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TCP10L (t-complex 10 like)

Identity

Alias (NCBI)C21orf77
LINC00846
PRED77
TCP10A-1
TCP10A-2
HGNC (Hugo) TCP10L
HGNC Alias symbPRED77
HGNC Previous namet-complex 10 (a murine tcp homolog)-like
 t-complex 10 (mouse)-like
LocusID (NCBI) 140290
Atlas_Id 53963
Location 21q22.11  [Link to chromosome band 21q22]
Location_base_pair Starts at 32573721 and ends at 32585523 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TCP10L   11657
Cards
Entrez_Gene (NCBI)TCP10L    t-complex 10 like
AliasesC21orf77; LINC00846; PRED77; TCP10A-1; 
TCP10A-2
GeneCards (Weizmann)TCP10L
Ensembl hg19 (Hinxton)ENSG00000242220 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000242220 [Gene_View]  ENSG00000242220 [Sequence]  chr21:32573721-32585523 [Contig_View]  TCP10L [Vega]
ICGC DataPortalENSG00000242220
TCGA cBioPortalTCP10L
AceView (NCBI)TCP10L
Genatlas (Paris)TCP10L
SOURCE (Princeton)TCP10L
Genetics Home Reference (NIH)TCP10L
Genomic and cartography
GoldenPath hg38 (UCSC)TCP10L  -     chr21:32573721-32585523 -  21q22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCP10L  -     21q22.11   [Description]    (hg19-Feb_2009)
GoldenPathTCP10L - 21q22.11 [CytoView hg19]  TCP10L - 21q22.11 [CytoView hg38]
ImmunoBaseENSG00000242220
Genome Data Viewer NCBITCP10L [Mapview hg19]  
OMIM608365   
Gene and transcription
Genbank (Entrez)AF115967 AK001794 AK058078 AK223529 BC022024
RefSeq transcript (Entrez)NM_018277 NM_144659
Consensus coding sequences : CCDS (NCBI)TCP10L
Gene ExpressionTCP10L [ NCBI-GEO ]   TCP10L [ EBI - ARRAY_EXPRESS ]   TCP10L [ SEEK ]   TCP10L [ MEM ]
Gene Expression Viewer (FireBrowse)TCP10L [ Firebrowse - Broad ]
GenevisibleExpression of TCP10L in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140290
GTEX Portal (Tissue expression)TCP10L
Human Protein AtlasENSG00000242220-TCP10L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TDR4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TDR4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TDR4
PhosPhoSitePlusQ8TDR4
Domains : Interpro (EBI)TCP10_fam   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TCP10L
SuperfamilyQ8TDR4
AlphaFold pdb e-kbQ8TDR4   
Human Protein Atlas [tissue]ENSG00000242220-TCP10L [tissue]
HPRD10518
Protein Interaction databases
DIP (DOE-UCLA)Q8TDR4
IntAct (EBI)Q8TDR4
BioGRIDTCP10L
STRING (EMBL)TCP10L
ZODIACTCP10L
Ontologies - Pathways
QuickGOQ8TDR4
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  transcription corepressor activity  transcription corepressor activity  protein binding  nucleus  nucleus  centriole  identical protein binding  protein self-association  DNA-binding transcription factor binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  transcription corepressor activity  transcription corepressor activity  protein binding  nucleus  nucleus  centriole  identical protein binding  protein self-association  DNA-binding transcription factor binding  
NDEx NetworkTCP10L
Atlas of Cancer Signalling NetworkTCP10L
Wikipedia pathwaysTCP10L
Orthology - Evolution
OrthoDB140290
GeneTree (enSembl)ENSG00000242220
Phylogenetic Trees/Animal Genes : TreeFamTCP10L
Homologs : HomoloGeneTCP10L
Homology/Alignments : Family Browser (UCSC)TCP10L
Gene fusions - Rearrangements
Fusion : QuiverTCP10L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCP10L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCP10L
dbVarTCP10L
ClinVarTCP10L
MonarchTCP10L
1000_GenomesTCP10L 
Exome Variant ServerTCP10L
GNOMAD BrowserENSG00000242220
Varsome BrowserTCP10L
ACMGTCP10L variants
VarityQ8TDR4
Genomic Variants (DGV)TCP10L [DGVbeta]
DECIPHERTCP10L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCP10L 
Mutations
ICGC Data PortalTCP10L 
TCGA Data PortalTCP10L 
Broad Tumor PortalTCP10L
OASIS PortalTCP10L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCP10L  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTCP10L
Mutations and Diseases : HGMDTCP10L
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTCP10L
DgiDB (Drug Gene Interaction Database)TCP10L
DoCM (Curated mutations)TCP10L
CIViC (Clinical Interpretations of Variants in Cancer)TCP10L
Cancer3DTCP10L
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608365   
Orphanet
DisGeNETTCP10L
MedgenTCP10L
Genetic Testing Registry TCP10L
NextProtQ8TDR4 [Medical]
GENETestsTCP10L
Target ValidationTCP10L
Huge Navigator TCP10L [HugePedia]
ClinGenTCP10L
Clinical trials, drugs, therapy
MyCancerGenomeTCP10L
Protein Interactions : CTDTCP10L
Pharm GKB GenePA36408
PharosQ8TDR4
Clinical trialTCP10L
Miscellaneous
canSAR (ICR)TCP10L
HarmonizomeTCP10L
DataMed IndexTCP10L
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTCP10L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:38 CEST 2021

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