TDRKH (tudor and KH domain containing)

2014-11-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
TDRD2
FUSION GENES

Other Information

Locus ID:

NCBI: 11022
MIM: 609501
HGNC: 11713
Ensembl: ENSG00000182134

Variants:

dbSNP: 11022
ClinVar: 11022
TCGA: ENSG00000182134
COSMIC: TDRKH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182134ENST00000368822Q9Y2W6
ENSG00000182134ENST00000368823Q5SZR4
ENSG00000182134ENST00000368824Q9Y2W6
ENSG00000182134ENST00000368825Q9Y2W6
ENSG00000182134ENST00000368827Q9Y2W6
ENSG00000182134ENST00000440583F6TB26
ENSG00000182134ENST00000458431Q9Y2W6
ENSG00000182134ENST00000525790B7ZAG4
ENSG00000182134ENST00000526378E9PKN8
ENSG00000182134ENST00000526413B7ZAG4
ENSG00000182134ENST00000530202E9PQX4

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Gene Silencing by RNAREACTOMER-HSA-211000
PIWI-interacting RNA (piRNA) biogenesisREACTOMER-HSA-5601884

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
159558132005Tudor domains bind symmetrical dimethylated arginines.96
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
291181432017Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.6
305038562019TDRKH is a candidate gene for an autosomal dominant distal hereditary motor neuropathy.0

Citation

Dessen P

TDRKH (tudor and KH domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74605/tdrkh