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TEN1 (TEN1 subunit of CST complex)

Identity

Alias (NCBI)C17orf106
HGNC (Hugo) TEN1
HGNC Alias symbFLJ39785
HGNC Previous nameC17orf106
HGNC Previous namechromosome 17 open reading frame 106
 TEN1 telomerase capping complex subunit homolog (S. cerevisiae)
 TEN1 CST complex subunit
 TEN1, CST complex subunit
LocusID (NCBI) 100134934
Atlas_Id 57843
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 75979240 and ends at 76000586 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TEN1 (17q25.1) / CDK3 (17q25.1)TEN1 (17q25.1) / UNK (17q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TEN1   37242
Cards
Entrez_Gene (NCBI)TEN1    TEN1 subunit of CST complex
AliasesC17orf106
GeneCards (Weizmann)TEN1
Ensembl hg19 (Hinxton)ENSG00000257949 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000257949 [Gene_View]  ENSG00000257949 [Sequence]  chr17:75979240-76000586 [Contig_View]  TEN1 [Vega]
ICGC DataPortalENSG00000257949
TCGA cBioPortalTEN1
AceView (NCBI)TEN1
Genatlas (Paris)TEN1
SOURCE (Princeton)TEN1
Genetics Home Reference (NIH)TEN1
Genomic and cartography
GoldenPath hg38 (UCSC)TEN1  -     chr17:75979240-76000586 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TEN1  -     17q25.1   [Description]    (hg19-Feb_2009)
GoldenPathTEN1 - 17q25.1 [CytoView hg19]  TEN1 - 17q25.1 [CytoView hg38]
ImmunoBaseENSG00000257949
Genome Data Viewer NCBITEN1 [Mapview hg19]  
OMIM613130   
Gene and transcription
Genbank (Entrez)BC047782 BX648576 DB216497 FJ790671
RefSeq transcript (Entrez)NM_001113324
Consensus coding sequences : CCDS (NCBI)TEN1
Gene ExpressionTEN1 [ NCBI-GEO ]   TEN1 [ EBI - ARRAY_EXPRESS ]   TEN1 [ SEEK ]   TEN1 [ MEM ]
Gene Expression Viewer (FireBrowse)TEN1 [ Firebrowse - Broad ]
GenevisibleExpression of TEN1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100134934
GTEX Portal (Tissue expression)TEN1
Human Protein AtlasENSG00000257949-TEN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86WV5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86WV5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86WV5
PhosPhoSitePlusQ86WV5
Domains : Interpro (EBI)Ten1_animal_plant   
Domain families : Pfam (Sanger)Ten1_2 (PF15490)   
Domain families : Pfam (NCBI)pfam15490   
Conserved Domain (NCBI)TEN1
PDB (RSDB)4JOI    6W6W   
PDB Europe4JOI    6W6W   
PDB (PDBSum)4JOI    6W6W   
PDB (IMB)4JOI    6W6W   
Structural Biology KnowledgeBase4JOI    6W6W   
SCOP (Structural Classification of Proteins)4JOI    6W6W   
CATH (Classification of proteins structures)4JOI    6W6W   
SuperfamilyQ86WV5
AlphaFold pdb e-kbQ86WV5   
Human Protein Atlas [tissue]ENSG00000257949-TEN1 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q86WV5
IntAct (EBI)Q86WV5
BioGRIDTEN1
STRING (EMBL)TEN1
ZODIACTEN1
Ontologies - Pathways
QuickGOQ86WV5
Ontology : AmiGOchromosome, telomeric region  single-stranded DNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  telomerase inhibitor activity  telomere capping  telomere maintenance via semi-conservative replication  negative regulation of telomere maintenance via telomerase  negative regulation of telomere maintenance via telomerase  telomeric DNA binding  telomeric DNA binding  negative regulation of telomerase activity  CST complex  CST complex  CST complex  
Ontology : EGO-EBIchromosome, telomeric region  single-stranded DNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  telomerase inhibitor activity  telomere capping  telomere maintenance via semi-conservative replication  negative regulation of telomere maintenance via telomerase  negative regulation of telomere maintenance via telomerase  telomeric DNA binding  telomeric DNA binding  negative regulation of telomerase activity  CST complex  CST complex  CST complex  
NDEx NetworkTEN1
Atlas of Cancer Signalling NetworkTEN1
Wikipedia pathwaysTEN1
Orthology - Evolution
OrthoDB100134934
GeneTree (enSembl)ENSG00000257949
Phylogenetic Trees/Animal Genes : TreeFamTEN1
Homologs : HomoloGeneTEN1
Homology/Alignments : Family Browser (UCSC)TEN1
Gene fusions - Rearrangements
Fusion : QuiverTEN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTEN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TEN1
dbVarTEN1
ClinVarTEN1
MonarchTEN1
1000_GenomesTEN1 
Exome Variant ServerTEN1
GNOMAD BrowserENSG00000257949
Varsome BrowserTEN1
ACMGTEN1 variants
VarityQ86WV5
Genomic Variants (DGV)TEN1 [DGVbeta]
DECIPHERTEN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTEN1 
Mutations
ICGC Data PortalTEN1 
TCGA Data PortalTEN1 
Broad Tumor PortalTEN1
OASIS PortalTEN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTEN1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTEN1
Mutations and Diseases : HGMDTEN1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTEN1
DgiDB (Drug Gene Interaction Database)TEN1
DoCM (Curated mutations)TEN1
CIViC (Clinical Interpretations of Variants in Cancer)TEN1
Cancer3DTEN1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613130   
Orphanet
DisGeNETTEN1
MedgenTEN1
Genetic Testing Registry TEN1
NextProtQ86WV5 [Medical]
GENETestsTEN1
Target ValidationTEN1
Huge Navigator TEN1 [HugePedia]
ClinGenTEN1
Clinical trials, drugs, therapy
MyCancerGenomeTEN1
Protein Interactions : CTDTEN1
Pharm GKB GenePA165431550
PharosQ86WV5
Clinical trialTEN1
Miscellaneous
canSAR (ICR)TEN1
HarmonizomeTEN1
DataMed IndexTEN1
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTEN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:44 CEST 2021

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