Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TCIRG1 (T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3)

Identity

Alias_namesT-cell, immune regulator 1
T-cell, immune regulator 1, ATPase, H transporting, lysosomal V0 protein a isoform 3
T-cell, immune regulator 1, ATPase, H transporting, lysosomal V0 subunit A3
Alias_symbol (synonym)TIRC7
OC-116
OC116
ATP6N1C
Atp6i
a3
ATP6V0A3
Other aliasOC-116kDa
OPTB1
Stv1
Vph1
HGNC (Hugo) TCIRG1
LocusID (NCBI) 10312
Atlas_Id 53799
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 68038995 and ends at 68050899 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALKBH3 (11p11.2) / TCIRG1 (11q13.2)TCIRG1 (11q13.2) / CNIH1 (14q22.2)WWP2 (16q22.1) / TCIRG1 (11q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TCIRG1   11647
LRG (Locus Reference Genomic)LRG_115
Cards
Entrez_Gene (NCBI)TCIRG1  10312  T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3
AliasesATP6N1C; ATP6V0A3; Atp6i; OC-116kDa; 
OC116; OPTB1; Stv1; TIRC7; Vph1; a3
GeneCards (Weizmann)TCIRG1
Ensembl hg19 (Hinxton)ENSG00000110719 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110719 [Gene_View]  chr11:68038995-68050899 [Contig_View]  TCIRG1 [Vega]
ICGC DataPortalENSG00000110719
TCGA cBioPortalTCIRG1
AceView (NCBI)TCIRG1
Genatlas (Paris)TCIRG1
WikiGenes10312
SOURCE (Princeton)TCIRG1
Genetics Home Reference (NIH)TCIRG1
Genomic and cartography
GoldenPath hg38 (UCSC)TCIRG1  -     chr11:68038995-68050899 +  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCIRG1  -     11q13.2   [Description]    (hg19-Feb_2009)
EnsemblTCIRG1 - 11q13.2 [CytoView hg19]  TCIRG1 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBITCIRG1 [Mapview hg19]  TCIRG1 [Mapview hg38]
OMIM259700   604592   
Gene and transcription
Genbank (Entrez)AA625923 AF025374 AF497545 AK057093 AW083897
RefSeq transcript (Entrez)NM_006019 NM_006053
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TCIRG1
Cluster EST : UnigeneHs.716672 [ NCBI ]
CGAP (NCI)Hs.716672
Alternative Splicing GalleryENSG00000110719
Gene ExpressionTCIRG1 [ NCBI-GEO ]   TCIRG1 [ EBI - ARRAY_EXPRESS ]   TCIRG1 [ SEEK ]   TCIRG1 [ MEM ]
Gene Expression Viewer (FireBrowse)TCIRG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10312
GTEX Portal (Tissue expression)TCIRG1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13488   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13488  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13488
Splice isoforms : SwissVarQ13488
PhosPhoSitePlusQ13488
Domains : Interpro (EBI)V-ATPase_116kDa_su    V-type_ATPase_116kDa_su_euka   
Domain families : Pfam (Sanger)V_ATPase_I (PF01496)   
Domain families : Pfam (NCBI)pfam01496   
Conserved Domain (NCBI)TCIRG1
DMDM Disease mutations10312
Blocks (Seattle)TCIRG1
SuperfamilyQ13488
Human Protein AtlasENSG00000110719
Peptide AtlasQ13488
HPRD05207
IPIIPI00299719   IPI00219663   IPI00980504   IPI00868989   IPI00980862   IPI00979366   IPI00978644   IPI00975902   IPI00981373   
Protein Interaction databases
DIP (DOE-UCLA)Q13488
IntAct (EBI)Q13488
FunCoupENSG00000110719
BioGRIDTCIRG1
STRING (EMBL)TCIRG1
ZODIACTCIRG1
Ontologies - Pathways
QuickGOQ13488
Ontology : AmiGOvacuolar proton-transporting V-type ATPase, V0 domain  transporter activity  mitochondrion  lysosomal membrane  plasma membrane  integral component of plasma membrane  cellular defense response  vacuolar acidification  protein catabolic process in the vacuole  positive regulation of cell proliferation  insulin receptor signaling pathway  endosome membrane  ATP synthesis coupled proton transport  ATP hydrolysis coupled proton transport  proton transport  macroautophagy  apical plasma membrane  vacuolar proton-transporting V-type ATPase complex  phagocytic vesicle membrane  transferrin transport  ion transmembrane transport  neutrophil degranulation  proton-transporting ATPase activity, rotational mechanism  ATPase binding  vacuolar proton-transporting V-type ATPase complex assembly  phagosome acidification  ficolin-1-rich granule membrane  
Ontology : EGO-EBIvacuolar proton-transporting V-type ATPase, V0 domain  transporter activity  mitochondrion  lysosomal membrane  plasma membrane  integral component of plasma membrane  cellular defense response  vacuolar acidification  protein catabolic process in the vacuole  positive regulation of cell proliferation  insulin receptor signaling pathway  endosome membrane  ATP synthesis coupled proton transport  ATP hydrolysis coupled proton transport  proton transport  macroautophagy  apical plasma membrane  vacuolar proton-transporting V-type ATPase complex  phagocytic vesicle membrane  transferrin transport  ion transmembrane transport  neutrophil degranulation  proton-transporting ATPase activity, rotational mechanism  ATPase binding  vacuolar proton-transporting V-type ATPase complex assembly  phagosome acidification  ficolin-1-rich granule membrane  
Pathways : KEGG   
NDEx NetworkTCIRG1
Atlas of Cancer Signalling NetworkTCIRG1
Wikipedia pathwaysTCIRG1
Orthology - Evolution
OrthoDB10312
GeneTree (enSembl)ENSG00000110719
Phylogenetic Trees/Animal Genes : TreeFamTCIRG1
HOVERGENQ13488
HOGENOMQ13488
Homologs : HomoloGeneTCIRG1
Homology/Alignments : Family Browser (UCSC)TCIRG1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCIRG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCIRG1
dbVarTCIRG1
ClinVarTCIRG1
1000_GenomesTCIRG1 
Exome Variant ServerTCIRG1
ExAC (Exome Aggregation Consortium)TCIRG1 (select the gene name)
Genetic variants : HAPMAP10312
Genomic Variants (DGV)TCIRG1 [DGVbeta]
DECIPHERTCIRG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCIRG1 
Mutations
ICGC Data PortalTCIRG1 
TCGA Data PortalTCIRG1 
Broad Tumor PortalTCIRG1
OASIS PortalTCIRG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCIRG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTCIRG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TCIRG1
DgiDB (Drug Gene Interaction Database)TCIRG1
DoCM (Curated mutations)TCIRG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TCIRG1 (select a term)
intoGenTCIRG1
Cancer3DTCIRG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM259700    604592   
Orphanet822    2530   
MedgenTCIRG1
Genetic Testing Registry TCIRG1
NextProtQ13488 [Medical]
TSGene10312
GENETestsTCIRG1
Target ValidationTCIRG1
Huge Navigator TCIRG1 [HugePedia]
snp3D : Map Gene to Disease10312
BioCentury BCIQTCIRG1
ClinGenTCIRG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10312
Chemical/Pharm GKB GenePA36399
Clinical trialTCIRG1
Miscellaneous
canSAR (ICR)TCIRG1 (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTCIRG1
EVEXTCIRG1
GoPubMedTCIRG1
iHOPTCIRG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:58:54 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.