Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TDG (thymine-DNA glycosylase)

Identity

Other names-
HGNC (Hugo) TDG
LocusID (NCBI) 6996
Location 12q23.3
Location_base_pair Starts at 104359593 and ends at 104382656 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TDG   11700
Entrez_Gene (NCBI)TDG  6996  thymine-DNA glycosylase
Cards
GeneCards (Weizmann)TDG
Ensembl (Hinxton)ENSG00000139372 [Gene_View]  chr12:104359593-104382656 [Contig_View]  TDG [Vega]
AceView (NCBI)TDG
Genatlas (Paris)TDG
SOURCE (Stanford)NM_001008411 NM_003211
Genomic and cartography
GoldenPath (UCSC)TDG  -  12q23.3   chr12:104359593-104382656 +  12q23.3   [Description]    (hg19-Feb_2009)
EnsemblTDG - 12q23.3 [CytoView]
Mapping of homologs : NCBITDG [Mapview]
OMIM601423   
Gene and transcription
Genbank (Entrez)AI004247 AI452763 AK295387 AK299832 AK303631
RefSeq transcript (SRS)NM_001008411 NM_003211
RefSeq transcript (Entrez)NM_001008411 NM_003211
RefSeq genomic (SRS)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838061 NW_004078075
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838061 NW_004078075
Consensus coding sequences : CCDS (NCBI)TDG
Cluster EST : UnigeneHs.584809 [ SRS ] Hs.584809 [ NCBI ]
CGAP (NCI)Hs.584809
Alternative Splicing : Fast-db (Paris)GSHG0006951
Alternative Splicing GalleryENSG00000139372
Gene ExpressionTDG [ NCBI-GEO ]   TDG [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13569 (SRS) Q13569 (Uniprot)
NextProtQ13569
With graphics : InterProQ13569
Splice isoforms : SwissVarQ13569(Swissvar)
Domains : Interpro (SRS)DNA_glycosylase_G/T-mismatch    Thymine-DNA_glycosylase    Uracil-DNA_glycosylase-like   
Domains : Interpro (EBI)DNA_glycosylase_G/T-mismatch    Thymine-DNA_glycosylase    Uracil-DNA_glycosylase-like   
Related proteins : CluSTrQ13569
Domain families : Pfam (SRS)UDG (PF03167)   
Domain families : Pfam (Sanger)UDG (PF03167)   
Domain families : Pfam (NCBI)pfam03167   
Domain families : Smart (EMBL)UDG (SM00986)  
DMDM6996
Blocks (Seattle)Q13569
PDB (SRS)1WYW    2D07    2RBA    3UFJ    3UO7    3UOB    4FNC   
PDB (PDBSum)1WYW    2D07    2RBA    3UFJ    3UO7    3UOB    4FNC   
PDB (IMB)1WYW    2D07    2RBA    3UFJ    3UO7    3UOB    4FNC   
PDB (RSDB)1WYW    2D07    2RBA    3UFJ    3UO7    3UOB    4FNC   
Human Protein AtlasENSG00000139372
HPRD03251
IPIIPI00333201   IPI00909580   IPI00909826   IPI00976977   IPI01011249   IPI01009111   IPI01011228   IPI01015010   IPI01014539   
Protein Interaction databases
DIP (DOE-UCLA)Q13569
IntAct (EBI)Q13569
FunCoupENSG00000139372
REACTOMETDG
Protein Interaction Database6996
BioGRIDTDG
InParanoidQ13569
Interologous Interaction database Q13569
IntegromeDBTDG
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TDG
SNP (GeneSNP Utah)TDG
SNP : HGBaseTDG
Genetic variants : HAPMAPTDG
Somatic Mutations in Cancer : COSMICTDG 
CONAN: Copy Number AnalysisTDG 
Mutations and Diseases : HGMDTDG
OMIM601423   
GENETests601423   
Disease Genetic AssociationTDG
Huge Navigator TDG [HugePedia]  TDG [HugeCancerGEM]
Genomic VariantsTDG  TDG [DGVbeta]
snp3D : Map Gene to Disease6996
General knowledge
Homologs : HomoloGeneTDG
Homology/Alignments : Family Browser (UCSC)TDG
Phylogenetic Trees/Animal Genes : TreeFamTDG
Catalytic activity : Enzyme3.2.2.29 [ Enzyme-Expasy ]   3.2.2.29 [ Enzyme-SRS ]   3.2.2.29 [ IntEnz-EBI ]   3.2.2.29 [ BRENDA ]   3.2.2.29 [ KEGG ]   
Chemical/Protein Interactions : CTD6996
Chemical/Pharm GKB GenePA36419
Clinical trialTDG
Cancer Resource (Charite)ENSG00000139372
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription cofactor activity  damaged DNA binding  protein binding  nucleoplasm  DNA repair  base-excision repair  base-excision repair, AP site formation  mismatch repair  pyrimidine-specific mismatch base pair DNA N-glycosylase activity  PML body  mismatched DNA binding  negative regulation of protein binding  SUMO binding  negative regulation of chromatin binding  depyrimidination  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription cofactor activity  damaged DNA binding  protein binding  nucleoplasm  DNA repair  base-excision repair  base-excision repair, AP site formation  mismatch repair  pyrimidine-specific mismatch base pair DNA N-glycosylase activity  PML body  mismatched DNA binding  negative regulation of protein binding  SUMO binding  negative regulation of chromatin binding  depyrimidination  
Other databases
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
PubGeneTDG
iHOPTDG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:47:44 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.