Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TCEA1 (transcription elongation factor A1)

Identity

Alias_namesTCEA
GTF2S
transcription elongation factor A (SII)
Alias_symbol (synonym)SII
TF2S
TFIIS
Other alias
HGNC (Hugo) TCEA1
LocusID (NCBI) 6917
Atlas_Id 409
Location 8q11.23  [Link to chromosome band 8q11]
Location_base_pair Starts at 54879114 and ends at 54935016 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PLAG1 (8q12.1) / TCEA1 (8q11.23)TCEA1 (8q11.23) / PLAG1 (8q12.1)TCEA1 8q11.23 / PLAG1 8q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Head and Neck: Pleomorphic salivary gland adenoma with ins(8)(q12;q11q11) TCEA1/PLAG1
Head and Neck: Salivary gland tumors: an overview


External links

Nomenclature
HGNC (Hugo)TCEA1   11612
Cards
Entrez_Gene (NCBI)TCEA1  6917  transcription elongation factor A1
AliasesGTF2S; SII; TCEA; TF2S; 
TFIIS
GeneCards (Weizmann)TCEA1
Ensembl hg19 (Hinxton)ENSG00000187735 [Gene_View]  chr8:54879114-54935016 [Contig_View]  TCEA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000187735 [Gene_View]  chr8:54879114-54935016 [Contig_View]  TCEA1 [Vega]
ICGC DataPortalENSG00000187735
TCGA cBioPortalTCEA1
AceView (NCBI)TCEA1
Genatlas (Paris)TCEA1
WikiGenes6917
SOURCE (Princeton)TCEA1
Genetics Home Reference (NIH)TCEA1
Genomic and cartography
GoldenPath hg19 (UCSC)TCEA1  -     chr8:54879114-54935016 -  8q11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TCEA1  -     8q11.23   [Description]    (hg38-Dec_2013)
EnsemblTCEA1 - 8q11.23 [CytoView hg19]  TCEA1 - 8q11.23 [CytoView hg38]
Mapping of homologs : NCBITCEA1 [Mapview hg19]  TCEA1 [Mapview hg38]
OMIM601425   
Gene and transcription
Genbank (Entrez)AK026617 AK094425 AK290454 AK297729 AK297957
RefSeq transcript (Entrez)NM_006756 NM_201437
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008183 NW_004929339
Consensus coding sequences : CCDS (NCBI)TCEA1
Cluster EST : UnigeneHs.491745 [ NCBI ]
CGAP (NCI)Hs.491745
Alternative Splicing GalleryENSG00000187735
Gene ExpressionTCEA1 [ NCBI-GEO ]   TCEA1 [ EBI - ARRAY_EXPRESS ]   TCEA1 [ SEEK ]   TCEA1 [ MEM ]
Gene Expression Viewer (FireBrowse)TCEA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6917
GTEX Portal (Tissue expression)TCEA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23193   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23193  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23193
Splice isoforms : SwissVarP23193
PhosPhoSitePlusP23193
Domaine pattern : Prosite (Expaxy)TFIIS_CENTRAL (PS51321)    TFIIS_N (PS51319)    ZF_TFIIS_1 (PS00466)    ZF_TFIIS_2 (PS51133)   
Domains : Interpro (EBI)TF_IIS-rel    TFIIS/CRSP70_N_sub    TFIIS_cen_dom    TFIIS_N    TFS2M    TFSII    Znf_TFIIS   
Domain families : Pfam (Sanger)Med26 (PF08711)    TFIIS_C (PF01096)    TFIIS_M (PF07500)   
Domain families : Pfam (NCBI)pfam08711    pfam01096    pfam07500   
Domain families : Smart (EMBL)TFS2M (SM00510)  TFS2N (SM00509)  ZnF_C2C2 (SM00440)  
Conserved Domain (NCBI)TCEA1
DMDM Disease mutations6917
Blocks (Seattle)TCEA1
PDB (SRS)1TFI    3NDQ   
PDB (PDBSum)1TFI    3NDQ   
PDB (IMB)1TFI    3NDQ   
PDB (RSDB)1TFI    3NDQ   
Structural Biology KnowledgeBase1TFI    3NDQ   
SCOP (Structural Classification of Proteins)1TFI    3NDQ   
CATH (Classification of proteins structures)1TFI    3NDQ   
SuperfamilyP23193
Human Protein AtlasENSG00000187735
Peptide AtlasP23193
HPRD03252
IPIIPI00333215   IPI00218106   IPI00922871   IPI00975678   IPI00974100   IPI00974396   IPI00979974   
Protein Interaction databases
DIP (DOE-UCLA)P23193
IntAct (EBI)P23193
FunCoupENSG00000187735
BioGRIDTCEA1
STRING (EMBL)TCEA1
ZODIACTCEA1
Ontologies - Pathways
QuickGOP23193
Ontology : AmiGODNA binding  protein binding  nucleus  nucleoplasm  nucleolus  transcription-coupled nucleotide-excision repair  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  zinc ion binding  regulation of DNA-templated transcription, elongation  positive regulation of exoribonuclease activity  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  nucleoplasm  nucleolus  transcription-coupled nucleotide-excision repair  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  zinc ion binding  regulation of DNA-templated transcription, elongation  positive regulation of exoribonuclease activity  
NDEx NetworkTCEA1
Atlas of Cancer Signalling NetworkTCEA1
Wikipedia pathwaysTCEA1
Orthology - Evolution
OrthoDB6917
GeneTree (enSembl)ENSG00000187735
Phylogenetic Trees/Animal Genes : TreeFamTCEA1
HOVERGENP23193
HOGENOMP23193
Homologs : HomoloGeneTCEA1
Homology/Alignments : Family Browser (UCSC)TCEA1
Gene fusions - Rearrangements
Fusion : MitelmanTCEA1/PLAG1 [8q11.23/8q12.1]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCEA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCEA1
dbVarTCEA1
ClinVarTCEA1
1000_GenomesTCEA1 
Exome Variant ServerTCEA1
ExAC (Exome Aggregation Consortium)TCEA1 (select the gene name)
Genetic variants : HAPMAP6917
Genomic Variants (DGV)TCEA1 [DGVbeta]
DECIPHER (Syndromes)8:54879114-54935016  ENSG00000187735
CONAN: Copy Number AnalysisTCEA1 
Mutations
ICGC Data PortalTCEA1 
TCGA Data PortalTCEA1 
Broad Tumor PortalTCEA1
OASIS PortalTCEA1 [ Somatic mutations - Copy number]
Cancer Gene: CensusTCEA1 
Somatic Mutations in Cancer : COSMICTCEA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTCEA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TCEA1
DgiDB (Drug Gene Interaction Database)TCEA1
DoCM (Curated mutations)TCEA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TCEA1 (select a term)
intoGenTCEA1
Cancer3DTCEA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601425   
Orphanet
MedgenTCEA1
Genetic Testing Registry TCEA1
NextProtP23193 [Medical]
TSGene6917
GENETestsTCEA1
Huge Navigator TCEA1 [HugePedia]
snp3D : Map Gene to Disease6917
BioCentury BCIQTCEA1
ClinGenTCEA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6917
Chemical/Pharm GKB GenePA36371
Clinical trialTCEA1
Miscellaneous
canSAR (ICR)TCEA1 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTCEA1
EVEXTCEA1
GoPubMedTCEA1
iHOPTCEA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:22:00 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.