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TECR (trans-2,3-enoyl-CoA reductase)

Identity

Alias_namesSC2
GPSN2
glycoprotein
Alias_symbol (synonym)TER
MRT14
Other alias
HGNC (Hugo) TECR
LocusID (NCBI) 9524
Atlas_Id 54061
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 14529560 and ends at 14565980 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
OSBPL5 (11p15.4) / TECR (19p13.12)STRN4 (19q13.32) / TECR (19p13.12)TECR (19p13.12) / PKN1 (19p13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Prostate tumors: an overview


External links

Nomenclature
HGNC (Hugo)TECR   4551
Cards
Entrez_Gene (NCBI)TECR  9524  trans-2,3-enoyl-CoA reductase
AliasesGPSN2; MRT14; SC2; TER
GeneCards (Weizmann)TECR
Ensembl hg19 (Hinxton)ENSG00000099797 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099797 [Gene_View]  chr19:14529560-14565980 [Contig_View]  TECR [Vega]
ICGC DataPortalENSG00000099797
TCGA cBioPortalTECR
AceView (NCBI)TECR
Genatlas (Paris)TECR
WikiGenes9524
SOURCE (Princeton)TECR
Genetics Home Reference (NIH)TECR
Genomic and cartography
GoldenPath hg38 (UCSC)TECR  -     chr19:14529560-14565980 +  19p13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TECR  -     19p13.12   [Description]    (hg19-Feb_2009)
EnsemblTECR - 19p13.12 [CytoView hg19]  TECR - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBITECR [Mapview hg19]  TECR [Mapview hg38]
OMIM610057   614020   
Gene and transcription
Genbank (Entrez)AF038958 AF038959 AF222742 AK001416 AK094087
RefSeq transcript (Entrez)NM_001321170 NM_004868 NM_138501
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TECR
Cluster EST : UnigeneHs.515642 [ NCBI ]
CGAP (NCI)Hs.515642
Alternative Splicing GalleryENSG00000099797
Gene ExpressionTECR [ NCBI-GEO ]   TECR [ EBI - ARRAY_EXPRESS ]   TECR [ SEEK ]   TECR [ MEM ]
Gene Expression Viewer (FireBrowse)TECR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9524
GTEX Portal (Tissue expression)TECR
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZ01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZ01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZ01
Splice isoforms : SwissVarQ9NZ01
PhosPhoSitePlusQ9NZ01
Domaine pattern : Prosite (Expaxy)S5A_REDUCTASE (PS50244)   
Domains : Interpro (EBI)3-oxo-5_a-steroid_4-DH_C    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)Steroid_dh (PF02544)   
Domain families : Pfam (NCBI)pfam02544   
Conserved Domain (NCBI)TECR
DMDM Disease mutations9524
Blocks (Seattle)TECR
PDB (SRS)2DZJ   
PDB (PDBSum)2DZJ   
PDB (IMB)2DZJ   
PDB (RSDB)2DZJ   
Structural Biology KnowledgeBase2DZJ   
SCOP (Structural Classification of Proteins)2DZJ   
CATH (Classification of proteins structures)2DZJ   
SuperfamilyQ9NZ01
Human Protein AtlasENSG00000099797
Peptide AtlasQ9NZ01
HPRD17076
IPIIPI00100656   IPI00301279   IPI00644037   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZ01
IntAct (EBI)Q9NZ01
FunCoupENSG00000099797
BioGRIDTECR
STRING (EMBL)TECR
ZODIACTECR
Ontologies - Pathways
QuickGOQ9NZ01
Ontology : AmiGOprotein binding  nucleus  endoplasmic reticulum  endoplasmic reticulum membrane  oxidoreductase activity  very-long-chain-acyl-CoA dehydrogenase activity  integral component of endoplasmic reticulum membrane  fatty acid elongation  long-chain fatty-acyl-CoA biosynthetic process  very long-chain fatty acid biosynthetic process  oxidation-reduction process  
Ontology : EGO-EBIprotein binding  nucleus  endoplasmic reticulum  endoplasmic reticulum membrane  oxidoreductase activity  very-long-chain-acyl-CoA dehydrogenase activity  integral component of endoplasmic reticulum membrane  fatty acid elongation  long-chain fatty-acyl-CoA biosynthetic process  very long-chain fatty acid biosynthetic process  oxidation-reduction process  
Pathways : KEGGFatty acid elongation    Biosynthesis of unsaturated fatty acids   
NDEx NetworkTECR
Atlas of Cancer Signalling NetworkTECR
Wikipedia pathwaysTECR
Orthology - Evolution
OrthoDB9524
GeneTree (enSembl)ENSG00000099797
Phylogenetic Trees/Animal Genes : TreeFamTECR
HOVERGENQ9NZ01
HOGENOMQ9NZ01
Homologs : HomoloGeneTECR
Homology/Alignments : Family Browser (UCSC)TECR
Gene fusions - Rearrangements
Fusion : MitelmanSTRN4/TECR [19q13.32/19p13.12]  [t(19;19)(p13;q13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTECR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TECR
dbVarTECR
ClinVarTECR
1000_GenomesTECR 
Exome Variant ServerTECR
ExAC (Exome Aggregation Consortium)TECR (select the gene name)
Genetic variants : HAPMAP9524
Genomic Variants (DGV)TECR [DGVbeta]
DECIPHERTECR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTECR 
Mutations
ICGC Data PortalTECR 
TCGA Data PortalTECR 
Broad Tumor PortalTECR
OASIS PortalTECR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTECR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTECR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TECR
DgiDB (Drug Gene Interaction Database)TECR
DoCM (Curated mutations)TECR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TECR (select a term)
intoGenTECR
Cancer3DTECR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610057    614020   
Orphanet11804   
MedgenTECR
Genetic Testing Registry TECR
NextProtQ9NZ01 [Medical]
TSGene9524
GENETestsTECR
Target ValidationTECR
Huge Navigator TECR [HugePedia]
snp3D : Map Gene to Disease9524
BioCentury BCIQTECR
ClinGenTECR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9524
Chemical/Pharm GKB GenePA28946
Clinical trialTECR
Miscellaneous
canSAR (ICR)TECR (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTECR
EVEXTECR
GoPubMedTECR
iHOPTECR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:59:01 CEST 2017

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