Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TCTN2 (tectonic family member 2)

Identity

Alias (NCBI)C12orf38
JBTS24
MKS8
TECT2
HGNC (Hugo) TCTN2
HGNC Alias symbFLJ12975
TECT2
MKS8
JBTS24
HGNC Alias nameMeckel syndrome, type 8
HGNC Previous nameC12orf38
HGNC Previous namechromosome 12 open reading frame 38
LocusID (NCBI) 79867
Atlas_Id 74596
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 123671113 and ends at 123708397 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TCTN2 (12q24.31) / TMEM62 (15q15.2)TCTN2 (12q24.31) / WNK1 (12p13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TCTN2   25774
Cards
Entrez_Gene (NCBI)TCTN2    tectonic family member 2
AliasesC12orf38; JBTS24; MKS8; TECT2
GeneCards (Weizmann)TCTN2
Ensembl hg19 (Hinxton)ENSG00000168778 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168778 [Gene_View]  ENSG00000168778 [Sequence]  chr12:123671113-123708397 [Contig_View]  TCTN2 [Vega]
ICGC DataPortalENSG00000168778
TCGA cBioPortalTCTN2
AceView (NCBI)TCTN2
Genatlas (Paris)TCTN2
SOURCE (Princeton)TCTN2
Genetics Home Reference (NIH)TCTN2
Genomic and cartography
GoldenPath hg38 (UCSC)TCTN2  -     chr12:123671113-123708397 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCTN2  -     12q24.31   [Description]    (hg19-Feb_2009)
GoldenPathTCTN2 - 12q24.31 [CytoView hg19]  TCTN2 - 12q24.31 [CytoView hg38]
ImmunoBaseENSG00000168778
Genome Data Viewer NCBITCTN2 [Mapview hg19]  
OMIM613846   613885   616654   
Gene and transcription
Genbank (Entrez)AK023037 AK056924 AK292153 BC009112 BM997327
RefSeq transcript (Entrez)NM_001143850 NM_024809
Consensus coding sequences : CCDS (NCBI)TCTN2
Gene ExpressionTCTN2 [ NCBI-GEO ]   TCTN2 [ EBI - ARRAY_EXPRESS ]   TCTN2 [ SEEK ]   TCTN2 [ MEM ]
Gene Expression Viewer (FireBrowse)TCTN2 [ Firebrowse - Broad ]
GenevisibleExpression of TCTN2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79867
GTEX Portal (Tissue expression)TCTN2
Human Protein AtlasENSG00000168778-TCTN2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GX1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GX1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GX1
PhosPhoSitePlusQ96GX1
Domains : Interpro (EBI)DUF1619    Tectonic   
Domain families : Pfam (Sanger)DUF1619 (PF07773)   
Domain families : Pfam (NCBI)pfam07773   
Conserved Domain (NCBI)TCTN2
SuperfamilyQ96GX1
AlphaFold pdb e-kbQ96GX1   
Human Protein Atlas [tissue]ENSG00000168778-TCTN2 [tissue]
HPRD07805
Protein Interaction databases
DIP (DOE-UCLA)Q96GX1
IntAct (EBI)Q96GX1
BioGRIDTCTN2
STRING (EMBL)TCTN2
ZODIACTCTN2
Ontologies - Pathways
QuickGOQ96GX1
Ontology : AmiGOcytoplasm  cytoskeleton  smoothened signaling pathway  smoothened signaling pathway  integral component of membrane  MKS complex  MKS complex  ciliary membrane  cilium assembly  cilium assembly  ciliary basal body-plasma membrane docking  protein localization to ciliary transition zone  
Ontology : EGO-EBIcytoplasm  cytoskeleton  smoothened signaling pathway  smoothened signaling pathway  integral component of membrane  MKS complex  MKS complex  ciliary membrane  cilium assembly  cilium assembly  ciliary basal body-plasma membrane docking  protein localization to ciliary transition zone  
NDEx NetworkTCTN2
Atlas of Cancer Signalling NetworkTCTN2
Wikipedia pathwaysTCTN2
Orthology - Evolution
OrthoDB79867
GeneTree (enSembl)ENSG00000168778
Phylogenetic Trees/Animal Genes : TreeFamTCTN2
Homologs : HomoloGeneTCTN2
Homology/Alignments : Family Browser (UCSC)TCTN2
Gene fusions - Rearrangements
Fusion : QuiverTCTN2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCTN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCTN2
dbVarTCTN2
ClinVarTCTN2
MonarchTCTN2
1000_GenomesTCTN2 
Exome Variant ServerTCTN2
GNOMAD BrowserENSG00000168778
Varsome BrowserTCTN2
ACMGTCTN2 variants
VarityQ96GX1
Genomic Variants (DGV)TCTN2 [DGVbeta]
DECIPHERTCTN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCTN2 
Mutations
ICGC Data PortalTCTN2 
TCGA Data PortalTCTN2 
Broad Tumor PortalTCTN2
OASIS PortalTCTN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCTN2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTCTN2
Mutations and Diseases : HGMDTCTN2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTCTN2
DgiDB (Drug Gene Interaction Database)TCTN2
DoCM (Curated mutations)TCTN2
CIViC (Clinical Interpretations of Variants in Cancer)TCTN2
Cancer3DTCTN2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613846    613885    616654   
Orphanet280    1022   
DisGeNETTCTN2
MedgenTCTN2
Genetic Testing Registry TCTN2
NextProtQ96GX1 [Medical]
GENETestsTCTN2
Target ValidationTCTN2
Huge Navigator TCTN2 [HugePedia]
ClinGenTCTN2
Clinical trials, drugs, therapy
MyCancerGenomeTCTN2
Protein Interactions : CTDTCTN2
Pharm GKB GenePA162405472
PharosQ96GX1
Clinical trialTCTN2
Miscellaneous
canSAR (ICR)TCTN2
HarmonizomeTCTN2
DataMed IndexTCTN2
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTCTN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:25:06 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.