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TENM1 (teneurin transmembrane protein 1)

Identity

Alias (NCBI)ODZ1
ODZ3
TEN-M1
TEN1
TNM
TNM1
ten-1
HGNC (Hugo) TENM1
HGNC Alias symbTEN-M1
TEN1
HGNC Previous nameODZ3
 TNM
 ODZ1
HGNC Previous nametenascin M
 odz, odd Oz/ten-m homolog 1 (Drosophila)
LocusID (NCBI) 10178
Atlas_Id 56539
Location Xq25  [Link to chromosome band Xq25]
Location_base_pair Starts at 124375906 and ends at 124963817 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BACH1 (21q21.3) / TENM1 (Xq25)C11orf73 (11q14.2) / TENM1 (Xq25)KSR1 (17q11.1) / TENM1 (Xq25)
RPH3AL (17p13.3) / TENM1 (Xq25)TENM1 (Xq25) / TMEM170A (16q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(X;17)(q25;q11) KSR1/TENM1


External links

 

Nomenclature
HGNC (Hugo)TENM1   8117
Cards
Entrez_Gene (NCBI)TENM1    teneurin transmembrane protein 1
AliasesODZ1; ODZ3; TEN-M1; TEN1; 
TNM; TNM1; ten-1
GeneCards (Weizmann)TENM1
Ensembl hg19 (Hinxton)ENSG00000009694 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000009694 [Gene_View]  ENSG00000009694 [Sequence]  chrX:124375906-124963817 [Contig_View]  TENM1 [Vega]
ICGC DataPortalENSG00000009694
TCGA cBioPortalTENM1
AceView (NCBI)TENM1
Genatlas (Paris)TENM1
SOURCE (Princeton)TENM1
Genetics Home Reference (NIH)TENM1
Genomic and cartography
GoldenPath hg38 (UCSC)TENM1  -     chrX:124375906-124963817 -  Xq25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TENM1  -     Xq25   [Description]    (hg19-Feb_2009)
GoldenPathTENM1 - Xq25 [CytoView hg19]  TENM1 - Xq25 [CytoView hg38]
ImmunoBaseENSG00000009694
Genome Data Viewer NCBITENM1 [Mapview hg19]  
OMIM300588   
Gene and transcription
Genbank (Entrez)AF100772 AI498402 AK055765 BC030766 BC140783
RefSeq transcript (Entrez)NM_001163278 NM_001163279 NM_014253
Consensus coding sequences : CCDS (NCBI)TENM1
Gene ExpressionTENM1 [ NCBI-GEO ]   TENM1 [ EBI - ARRAY_EXPRESS ]   TENM1 [ SEEK ]   TENM1 [ MEM ]
Gene Expression Viewer (FireBrowse)TENM1 [ Firebrowse - Broad ]
GenevisibleExpression of TENM1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10178
GTEX Portal (Tissue expression)TENM1
Human Protein AtlasENSG00000009694-TENM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKZ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKZ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKZ4
PhosPhoSitePlusQ9UKZ4
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    TENEURIN_N (PS51361)   
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like    EGF-like_dom    Ten_N    Tox-GHH_dom    YD   
Domain families : Pfam (Sanger)Ten_N (PF06484)    Tox-GHH (PF15636)   
Domain families : Pfam (NCBI)pfam06484    pfam15636   
Domain families : Smart (EMBL)EGF (SM00181)  
Conserved Domain (NCBI)TENM1
SuperfamilyQ9UKZ4
AlphaFold pdb e-kbQ9UKZ4   
Human Protein Atlas [tissue]ENSG00000009694-TENM1 [tissue]
HPRD06669
Protein Interaction databases
DIP (DOE-UCLA)Q9UKZ4
IntAct (EBI)Q9UKZ4
BioGRIDTENM1
STRING (EMBL)TENM1
ZODIACTENM1
Ontologies - Pathways
QuickGOQ9UKZ4
Ontology : AmiGOextracellular region  nucleus  cytoplasm  endoplasmic reticulum  Golgi apparatus  cytoskeleton  plasma membrane  integral component of plasma membrane  regulation of transcription by RNA polymerase III  immune response  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  neuropeptide signaling pathway  nervous system development  heparin binding  negative regulation of cell population proliferation  nuclear matrix  nuclear speck  positive regulation of actin filament polymerization  positive regulation of peptidyl-serine phosphorylation  protein homodimerization activity  protein homodimerization activity  neuron projection  positive regulation of MAP kinase activity  protein heterodimerization activity  protein heterodimerization activity  perinuclear region of cytoplasm  neuron development  cell adhesion molecule binding  positive regulation of filopodium assembly  positive regulation of intracellular protein transport  
Ontology : EGO-EBIextracellular region  nucleus  cytoplasm  endoplasmic reticulum  Golgi apparatus  cytoskeleton  plasma membrane  integral component of plasma membrane  regulation of transcription by RNA polymerase III  immune response  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  neuropeptide signaling pathway  nervous system development  heparin binding  negative regulation of cell population proliferation  nuclear matrix  nuclear speck  positive regulation of actin filament polymerization  positive regulation of peptidyl-serine phosphorylation  protein homodimerization activity  protein homodimerization activity  neuron projection  positive regulation of MAP kinase activity  protein heterodimerization activity  protein heterodimerization activity  perinuclear region of cytoplasm  neuron development  cell adhesion molecule binding  positive regulation of filopodium assembly  positive regulation of intracellular protein transport  
NDEx NetworkTENM1
Atlas of Cancer Signalling NetworkTENM1
Wikipedia pathwaysTENM1
Orthology - Evolution
OrthoDB10178
GeneTree (enSembl)ENSG00000009694
Phylogenetic Trees/Animal Genes : TreeFamTENM1
Homologs : HomoloGeneTENM1
Homology/Alignments : Family Browser (UCSC)TENM1
Gene fusions - Rearrangements
Fusion : QuiverTENM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTENM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TENM1
dbVarTENM1
ClinVarTENM1
MonarchTENM1
1000_GenomesTENM1 
Exome Variant ServerTENM1
GNOMAD BrowserENSG00000009694
Varsome BrowserTENM1
ACMGTENM1 variants
VarityQ9UKZ4
Genomic Variants (DGV)TENM1 [DGVbeta]
DECIPHERTENM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTENM1 
Mutations
ICGC Data PortalTENM1 
TCGA Data PortalTENM1 
Broad Tumor PortalTENM1
OASIS PortalTENM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTENM1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTENM1
Mutations and Diseases : HGMDTENM1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTENM1
DgiDB (Drug Gene Interaction Database)TENM1
DoCM (Curated mutations)TENM1
CIViC (Clinical Interpretations of Variants in Cancer)TENM1
Cancer3DTENM1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300588   
Orphanet
DisGeNETTENM1
MedgenTENM1
Genetic Testing Registry TENM1
NextProtQ9UKZ4 [Medical]
GENETestsTENM1
Target ValidationTENM1
Huge Navigator TENM1 [HugePedia]
ClinGenTENM1
Clinical trials, drugs, therapy
MyCancerGenomeTENM1
Protein Interactions : CTDTENM1
Pharm GKB GenePA31904
PharosQ9UKZ4
Clinical trialTENM1
Miscellaneous
canSAR (ICR)TENM1
HarmonizomeTENM1
DataMed IndexTENM1
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTENM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:34:44 CEST 2021

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