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TCTN1 (tectonic family member 1)

Identity

Alias (NCBI)JBTS13
TECT1
HGNC (Hugo) TCTN1
HGNC Alias symbFLJ21127
TECT1
JBTS13
LocusID (NCBI) 79600
Atlas_Id 55624
Location 12q24.11  [Link to chromosome band 12q24]
Location_base_pair Starts at 110614129 and ends at 110649430 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
S100B (21q22.3) / TCTN1 (12q24.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TCTN1   26113
Cards
Entrez_Gene (NCBI)TCTN1    tectonic family member 1
AliasesJBTS13; TECT1
GeneCards (Weizmann)TCTN1
Ensembl hg19 (Hinxton)ENSG00000204852 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204852 [Gene_View]  ENSG00000204852 [Sequence]  chr12:110614129-110649430 [Contig_View]  TCTN1 [Vega]
ICGC DataPortalENSG00000204852
TCGA cBioPortalTCTN1
AceView (NCBI)TCTN1
Genatlas (Paris)TCTN1
SOURCE (Princeton)TCTN1
Genetics Home Reference (NIH)TCTN1
Genomic and cartography
GoldenPath hg38 (UCSC)TCTN1  -     chr12:110614129-110649430 +  12q24.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCTN1  -     12q24.11   [Description]    (hg19-Feb_2009)
GoldenPathTCTN1 - 12q24.11 [CytoView hg19]  TCTN1 - 12q24.11 [CytoView hg38]
ImmunoBaseENSG00000204852
Genome Data Viewer NCBITCTN1 [Mapview hg19]  
OMIM609863   614173   
Gene and transcription
Genbank (Entrez)AK024780 AK055891 AK092775 AK128417 AK295514
RefSeq transcript (Entrez)NM_001082537 NM_001082538 NM_001173975 NM_001173976 NM_001319680 NM_001319681 NM_001319682 NM_024549
Consensus coding sequences : CCDS (NCBI)TCTN1
Gene ExpressionTCTN1 [ NCBI-GEO ]   TCTN1 [ EBI - ARRAY_EXPRESS ]   TCTN1 [ SEEK ]   TCTN1 [ MEM ]
Gene Expression Viewer (FireBrowse)TCTN1 [ Firebrowse - Broad ]
GenevisibleExpression of TCTN1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79600
GTEX Portal (Tissue expression)TCTN1
Human Protein AtlasENSG00000204852-TCTN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2MV58   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2MV58  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2MV58
PhosPhoSitePlusQ2MV58
Domains : Interpro (EBI)DUF1619    Tectonic   
Domain families : Pfam (Sanger)DUF1619 (PF07773)   
Domain families : Pfam (NCBI)pfam07773   
Conserved Domain (NCBI)TCTN1
SuperfamilyQ2MV58
AlphaFold pdb e-kbQ2MV58   
Human Protein Atlas [tissue]ENSG00000204852-TCTN1 [tissue]
HPRD08636
Protein Interaction databases
DIP (DOE-UCLA)Q2MV58
IntAct (EBI)Q2MV58
BioGRIDTCTN1
STRING (EMBL)TCTN1
ZODIACTCTN1
Ontologies - Pathways
QuickGOQ2MV58
Ontology : AmiGOin utero embryonic development  neural tube formation  extracellular space  cytosol  cytoskeleton  regulation of smoothened signaling pathway  membrane  somatic motor neuron differentiation  telencephalon development  dorsal/ventral neural tube patterning  central nervous system interneuron axonogenesis  MKS complex  MKS complex  cilium assembly  cilium assembly  ciliary basal body-plasma membrane docking  protein localization to ciliary transition zone  
Ontology : EGO-EBIin utero embryonic development  neural tube formation  extracellular space  cytosol  cytoskeleton  regulation of smoothened signaling pathway  membrane  somatic motor neuron differentiation  telencephalon development  dorsal/ventral neural tube patterning  central nervous system interneuron axonogenesis  MKS complex  MKS complex  cilium assembly  cilium assembly  ciliary basal body-plasma membrane docking  protein localization to ciliary transition zone  
NDEx NetworkTCTN1
Atlas of Cancer Signalling NetworkTCTN1
Wikipedia pathwaysTCTN1
Orthology - Evolution
OrthoDB79600
GeneTree (enSembl)ENSG00000204852
Phylogenetic Trees/Animal Genes : TreeFamTCTN1
Homologs : HomoloGeneTCTN1
Homology/Alignments : Family Browser (UCSC)TCTN1
Gene fusions - Rearrangements
Fusion : QuiverTCTN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCTN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCTN1
dbVarTCTN1
ClinVarTCTN1
MonarchTCTN1
1000_GenomesTCTN1 
Exome Variant ServerTCTN1
GNOMAD BrowserENSG00000204852
Varsome BrowserTCTN1
ACMGTCTN1 variants
VarityQ2MV58
Genomic Variants (DGV)TCTN1 [DGVbeta]
DECIPHERTCTN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCTN1 
Mutations
ICGC Data PortalTCTN1 
TCGA Data PortalTCTN1 
Broad Tumor PortalTCTN1
OASIS PortalTCTN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCTN1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTCTN1
Mutations and Diseases : HGMDTCTN1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTCTN1
DgiDB (Drug Gene Interaction Database)TCTN1
DoCM (Curated mutations)TCTN1
CIViC (Clinical Interpretations of Variants in Cancer)TCTN1
Cancer3DTCTN1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609863    614173   
Orphanet1022   
DisGeNETTCTN1
MedgenTCTN1
Genetic Testing Registry TCTN1
NextProtQ2MV58 [Medical]
GENETestsTCTN1
Target ValidationTCTN1
Huge Navigator TCTN1 [HugePedia]
ClinGenTCTN1 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeTCTN1
Protein Interactions : CTDTCTN1
Pharm GKB GenePA162405437
PharosQ2MV58
Clinical trialTCTN1
Miscellaneous
canSAR (ICR)TCTN1
HarmonizomeTCTN1
DataMed IndexTCTN1
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTCTN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:39 CEST 2021

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