TENM1 (teneurin transmembrane protein 1)

2016-10-01  

Identity

HGNC
LOCATION
Xq25
LOCUSID
ALIAS
ODZ1,ODZ3,TEN-M1,TEN1,TNM,TNM1,ten-1
FUSION GENES

Other Information

Locus ID:

NCBI: 10178
MIM: 300588
HGNC: 8117
Ensembl: ENSG00000009694

Variants:

dbSNP: 10178
ClinVar: 10178
TCGA: ENSG00000009694
COSMIC: TENM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000009694ENST00000371130Q9UKZ4
ENSG00000009694ENST00000422452Q9UKZ4

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
256667572015Whole-exome sequencing points to considerable genetic heterogeneity of cerebral palsy.31
157777932005The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix.27
270409852016A role for TENM1 mutations in congenital general anosmia.21
251523332014The teneurins: new players in the generation of visual topography.15
276413322017ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA.15
256488962015The intracellular domain of teneurin-1 induces the activity of microphthalmia-associated transcription factor (MITF) by binding to transcriptional repressor HINT1.9
280042212017Overexpression of teneurin transmembrane protein 1 is a potential marker of disease progression in papillary thyroid carcinoma.9
216517642011Human teneurin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter.6
222717002012Skin lesions in a boy with X-linked lymphoproliferative disorder: comparison of 5 SH2D1A deletion cases.4
264857512015Role of the teneurins, teneurin C-terminal associated peptides (TCAP) in reproduction: clinical perspectives.2

Citation

Dessen P

TENM1 (teneurin transmembrane protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56539/tenm1