Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TCIRG1 (T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3)

Identity

Other namesATP6N1C
ATP6V0A3
Atp6i
OC-116kDa
OC116
OPTB1
Stv1
TIRC7
Vph1
a3
HGNC (Hugo) TCIRG1
LocusID (NCBI) 10312
Location 11q13.2
Location_base_pair Starts at 67806462 and ends at 67818366 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)TCIRG1   11647
Cards
Entrez_Gene (NCBI)TCIRG1  10312  T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
GeneCards (Weizmann)TCIRG1
Ensembl (Hinxton)ENSG00000110719 [Gene_View]  chr11:67806462-67818366 [Contig_View]  TCIRG1 [Vega]
ICGC DataPortalENSG00000110719
cBioPortalTCIRG1
AceView (NCBI)TCIRG1
Genatlas (Paris)TCIRG1
WikiGenes10312
SOURCE (Princeton)NM_006019 NM_006053
Genomic and cartography
GoldenPath (UCSC)TCIRG1  -  11q13.2   chr11:67806462-67818366 +  11q13.2   [Description]    (hg19-Feb_2009)
EnsemblTCIRG1 - 11q13.2 [CytoView]
Mapping of homologs : NCBITCIRG1 [Mapview]
OMIM259700   604592   
Gene and transcription
Genbank (Entrez)AA625923 AF025374 AF497545 AW083897 AY548967
RefSeq transcript (Entrez)NM_006019 NM_006053
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_007878 NT_167190 NW_001838025 NW_004929380
Consensus coding sequences : CCDS (NCBI)TCIRG1
Cluster EST : UnigeneHs.495985 [ NCBI ]
CGAP (NCI)Hs.495985
Alternative Splicing GalleryENSG00000110719
Gene ExpressionTCIRG1 [ NCBI-GEO ]     TCIRG1 [ SEEK ]   TCIRG1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13488 (Uniprot)
NextProtQ13488  [Medical]
With graphics : InterProQ13488
Splice isoforms : SwissVarQ13488 (Swissvar)
Domains : Interpro (EBI)V-ATPase_116kDa_su [organisation]   V-type_ATPase_116kDa_su_euka [organisation]  
Related proteins : CluSTrQ13488
Domain families : Pfam (Sanger)V_ATPase_I (PF01496)   
Domain families : Pfam (NCBI)pfam01496   
DMDM Disease mutations10312
Blocks (Seattle)Q13488
Human Protein AtlasENSG00000110719 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ13488
HPRD05207
IPIIPI00299719   IPI00219663   IPI00980504   IPI00868989   IPI00980862   IPI00979366   IPI00978644   IPI00975902   IPI00981373   
Protein Interaction databases
DIP (DOE-UCLA)Q13488
IntAct (EBI)Q13488
FunCoupENSG00000110719
BioGRIDTCIRG1
InParanoidQ13488
Interologous Interaction database Q13488
IntegromeDBTCIRG1
STRING (EMBL)TCIRG1
Ontologies - Pathways
Ontology : AmiGOvacuolar proton-transporting V-type ATPase, V0 domain  transporter activity  mitochondrion  lysosomal membrane  plasma membrane  integral component of plasma membrane  cellular iron ion homeostasis  cellular defense response  positive regulation of cell proliferation  insulin receptor signaling pathway  endosome membrane  hydrogen ion transmembrane transporter activity  ATP hydrolysis coupled proton transport  proton transport  apical plasma membrane  phagocytic vesicle membrane  transferrin transport  interaction with host  transmembrane transport  phagosome maturation  
Ontology : EGO-EBIvacuolar proton-transporting V-type ATPase, V0 domain  transporter activity  mitochondrion  lysosomal membrane  plasma membrane  integral component of plasma membrane  cellular iron ion homeostasis  cellular defense response  positive regulation of cell proliferation  insulin receptor signaling pathway  endosome membrane  hydrogen ion transmembrane transporter activity  ATP hydrolysis coupled proton transport  proton transport  apical plasma membrane  phagocytic vesicle membrane  transferrin transport  interaction with host  transmembrane transport  phagosome maturation  
Pathways : KEGGOxidative phosphorylation    Lysosome    Phagosome    Synaptic vesicle cycle    Collecting duct acid secretion    Vibrio cholerae infection    Epithelial cell signaling in Helicobacter pylori infection    Tuberculosis    Rheumatoid arthritis   
Protein Interaction DatabaseTCIRG1
Wikipedia pathwaysTCIRG1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TCIRG1
snp3D : Map Gene to Disease10312
SNP (GeneSNP Utah)TCIRG1
SNP : HGBaseTCIRG1
Genetic variants : HAPMAPTCIRG1
Exome VariantTCIRG1
1000_GenomesTCIRG1 
ICGC programENSG00000110719 
Somatic Mutations in Cancer : COSMICTCIRG1 
CONAN: Copy Number AnalysisTCIRG1 
Mutations and Diseases : HGMDTCIRG1
Mutations and Diseases : intOGenTCIRG1
Genomic VariantsTCIRG1  TCIRG1 [DGVbeta]
dbVarTCIRG1
ClinVarTCIRG1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM259700    604592   
MedgenTCIRG1
GENETestsTCIRG1
Disease Genetic AssociationTCIRG1
Huge Navigator TCIRG1 [HugePedia]  TCIRG1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTCIRG1
Homology/Alignments : Family Browser (UCSC)TCIRG1
Phylogenetic Trees/Animal Genes : TreeFamTCIRG1
Chemical/Protein Interactions : CTD10312
Chemical/Pharm GKB GenePA36399
Clinical trialTCIRG1
Cancer Resource (Charite)ENSG00000110719
Other databases
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
CoreMineTCIRG1
iHOPTCIRG1
OncoSearchTCIRG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:07:13 CEST 2014

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