Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TENM1 (teneurin transmembrane protein 1)

Identity

Alias_namesODZ3
TNM
ODZ1
tenascin M
odz, odd Oz/ten-m homolog 1 (Drosophila)
Alias_symbol (synonym)TEN-M1
Other aliasTNM1
HGNC (Hugo) TENM1
LocusID (NCBI) 10178
Atlas_Id 56539
Location Xq25  [Link to chromosome band Xq25]
Location_base_pair Starts at 124375906 and ends at 124963817 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BACH1 (21q21.3) / TENM1 (Xq25)C11orf73 (11q14.2) / TENM1 (Xq25)KSR1 (17q11.1) / TENM1 (Xq25)
RPH3AL (17p13.3) / TENM1 (Xq25)TENM1 (Xq25) / TMEM170A (16q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TENM1   8117
Cards
Entrez_Gene (NCBI)TENM1  10178  teneurin transmembrane protein 1
AliasesODZ1; ODZ3; TEN-M1; TNM; 
TNM1
GeneCards (Weizmann)TENM1
Ensembl hg19 (Hinxton)ENSG00000009694 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000009694 [Gene_View]  chrX:124375906-124963817 [Contig_View]  TENM1 [Vega]
ICGC DataPortalENSG00000009694
TCGA cBioPortalTENM1
AceView (NCBI)TENM1
Genatlas (Paris)TENM1
WikiGenes10178
SOURCE (Princeton)TENM1
Genetics Home Reference (NIH)TENM1
Genomic and cartography
GoldenPath hg38 (UCSC)TENM1  -     chrX:124375906-124963817 -  Xq25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TENM1  -     Xq25   [Description]    (hg19-Feb_2009)
EnsemblTENM1 - Xq25 [CytoView hg19]  TENM1 - Xq25 [CytoView hg38]
Mapping of homologs : NCBITENM1 [Mapview hg19]  TENM1 [Mapview hg38]
OMIM300588   
Gene and transcription
Genbank (Entrez)AF100772 AI498402 AK055765 BC030766 BC140783
RefSeq transcript (Entrez)NM_001163278 NM_001163279 NM_014253
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TENM1
Cluster EST : UnigeneHs.744536 [ NCBI ]
CGAP (NCI)Hs.744536
Alternative Splicing GalleryENSG00000009694
Gene ExpressionTENM1 [ NCBI-GEO ]   TENM1 [ EBI - ARRAY_EXPRESS ]   TENM1 [ SEEK ]   TENM1 [ MEM ]
Gene Expression Viewer (FireBrowse)TENM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10178
GTEX Portal (Tissue expression)TENM1
Human Protein AtlasENSG00000009694-TENM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKZ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKZ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKZ4
Splice isoforms : SwissVarQ9UKZ4
PhosPhoSitePlusQ9UKZ4
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    TENEURIN_N (PS51361)   
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like    EGF-like_CS    EGF-like_dom    Ten_N    TENM1    Tox-GHH_dom    YD   
Domain families : Pfam (Sanger)Ten_N (PF06484)    Tox-GHH (PF15636)   
Domain families : Pfam (NCBI)pfam06484    pfam15636   
Domain families : Smart (EMBL)EGF (SM00181)  
Conserved Domain (NCBI)TENM1
DMDM Disease mutations10178
Blocks (Seattle)TENM1
SuperfamilyQ9UKZ4
Human Protein Atlas [tissue]ENSG00000009694-TENM1 [tissue]
Peptide AtlasQ9UKZ4
HPRD06669
IPIIPI00942033   IPI00003391   IPI00943627   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKZ4
IntAct (EBI)Q9UKZ4
FunCoupENSG00000009694
BioGRIDTENM1
STRING (EMBL)TENM1
ZODIACTENM1
Ontologies - Pathways
QuickGOQ9UKZ4
Ontology : AmiGOextracellular region  nucleus  cytoplasm  endoplasmic reticulum  Golgi apparatus  cytoskeleton  plasma membrane  integral component of plasma membrane  transcription, DNA-templated  regulation of transcription from RNA polymerase III promoter  immune response  neuropeptide signaling pathway  nervous system development  heparin binding  negative regulation of cell proliferation  nuclear matrix  nuclear speck  positive regulation of actin filament polymerization  positive regulation of peptidyl-serine phosphorylation  protein homodimerization activity  positive regulation of MAP kinase activity  protein heterodimerization activity  perinuclear region of cytoplasm  positive regulation of filopodium assembly  positive regulation of intracellular protein transport  
Ontology : EGO-EBIextracellular region  nucleus  cytoplasm  endoplasmic reticulum  Golgi apparatus  cytoskeleton  plasma membrane  integral component of plasma membrane  transcription, DNA-templated  regulation of transcription from RNA polymerase III promoter  immune response  neuropeptide signaling pathway  nervous system development  heparin binding  negative regulation of cell proliferation  nuclear matrix  nuclear speck  positive regulation of actin filament polymerization  positive regulation of peptidyl-serine phosphorylation  protein homodimerization activity  positive regulation of MAP kinase activity  protein heterodimerization activity  perinuclear region of cytoplasm  positive regulation of filopodium assembly  positive regulation of intracellular protein transport  
NDEx NetworkTENM1
Atlas of Cancer Signalling NetworkTENM1
Wikipedia pathwaysTENM1
Orthology - Evolution
OrthoDB10178
GeneTree (enSembl)ENSG00000009694
Phylogenetic Trees/Animal Genes : TreeFamTENM1
HOVERGENQ9UKZ4
HOGENOMQ9UKZ4
Homologs : HomoloGeneTENM1
Homology/Alignments : Family Browser (UCSC)TENM1
Gene fusions - Rearrangements
Tumor Fusion PortalTENM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTENM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TENM1
dbVarTENM1
ClinVarTENM1
1000_GenomesTENM1 
Exome Variant ServerTENM1
ExAC (Exome Aggregation Consortium)ENSG00000009694
GNOMAD BrowserENSG00000009694
Genetic variants : HAPMAP10178
Genomic Variants (DGV)TENM1 [DGVbeta]
DECIPHERTENM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTENM1 
Mutations
ICGC Data PortalTENM1 
TCGA Data PortalTENM1 
Broad Tumor PortalTENM1
OASIS PortalTENM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTENM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTENM1
BioMutasearch TENM1
DgiDB (Drug Gene Interaction Database)TENM1
DoCM (Curated mutations)TENM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TENM1 (select a term)
intoGenTENM1
Cancer3DTENM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300588   
Orphanet
DisGeNETTENM1
MedgenTENM1
Genetic Testing Registry TENM1
NextProtQ9UKZ4 [Medical]
TSGene10178
GENETestsTENM1
Target ValidationTENM1
Huge Navigator TENM1 [HugePedia]
snp3D : Map Gene to Disease10178
BioCentury BCIQTENM1
ClinGenTENM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10178
Chemical/Pharm GKB GenePA31904
Clinical trialTENM1
Miscellaneous
canSAR (ICR)TENM1 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTENM1
EVEXTENM1
GoPubMedTENM1
iHOPTENM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:38:07 CET 2017

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