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TECTA (tectorin alpha)

Identity

Alias_namesDFNA12
DFNA8
DFNB21
Other alias
HGNC (Hugo) TECTA
LocusID (NCBI) 7007
Atlas_Id 53676
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 120973375 and ends at 121061515 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DIP2C (10p15.3) / TECTA (11q23.3)PATL1 (11q12.1) / TECTA (11q23.3)RAB34 (17q11.2) / TECTA (11q23.3)
RAB39A (11q22.3) / TECTA (11q23.3)SORL1 (11q24.1) / TECTA (11q23.3)TBCEL (11q23.3) / TECTA (11q23.3)
TECTA (11q23.3) / TBCEL (11q23.3)TMEM25 (11q23.3) / TECTA (11q23.3)TECTA 11q23.3 / TBCEL 11q23.3
DIP2C 10p15.3 / TECTA 11q23.3PATL1 11q12.1 / TECTA 11q23.3RAB39 TECTA 11q23.3
SORL1 11q24.1 / TECTA 11q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TECTA   11720
Cards
Entrez_Gene (NCBI)TECTA  7007  tectorin alpha
AliasesDFNA12; DFNA8; DFNB21
GeneCards (Weizmann)TECTA
Ensembl hg19 (Hinxton)ENSG00000109927 [Gene_View]  chr11:120973375-121061515 [Contig_View]  TECTA [Vega]
Ensembl hg38 (Hinxton)ENSG00000109927 [Gene_View]  chr11:120973375-121061515 [Contig_View]  TECTA [Vega]
ICGC DataPortalENSG00000109927
TCGA cBioPortalTECTA
AceView (NCBI)TECTA
Genatlas (Paris)TECTA
WikiGenes7007
SOURCE (Princeton)TECTA
Genetics Home Reference (NIH)TECTA
Genomic and cartography
GoldenPath hg19 (UCSC)TECTA  -     chr11:120973375-121061515 +  11q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TECTA  -     11q23.3   [Description]    (hg38-Dec_2013)
EnsemblTECTA - 11q23.3 [CytoView hg19]  TECTA - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBITECTA [Mapview hg19]  TECTA [Mapview hg38]
OMIM601543   602574   603629   
Gene and transcription
Genbank (Entrez)AF143331 BC156465 BC172509
RefSeq transcript (Entrez)NM_005422
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_011633 NT_033899 NW_004929381
Consensus coding sequences : CCDS (NCBI)TECTA
Cluster EST : UnigeneHs.248162 [ NCBI ]
CGAP (NCI)Hs.248162
Alternative Splicing GalleryENSG00000109927
Gene ExpressionTECTA [ NCBI-GEO ]   TECTA [ EBI - ARRAY_EXPRESS ]   TECTA [ SEEK ]   TECTA [ MEM ]
Gene Expression Viewer (FireBrowse)TECTA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7007
GTEX Portal (Tissue expression)TECTA
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75443   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75443  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75443
Splice isoforms : SwissVarO75443
PhosPhoSitePlusO75443
Domaine pattern : Prosite (Expaxy)NIDO (PS51220)    VWFD (PS51233)    ZP_1 (PS00682)    ZP_2 (PS51034)   
Domains : Interpro (EBI)EGF-like_dom    NIDO_dom    TECTA    TIL_dom    TILa_dom    Unchr_dom_Cys-rich    VWC_out    VWF_dom    VWF_type-D    ZP_dom    ZP_dom_CS   
Domain families : Pfam (Sanger)C8 (PF08742)    NIDO (PF06119)    TIL (PF01826)    TILa (PF12714)    VWD (PF00094)    Zona_pellucida (PF00100)   
Domain families : Pfam (NCBI)pfam08742    pfam06119    pfam01826    pfam12714    pfam00094    pfam00100   
Domain families : Smart (EMBL)C8 (SM00832)  EGF (SM00181)  NIDO (SM00539)  VWC (SM00214)  VWC_out (SM00215)  VWD (SM00216)  ZP (SM00241)  
Conserved Domain (NCBI)TECTA
DMDM Disease mutations7007
Blocks (Seattle)TECTA
SuperfamilyO75443
Human Protein AtlasENSG00000109927
Peptide AtlasO75443
HPRD03985
IPIIPI00023051   
Protein Interaction databases
DIP (DOE-UCLA)O75443
IntAct (EBI)O75443
FunCoupENSG00000109927
BioGRIDTECTA
STRING (EMBL)TECTA
ZODIACTECTA
Ontologies - Pathways
QuickGOO75443
Ontology : AmiGOextracellular matrix structural constituent  proteinaceous extracellular matrix  plasma membrane  cell-matrix adhesion  sensory perception of sound  anchored component of membrane  extracellular exosome  
Ontology : EGO-EBIextracellular matrix structural constituent  proteinaceous extracellular matrix  plasma membrane  cell-matrix adhesion  sensory perception of sound  anchored component of membrane  extracellular exosome  
NDEx NetworkTECTA
Atlas of Cancer Signalling NetworkTECTA
Wikipedia pathwaysTECTA
Orthology - Evolution
OrthoDB7007
GeneTree (enSembl)ENSG00000109927
Phylogenetic Trees/Animal Genes : TreeFamTECTA
HOVERGENO75443
HOGENOMO75443
Homologs : HomoloGeneTECTA
Homology/Alignments : Family Browser (UCSC)TECTA
Gene fusions - Rearrangements
Fusion : MitelmanDIP2C/TECTA [10p15.3/11q23.3]  [t(10;11)(p15;q23)]  
Fusion : MitelmanPATL1/TECTA [11q12.1/11q23.3]  [t(11;11)(q12;q23)]  
Fusion : MitelmanRAB39A/TECTA [11q22.3/11q23.3]  [t(11;11)(q22;q23)]  
Fusion : MitelmanSORL1/TECTA [11q24.1/11q23.3]  [t(11;11)(q23;q24)]  
Fusion: TCGADIP2C 10p15.3 TECTA 11q23.3 HNSC
Fusion: TCGAPATL1 11q12.1 TECTA 11q23.3 GBM
Fusion: TCGARAB39 TECTA 11q23.3 LUAD
Fusion: TCGASORL1 11q24.1 TECTA 11q23.3 BRCA OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTECTA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TECTA
dbVarTECTA
ClinVarTECTA
1000_GenomesTECTA 
Exome Variant ServerTECTA
ExAC (Exome Aggregation Consortium)TECTA (select the gene name)
Genetic variants : HAPMAP7007
Genomic Variants (DGV)TECTA [DGVbeta]
DECIPHER (Syndromes)11:120973375-121061515  ENSG00000109927
CONAN: Copy Number AnalysisTECTA 
Mutations
ICGC Data PortalTECTA 
TCGA Data PortalTECTA 
Broad Tumor PortalTECTA
OASIS PortalTECTA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTECTA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTECTA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Retinal and hearing impairment genetic mutation database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TECTA
DgiDB (Drug Gene Interaction Database)TECTA
DoCM (Curated mutations)TECTA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TECTA (select a term)
intoGenTECTA
Cancer3DTECTA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601543    602574    603629   
Orphanet12046    12047   
MedgenTECTA
Genetic Testing Registry TECTA
NextProtO75443 [Medical]
TSGene7007
GENETestsTECTA
Huge Navigator TECTA [HugePedia]
snp3D : Map Gene to Disease7007
BioCentury BCIQTECTA
ClinGenTECTA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7007
Chemical/Pharm GKB GenePA36437
Clinical trialTECTA
Miscellaneous
canSAR (ICR)TECTA (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTECTA
EVEXTECTA
GoPubMedTECTA
iHOPTECTA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:30:46 CET 2017

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