TCF21 (transcription factor 21)

2007-02-01  

Identity

HGNC
LOCATION
6q23.2
LOCUSID
ALIAS
POD1,bHLHa23

Other Information

Locus ID:

NCBI: 6943
MIM: 603306
HGNC: 11632
Ensembl: ENSG00000118526

Variants:

dbSNP: 6943
ClinVar: 6943
TCGA: ENSG00000118526
COSMIC: TCF21

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118526ENST00000237316O43680
ENSG00000118526ENST00000367882O43680

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
250878722014Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.81
164151572006Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer.76
246761002014Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.39
238742382013Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus.35
209453272011Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers.30
217717272011Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.29
124937382003Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription.23
260202712015Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci.23
189786782008Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.21
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18

Citation

Dessen P

TCF21 (transcription factor 21)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45561/tcf21