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TCFL5 (transcription factor like 5)

Identity

Alias (NCBI)CHA
E2BP-1
Figlb
SOSF1
bHLHe82
HGNC (Hugo) TCFL5
HGNC Alias symbFiglb
E2BP-1
CHA
bHLHe82
HGNC Alias nameHPV-16 E2 binding protein 1
HGNC Previous nametranscription factor-like 5 (basic helix-loop-helix)
LocusID (NCBI) 10732
Atlas_Id 55973
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 62841005 and ends at 62861822 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APOD (3q29) / TCFL5 (20q13.33)DSTN (20p12.1) / TCFL5 (20q13.33)NCOA6 (20q11.22) / TCFL5 (20q13.33)
TAF4 (20q13.33) / TCFL5 (20q13.33)TCFL5 (20q13.33) / SNRPB (20p13)TCFL5 (20q13.33) / TCFL5 (20q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TCFL5   11646
Cards
Entrez_Gene (NCBI)TCFL5    transcription factor like 5
AliasesCHA; E2BP-1; Figlb; SOSF1; 
bHLHe82
GeneCards (Weizmann)TCFL5
Ensembl hg19 (Hinxton)ENSG00000101190 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101190 [Gene_View]  ENSG00000101190 [Sequence]  chr20:62841005-62861822 [Contig_View]  TCFL5 [Vega]
ICGC DataPortalENSG00000101190
TCGA cBioPortalTCFL5
AceView (NCBI)TCFL5
Genatlas (Paris)TCFL5
SOURCE (Princeton)TCFL5
Genetics Home Reference (NIH)TCFL5
Genomic and cartography
GoldenPath hg38 (UCSC)TCFL5  -     chr20:62841005-62861822 -  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCFL5  -     20q13.33   [Description]    (hg19-Feb_2009)
GoldenPathTCFL5 - 20q13.33 [CytoView hg19]  TCFL5 - 20q13.33 [CytoView hg38]
ImmunoBaseENSG00000101190
Genome Data Viewer NCBITCFL5 [Mapview hg19]  
OMIM604745   
Gene and transcription
Genbank (Entrez)AB012124 AF070992 AJ271337 BC015689 BC046933
RefSeq transcript (Entrez)NM_001301726 NM_006602
Consensus coding sequences : CCDS (NCBI)TCFL5
Gene ExpressionTCFL5 [ NCBI-GEO ]   TCFL5 [ EBI - ARRAY_EXPRESS ]   TCFL5 [ SEEK ]   TCFL5 [ MEM ]
Gene Expression Viewer (FireBrowse)TCFL5 [ Firebrowse - Broad ]
GenevisibleExpression of TCFL5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10732
GTEX Portal (Tissue expression)TCFL5
Human Protein AtlasENSG00000101190-TCFL5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UL49   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UL49  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UL49
PhosPhoSitePlusQ9UL49
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    HLH_DNA-bd_sf    TCFL5   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)TCFL5
SuperfamilyQ9UL49
AlphaFold pdb e-kbQ9UL49   
Human Protein Atlas [tissue]ENSG00000101190-TCFL5 [tissue]
HPRD05297
Protein Interaction databases
DIP (DOE-UCLA)Q9UL49
IntAct (EBI)Q9UL49
BioGRIDTCFL5
STRING (EMBL)TCFL5
ZODIACTCFL5
Ontologies - Pathways
QuickGOQ9UL49
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  male germ cell nucleus  DNA binding  DNA-binding transcription factor activity  nucleus  nucleus  regulation of transcription, DNA-templated  regulation of transcription, DNA-templated  transcription by RNA polymerase II  multicellular organism development  spermatogenesis  cell differentiation  regulation of cell population proliferation  regulation of cell differentiation  protein dimerization activity  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  male germ cell nucleus  DNA binding  DNA-binding transcription factor activity  nucleus  nucleus  regulation of transcription, DNA-templated  regulation of transcription, DNA-templated  transcription by RNA polymerase II  multicellular organism development  spermatogenesis  cell differentiation  regulation of cell population proliferation  regulation of cell differentiation  protein dimerization activity  sequence-specific double-stranded DNA binding  
NDEx NetworkTCFL5
Atlas of Cancer Signalling NetworkTCFL5
Wikipedia pathwaysTCFL5
Orthology - Evolution
OrthoDB10732
GeneTree (enSembl)ENSG00000101190
Phylogenetic Trees/Animal Genes : TreeFamTCFL5
Homologs : HomoloGeneTCFL5
Homology/Alignments : Family Browser (UCSC)TCFL5
Gene fusions - Rearrangements
Fusion : QuiverTCFL5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCFL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCFL5
dbVarTCFL5
ClinVarTCFL5
MonarchTCFL5
1000_GenomesTCFL5 
Exome Variant ServerTCFL5
GNOMAD BrowserENSG00000101190
Varsome BrowserTCFL5
ACMGTCFL5 variants
VarityQ9UL49
Genomic Variants (DGV)TCFL5 [DGVbeta]
DECIPHERTCFL5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCFL5 
Mutations
ICGC Data PortalTCFL5 
TCGA Data PortalTCFL5 
Broad Tumor PortalTCFL5
OASIS PortalTCFL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCFL5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTCFL5
Mutations and Diseases : HGMDTCFL5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTCFL5
DgiDB (Drug Gene Interaction Database)TCFL5
DoCM (Curated mutations)TCFL5
CIViC (Clinical Interpretations of Variants in Cancer)TCFL5
Cancer3DTCFL5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604745   
Orphanet
DisGeNETTCFL5
MedgenTCFL5
Genetic Testing Registry TCFL5
NextProtQ9UL49 [Medical]
GENETestsTCFL5
Target ValidationTCFL5
Huge Navigator TCFL5 [HugePedia]
ClinGenTCFL5
Clinical trials, drugs, therapy
MyCancerGenomeTCFL5
Protein Interactions : CTDTCFL5
Pharm GKB GenePA36398
PharosQ9UL49
Clinical trialTCFL5
Miscellaneous
canSAR (ICR)TCFL5
HarmonizomeTCFL5
DataMed IndexTCFL5
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTCFL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:34:35 CEST 2021

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