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TEAD1 (TEA domain transcription factor 1)

Identity

Alias_namesTCF13
AA
atrophia areata, peripapillary chorioretinal degeneration
TEA domain family member 1 (SV40 transcriptional enhancer factor)
Alias_symbol (synonym)TEF-1
Other aliasNTEF-1
REF1
TCF-13
TEAD-1
HGNC (Hugo) TEAD1
LocusID (NCBI) 7003
Atlas_Id 50607
Location 11p15.3  [Link to chromosome band 11p15]
Location_base_pair Starts at 12674422 and ends at 12944737 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARNTL (11p15.2) / TEAD1 (11p15.3)ATP5L (11q23.3) / TEAD1 (11p15.3)C9 (5p13.1) / TEAD1 (11p15.3)
CLPTM1L (5p15.33) / TEAD1 (11p15.3)PARVA (11p15.3) / TEAD1 (11p15.3)PIK3C2A (11p15.1) / TEAD1 (11p15.3)
SEMA6A (5q23.1) / TEAD1 (11p15.3)TEAD1 (11p15.3) / ABCC8 (11p15.1)TEAD1 (11p15.3) / ATP5L (11q23.3)
TEAD1 (11p15.3) / CAP2 (6p22.3)TEAD1 (11p15.3) / MICAL2 (11p15.3)TEAD1 (11p15.3) / NCOA2 (8q13.3)
TEAD1 (11p15.3) / PARVA (11p15.3)TEAD1 (11p15.3) / TEAD1 (11p15.3)TEAD1 (11p15.3) / WDR41 (5q13.3)
UBAP2 (9p13.3) / TEAD1 (11p15.3)ARNTL 11p15.2 / TEAD1 11p15.3TEAD1 11p15.3 / CAP2 6p22.3
TEAD1 11p15.3 / MICAL2 11p15.3TEAD1 11p15.3 / PARVA 11p15.3UBAP2 9p13.3 / TEAD1 11p15.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 13 ]

Solid Tumors ProstateOverviewID5041 rhabID5004 softissuTumID5042 TranslocLungSmallCellCarcID6651 TT_del11p15p15ID6571
TT_t0511p15p15ID106492 TT_t0611p22p15ID106871 TT_t0811q13p15ID6614 TT_t0911p13p15ID108278 TT_t1111p15p15ID100510
TT_t1111p15p15ID100555 TT_t1111p15p15ID100556 TT_t1111p15q23ID6721

External links

Nomenclature
HGNC (Hugo)TEAD1   11714
Cards
Entrez_Gene (NCBI)TEAD1  7003  TEA domain transcription factor 1
AliasesAA; NTEF-1; REF1; TCF-13; 
TCF13; TEAD-1; TEF-1
GeneCards (Weizmann)TEAD1
Ensembl hg19 (Hinxton)ENSG00000187079 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187079 [Gene_View]  ENSG00000187079 [Sequence]  chr11:12674422-12944737 [Contig_View]  TEAD1 [Vega]
ICGC DataPortalENSG00000187079
TCGA cBioPortalTEAD1
AceView (NCBI)TEAD1
Genatlas (Paris)TEAD1
WikiGenes7003
SOURCE (Princeton)TEAD1
Genetics Home Reference (NIH)TEAD1
Genomic and cartography
GoldenPath hg38 (UCSC)TEAD1  -     chr11:12674422-12944737 +  11p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TEAD1  -     11p15.3   [Description]    (hg19-Feb_2009)
GoldenPathTEAD1 - 11p15.3 [CytoView hg19]  TEAD1 - 11p15.3 [CytoView hg38]
ImmunoBaseENSG00000187079
Mapping of homologs : NCBITEAD1 [Mapview hg19]  TEAD1 [Mapview hg38]
OMIM108985   189967   
Gene and transcription
Genbank (Entrez)AB209858 AI189919 AI199443 AK027342 AK075070
RefSeq transcript (Entrez)NM_021961
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TEAD1
Alternative Splicing GalleryENSG00000187079
Gene ExpressionTEAD1 [ NCBI-GEO ]   TEAD1 [ EBI - ARRAY_EXPRESS ]   TEAD1 [ SEEK ]   TEAD1 [ MEM ]
Gene Expression Viewer (FireBrowse)TEAD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)7003
GTEX Portal (Tissue expression)TEAD1
Human Protein AtlasENSG00000187079-TEAD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TEAD1
DMDM Disease mutations7003
Blocks (Seattle)TEAD1
Human Protein Atlas [tissue]ENSG00000187079-TEAD1 [tissue]
HPRD01802
IPIIPI00002901   IPI00844019   IPI00978120   IPI00980149   
Protein Interaction databases
FunCoupENSG00000187079
BioGRIDTEAD1
STRING (EMBL)TEAD1
ZODIACTEAD1
Ontologies - Pathways
Huge Navigator TEAD1 [HugePedia]
snp3D : Map Gene to Disease7003
BioCentury BCIQTEAD1
ClinGenTEAD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7003
Chemical/Pharm GKB GenePA36432
Clinical trialTEAD1
Miscellaneous
canSAR (ICR)TEAD1 (select the gene name)
DataMed IndexTEAD1
Probes
Litterature
PubMed95 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTEAD1
EVEXTEAD1
GoPubMedTEAD1
iHOPTEAD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 19 17:12:32 CET 2020
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