Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TCFL5 (transcription factor like 5)

Identity

Alias_namestranscription factor-like 5 (basic helix-loop-helix)
Alias_symbol (synonym)Figlb
E2BP-1
CHA
bHLHe82
Other aliasSOSF1
HGNC (Hugo) TCFL5
LocusID (NCBI) 10732
Atlas_Id 55973
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 61482846 and ends at 61493115 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
APOD (3q29) / TCFL5 (20q13.33)DSTN (20p12.1) / TCFL5 (20q13.33)NCOA6 (20q11.22) / TCFL5 (20q13.33)
TAF4 (20q13.33) / TCFL5 (20q13.33)TCFL5 (20q13.33) / SNRPB (20p13)TCFL5 (20q13.33) / TCFL5 (20q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TCFL5   11646
Cards
Entrez_Gene (NCBI)TCFL5  10732  transcription factor like 5
AliasesCHA; E2BP-1; Figlb; SOSF1; 
bHLHe82
GeneCards (Weizmann)TCFL5
Ensembl hg19 (Hinxton)ENSG00000101190 [Gene_View]  chr20:61482846-61493115 [Contig_View]  TCFL5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101190 [Gene_View]  chr20:61482846-61493115 [Contig_View]  TCFL5 [Vega]
ICGC DataPortalENSG00000101190
TCGA cBioPortalTCFL5
AceView (NCBI)TCFL5
Genatlas (Paris)TCFL5
WikiGenes10732
SOURCE (Princeton)TCFL5
Genetics Home Reference (NIH)TCFL5
Genomic and cartography
GoldenPath hg19 (UCSC)TCFL5  -     chr20:61482846-61493115 -  20q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TCFL5  -     20q13.33   [Description]    (hg38-Dec_2013)
EnsemblTCFL5 - 20q13.33 [CytoView hg19]  TCFL5 - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBITCFL5 [Mapview hg19]  TCFL5 [Mapview hg38]
OMIM604745   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001301726 NM_006602
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TCFL5
Cluster EST : UnigeneHs.126248 [ NCBI ]
CGAP (NCI)Hs.126248
Alternative Splicing GalleryENSG00000101190
Gene ExpressionTCFL5 [ NCBI-GEO ]   TCFL5 [ EBI - ARRAY_EXPRESS ]   TCFL5 [ SEEK ]   TCFL5 [ MEM ]
Gene Expression Viewer (FireBrowse)TCFL5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10732
GTEX Portal (Tissue expression)TCFL5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UL49   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UL49  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UL49
Splice isoforms : SwissVarQ9UL49
PhosPhoSitePlusQ9UL49
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)TCFL5
DMDM Disease mutations10732
Blocks (Seattle)TCFL5
SuperfamilyQ9UL49
Human Protein AtlasENSG00000101190
Peptide AtlasQ9UL49
HPRD05297
IPIIPI00219462   IPI00873596   IPI00880158   IPI00384114   
Protein Interaction databases
DIP (DOE-UCLA)Q9UL49
IntAct (EBI)Q9UL49
FunCoupENSG00000101190
BioGRIDTCFL5
STRING (EMBL)TCFL5
ZODIACTCFL5
Ontologies - Pathways
QuickGOQ9UL49
Ontology : AmiGOmale germ cell nucleus  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  multicellular organism development  spermatogenesis  cell differentiation  regulation of cell proliferation  regulation of cell differentiation  protein dimerization activity  
Ontology : EGO-EBImale germ cell nucleus  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  multicellular organism development  spermatogenesis  cell differentiation  regulation of cell proliferation  regulation of cell differentiation  protein dimerization activity  
NDEx NetworkTCFL5
Atlas of Cancer Signalling NetworkTCFL5
Wikipedia pathwaysTCFL5
Orthology - Evolution
OrthoDB10732
GeneTree (enSembl)ENSG00000101190
Phylogenetic Trees/Animal Genes : TreeFamTCFL5
HOVERGENQ9UL49
HOGENOMQ9UL49
Homologs : HomoloGeneTCFL5
Homology/Alignments : Family Browser (UCSC)TCFL5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCFL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCFL5
dbVarTCFL5
ClinVarTCFL5
1000_GenomesTCFL5 
Exome Variant ServerTCFL5
ExAC (Exome Aggregation Consortium)TCFL5 (select the gene name)
Genetic variants : HAPMAP10732
Genomic Variants (DGV)TCFL5 [DGVbeta]
DECIPHER (Syndromes)20:61482846-61493115  ENSG00000101190
CONAN: Copy Number AnalysisTCFL5 
Mutations
ICGC Data PortalTCFL5 
TCGA Data PortalTCFL5 
Broad Tumor PortalTCFL5
OASIS PortalTCFL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCFL5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTCFL5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TCFL5
DgiDB (Drug Gene Interaction Database)TCFL5
DoCM (Curated mutations)TCFL5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TCFL5 (select a term)
intoGenTCFL5
Cancer3DTCFL5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604745   
Orphanet
MedgenTCFL5
Genetic Testing Registry TCFL5
NextProtQ9UL49 [Medical]
TSGene10732
GENETestsTCFL5
Huge Navigator TCFL5 [HugePedia]
snp3D : Map Gene to Disease10732
BioCentury BCIQTCFL5
ClinGenTCFL5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10732
Chemical/Pharm GKB GenePA36398
Clinical trialTCFL5
Miscellaneous
canSAR (ICR)TCFL5 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTCFL5
EVEXTCFL5
GoPubMedTCFL5
iHOPTCFL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:30:38 CET 2017

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