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TC2N (tandem C2 domains, nuclear)

Identity

Alias_namesC14orf47
MTAC2D1
chromosome 14 open reading frame 47
membrane targeting (tandem) C2 domain containing 1
Alias_symbol (synonym)FLJ36557
Tac2-N
C2CD1
Other alias
HGNC (Hugo) TC2N
LocusID (NCBI) 123036
Atlas_Id 56170
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 91779752 and ends at 91836526 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CATSPERB (14q32.12) / TC2N (14q32.12)TC2N (14q32.12) / FBLN5 (14q32.12)TC2N (14q32.12) / LPP (3q28)
TC2N (14q32.12) / TRIP11 (14q32.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TC2N   19859
Cards
Entrez_Gene (NCBI)TC2N  123036  tandem C2 domains, nuclear
AliasesC14orf47; C2CD1; MTAC2D1; Tac2-N
GeneCards (Weizmann)TC2N
Ensembl hg19 (Hinxton)ENSG00000165929 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165929 [Gene_View]  chr14:91779752-91836526 [Contig_View]  TC2N [Vega]
ICGC DataPortalENSG00000165929
TCGA cBioPortalTC2N
AceView (NCBI)TC2N
Genatlas (Paris)TC2N
WikiGenes123036
SOURCE (Princeton)TC2N
Genetics Home Reference (NIH)TC2N
Genomic and cartography
GoldenPath hg38 (UCSC)TC2N  -     chr14:91779752-91836526 -  14q32.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TC2N  -     14q32.12   [Description]    (hg19-Feb_2009)
EnsemblTC2N - 14q32.12 [CytoView hg19]  TC2N - 14q32.12 [CytoView hg38]
Mapping of homologs : NCBITC2N [Mapview hg19]  TC2N [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK093876 AK126359 AM392691 AM393059 AW275132
RefSeq transcript (Entrez)NM_001128595 NM_001128596 NM_001289134 NM_152332
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_187598
Consensus coding sequences : CCDS (NCBI)TC2N
Cluster EST : UnigeneHs.510262 [ NCBI ]
CGAP (NCI)Hs.510262
Alternative Splicing GalleryENSG00000165929
Gene ExpressionTC2N [ NCBI-GEO ]   TC2N [ EBI - ARRAY_EXPRESS ]   TC2N [ SEEK ]   TC2N [ MEM ]
Gene Expression Viewer (FireBrowse)TC2N [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)123036
GTEX Portal (Tissue expression)TC2N
Human Protein AtlasENSG00000165929-TC2N [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N9U0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N9U0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N9U0
Splice isoforms : SwissVarQ8N9U0
PhosPhoSitePlusQ8N9U0
Domaine pattern : Prosite (Expaxy)C2 (PS50004)   
Domains : Interpro (EBI)C2_dom    Tac2-N   
Domain families : Pfam (Sanger)C2 (PF00168)   
Domain families : Pfam (NCBI)pfam00168   
Domain families : Smart (EMBL)C2 (SM00239)  
Conserved Domain (NCBI)TC2N
DMDM Disease mutations123036
Blocks (Seattle)TC2N
SuperfamilyQ8N9U0
Human Protein Atlas [tissue]ENSG00000165929-TC2N [tissue]
Peptide AtlasQ8N9U0
HPRD11375
IPIIPI00167811   IPI00376945   IPI01025211   
Protein Interaction databases
DIP (DOE-UCLA)Q8N9U0
IntAct (EBI)Q8N9U0
FunCoupENSG00000165929
BioGRIDTC2N
STRING (EMBL)TC2N
ZODIACTC2N
Ontologies - Pathways
QuickGOQ8N9U0
Ontology : AmiGOmolecular_function  calcium ion binding  calcium-dependent phospholipid binding  cellular_component  nucleus  plasma membrane  vesicle fusion  regulation of gene expression  regulation of calcium ion-dependent exocytosis  syntaxin binding  regulation of blood coagulation  clathrin binding  calcium ion-regulated exocytosis of neurotransmitter  presynapse  
Ontology : EGO-EBImolecular_function  calcium ion binding  calcium-dependent phospholipid binding  cellular_component  nucleus  plasma membrane  vesicle fusion  regulation of gene expression  regulation of calcium ion-dependent exocytosis  syntaxin binding  regulation of blood coagulation  clathrin binding  calcium ion-regulated exocytosis of neurotransmitter  presynapse  
NDEx NetworkTC2N
Atlas of Cancer Signalling NetworkTC2N
Wikipedia pathwaysTC2N
Orthology - Evolution
OrthoDB123036
GeneTree (enSembl)ENSG00000165929
Phylogenetic Trees/Animal Genes : TreeFamTC2N
HOVERGENQ8N9U0
HOGENOMQ8N9U0
Homologs : HomoloGeneTC2N
Homology/Alignments : Family Browser (UCSC)TC2N
Gene fusions - Rearrangements
Tumor Fusion PortalTC2N
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTC2N [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TC2N
dbVarTC2N
ClinVarTC2N
1000_GenomesTC2N 
Exome Variant ServerTC2N
ExAC (Exome Aggregation Consortium)ENSG00000165929
GNOMAD BrowserENSG00000165929
Genetic variants : HAPMAP123036
Genomic Variants (DGV)TC2N [DGVbeta]
DECIPHERTC2N [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTC2N 
Mutations
ICGC Data PortalTC2N 
TCGA Data PortalTC2N 
Broad Tumor PortalTC2N
OASIS PortalTC2N [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTC2N  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTC2N
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TC2N
DgiDB (Drug Gene Interaction Database)TC2N
DoCM (Curated mutations)TC2N (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TC2N (select a term)
intoGenTC2N
Cancer3DTC2N(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTC2N
MedgenTC2N
Genetic Testing Registry TC2N
NextProtQ8N9U0 [Medical]
TSGene123036
GENETestsTC2N
Target ValidationTC2N
Huge Navigator TC2N [HugePedia]
snp3D : Map Gene to Disease123036
BioCentury BCIQTC2N
ClinGenTC2N
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD123036
Chemical/Pharm GKB GenePA162405395
Clinical trialTC2N
Miscellaneous
canSAR (ICR)TC2N (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTC2N
EVEXTC2N
GoPubMedTC2N
iHOPTC2N
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:37:55 CET 2017

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