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TCEA2 (transcription elongation factor A2)

Identity

Alias (NCBI)TFIIS
HGNC (Hugo) TCEA2
HGNC Alias symbTFIIS
HGNC Previous nametranscription elongation factor A (SII), 2
LocusID (NCBI) 6919
Atlas_Id 74562
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 64056972 and ends at 64072347 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TCEA2   11614
Cards
Entrez_Gene (NCBI)TCEA2    transcription elongation factor A2
AliasesTFIIS
GeneCards (Weizmann)TCEA2
Ensembl hg19 (Hinxton)ENSG00000171703 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171703 [Gene_View]  ENSG00000171703 [Sequence]  chr20:64056972-64072347 [Contig_View]  TCEA2 [Vega]
ICGC DataPortalENSG00000171703
TCGA cBioPortalTCEA2
AceView (NCBI)TCEA2
Genatlas (Paris)TCEA2
SOURCE (Princeton)TCEA2
Genetics Home Reference (NIH)TCEA2
Genomic and cartography
GoldenPath hg38 (UCSC)TCEA2  -     chr20:64056972-64072347 +  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCEA2  -     20q13.33   [Description]    (hg19-Feb_2009)
GoldenPathTCEA2 - 20q13.33 [CytoView hg19]  TCEA2 - 20q13.33 [CytoView hg38]
ImmunoBaseENSG00000171703
Genome Data Viewer NCBITCEA2 [Mapview hg19]  
OMIM604784   
Gene and transcription
Genbank (Entrez)AJ844626 AJ844627 AK027824 AK226140 AW474513
RefSeq transcript (Entrez)NM_003195 NM_198723
Consensus coding sequences : CCDS (NCBI)TCEA2
Gene ExpressionTCEA2 [ NCBI-GEO ]   TCEA2 [ EBI - ARRAY_EXPRESS ]   TCEA2 [ SEEK ]   TCEA2 [ MEM ]
Gene Expression Viewer (FireBrowse)TCEA2 [ Firebrowse - Broad ]
GenevisibleExpression of TCEA2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6919
GTEX Portal (Tissue expression)TCEA2
Human Protein AtlasENSG00000171703-TCEA2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15560   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15560  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15560
PhosPhoSitePlusQ15560
Domaine pattern : Prosite (Expaxy)TFIIS_CENTRAL (PS51321)    TFIIS_N (PS51319)    ZF_TFIIS_1 (PS00466)    ZF_TFIIS_2 (PS51133)   
Domains : Interpro (EBI)TF_IIS-typ    TFIIS/CRSP70_N_sub    TFIIS/LEDGF_dom_sf    TFIIS_cen_dom    TFIIS_cen_dom_sf    TFIIS_N    TFSII    Znf_TFIIS   
Domain families : Pfam (Sanger)Med26 (PF08711)    TFIIS_C (PF01096)    TFIIS_M (PF07500)   
Domain families : Pfam (NCBI)pfam08711    pfam01096    pfam07500   
Domain families : Smart (EMBL)TFS2M (SM00510)  TFS2N (SM00509)  ZnF_C2C2 (SM00440)  
Conserved Domain (NCBI)TCEA2
PDB (RSDB)2LW4   
PDB Europe2LW4   
PDB (PDBSum)2LW4   
PDB (IMB)2LW4   
Structural Biology KnowledgeBase2LW4   
SCOP (Structural Classification of Proteins)2LW4   
CATH (Classification of proteins structures)2LW4   
SuperfamilyQ15560
AlphaFold pdb e-kbQ15560   
Human Protein Atlas [tissue]ENSG00000171703-TCEA2 [tissue]
HPRD16069
Protein Interaction databases
DIP (DOE-UCLA)Q15560
IntAct (EBI)Q15560
BioGRIDTCEA2
STRING (EMBL)TCEA2
ZODIACTCEA2
Ontologies - Pathways
QuickGOQ15560
Ontology : AmiGODNA binding  protein binding  nucleoplasm  centrosome  DNA-templated transcription, elongation  transcription elongation factor complex  zinc ion binding  regulation of DNA-templated transcription, elongation  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBIDNA binding  protein binding  nucleoplasm  centrosome  DNA-templated transcription, elongation  transcription elongation factor complex  zinc ion binding  regulation of DNA-templated transcription, elongation  positive regulation of transcription by RNA polymerase II  
NDEx NetworkTCEA2
Atlas of Cancer Signalling NetworkTCEA2
Wikipedia pathwaysTCEA2
Orthology - Evolution
OrthoDB6919
GeneTree (enSembl)ENSG00000171703
Phylogenetic Trees/Animal Genes : TreeFamTCEA2
Homologs : HomoloGeneTCEA2
Homology/Alignments : Family Browser (UCSC)TCEA2
Gene fusions - Rearrangements
Fusion : QuiverTCEA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCEA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCEA2
dbVarTCEA2
ClinVarTCEA2
MonarchTCEA2
1000_GenomesTCEA2 
Exome Variant ServerTCEA2
GNOMAD BrowserENSG00000171703
Varsome BrowserTCEA2
ACMGTCEA2 variants
VarityQ15560
Genomic Variants (DGV)TCEA2 [DGVbeta]
DECIPHERTCEA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCEA2 
Mutations
ICGC Data PortalTCEA2 
TCGA Data PortalTCEA2 
Broad Tumor PortalTCEA2
OASIS PortalTCEA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCEA2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTCEA2
Mutations and Diseases : HGMDTCEA2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTCEA2
DgiDB (Drug Gene Interaction Database)TCEA2
DoCM (Curated mutations)TCEA2
CIViC (Clinical Interpretations of Variants in Cancer)TCEA2
Cancer3DTCEA2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604784   
Orphanet
DisGeNETTCEA2
MedgenTCEA2
Genetic Testing Registry TCEA2
NextProtQ15560 [Medical]
GENETestsTCEA2
Target ValidationTCEA2
Huge Navigator TCEA2 [HugePedia]
ClinGenTCEA2
Clinical trials, drugs, therapy
MyCancerGenomeTCEA2
Protein Interactions : CTDTCEA2
Pharm GKB GenePA36373
PharosQ15560
Clinical trialTCEA2
Miscellaneous
canSAR (ICR)TCEA2
HarmonizomeTCEA2
DataMed IndexTCEA2
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTCEA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:25:02 CEST 2021

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