRD | 05355 |
| IPI | IPI00007732 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q9UL17 |
| IntAct (EBI) | Q9UL17 |
| FunCoup | ENSG00000073861 |
| BioGRID | TBX21 |
| STRING (EMBL) | TBX21 |
| ZODIAC | TBX21 |
| Ontologies - Pathways |
|---|
| QuickGO | Q9UL17 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA binding transcription factor activity protein binding nucleus transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development response to virus T cell differentiation negative regulation of interleukin-2 production neuronal cell body proteasome-mediated ubiquitin-dependent protein catabolic process sequence-specific DNA binding transcription regulatory region DNA binding regulation of T cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of isotype switching to IgG isotypes cellular response to organic substance lymphocyte migration negative regulation of T-helper 17 cell differentiation negative regulation of T-helper 17 cell lineage commitment negative regulation of T-helper 2 cell cytokine production |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA binding transcription factor activity protein binding nucleus transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development response to virus T cell differentiation negative regulation of interleukin-2 production neuronal cell body proteasome-mediated ubiquitin-dependent protein catabolic process sequence-specific DNA binding transcription regulatory region DNA binding regulation of T cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of isotype switching to IgG isotypes cellular response to organic substance lymphocyte migration negative regulation of T-helper 17 cell differentiation negative regulation of T-helper 17 cell lineage commitment negative regulation of T-helper 2 cell cytokine production |
| NDEx Network | TBX21 |
| Atlas of Cancer Signalling Network | TBX21 |
| Wikipedia pathways | TBX21 |
| Orthology - Evolution |
|---|
| OrthoDB | 30009 |
| GeneTree (enSembl) | ENSG00000073861 |
| Phylogenetic Trees/Animal Genes : TreeFam | TBX21 |
| HOVERGEN | Q9UL17 |
| HOGENOM | Q9UL17 |
| Homologs : HomoloGene | TBX21 |
| Homology/Alignments : Family Browser (UCSC) | TBX21 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | TBX21 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | TBX21 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | TBX21 |
| dbVar | TBX21 |
| ClinVar | TBX21 |
| 1000_Genomes | TBX21 |
| Exome Variant Server | TBX21 |
| ExAC (Exome Aggregation Consortium) | ENSG00000073861 |
| GNOMAD Browser | ENSG00000073861 |
| Genetic variants : HAPMAP | 30009 |
| Genomic Variants (DGV) | TBX21 [DGVbeta] |
| DECIPHER | TBX21 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | TBX21 |
| Mutations |
|---|
| ICGC Data Portal | TBX21 |
| TCGA Data Portal | TBX21 |
| Broad Tumor Portal | TBX21 |
| OASIS Portal | TBX21 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | TBX21 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | TBX21 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search TBX21 |
| DgiDB (Drug Gene Interaction Database) | TBX21 |
| DoCM (Curated mutations) | TBX21 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | TBX21 (select a term) |
| intoGen | TBX21 |
| Cancer3D | TBX21(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 208550 604895 |
| Orphanet | |
| DisGeNET | TBX21 |
| Medgen | TBX21 |
| Genetic Testing Registry | TBX21
|
| NextProt | Q9UL17 [Medical] |
| TSGene | 30009 |
| GENETests | TBX21 |
| Target Validation | TBX21 |
| Huge Navigator |
TBX21 [HugePedia] |
| snp3D : Map Gene to Disease | 30009 |
| BioCentury BCIQ | TBX21 |
| ClinGen | TBX21 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 30009 |
| Chemical/Pharm GKB Gene | PA36362 |
| Clinical trial | TBX21 |
| Miscellaneous |
|---|
| canSAR (ICR) | TBX21 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 184 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | TBX21 |
| EVEX | TBX21 |
| GoPubMed | TBX21 |
| iHOP | TBX21 |
