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TENM2 (teneurin transmembrane protein 2)

Identity

Alias (NCBI)ODZ2
TEN-M2
TEN2
TNM2
ten-2
HGNC (Hugo) TENM2
HGNC Alias symbKIAA1127
Ten-M2
TEN2
HGNC Previous nameODZ2
HGNC Previous nameodz, odd Oz/ten-m homolog 2 (Drosophila)
LocusID (NCBI) 57451
Atlas_Id 50560
Location 5q34  [Link to chromosome band 5q34]
Location_base_pair Starts at 167573659 and ends at 168264157 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKH (5p15.2) / TENM2 (5q34)IGH (14q32.33) / TENM2 (5q34)IGHG1 (14q32.33) / TENM2 (5q34)
TBC1D9B (5q35.3) / TENM2 (5q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TENM2   29943
Cards
Entrez_Gene (NCBI)TENM2    teneurin transmembrane protein 2
AliasesODZ2; TEN-M2; TEN2; TNM2; 
ten-2
GeneCards (Weizmann)TENM2
Ensembl hg19 (Hinxton)ENSG00000145934 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145934 [Gene_View]  ENSG00000145934 [Sequence]  chr5:167573659-168264157 [Contig_View]  TENM2 [Vega]
ICGC DataPortalENSG00000145934
TCGA cBioPortalTENM2
AceView (NCBI)TENM2
Genatlas (Paris)TENM2
SOURCE (Princeton)TENM2
Genetics Home Reference (NIH)TENM2
Genomic and cartography
GoldenPath hg38 (UCSC)TENM2  -     chr5:167573659-168264157 +  5q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TENM2  -     5q34   [Description]    (hg19-Feb_2009)
GoldenPathTENM2 - 5q34 [CytoView hg19]  TENM2 - 5q34 [CytoView hg38]
ImmunoBaseENSG00000145934
Genome Data Viewer NCBITENM2 [Mapview hg19]  
OMIM610119   
Gene and transcription
Genbank (Entrez)AB032953 AK056053 AK293262 AK302302 AL137500
RefSeq transcript (Entrez)NM_001080428 NM_001122679 NM_001368145 NM_001368146
Consensus coding sequences : CCDS (NCBI)TENM2
Gene ExpressionTENM2 [ NCBI-GEO ]   TENM2 [ EBI - ARRAY_EXPRESS ]   TENM2 [ SEEK ]   TENM2 [ MEM ]
Gene Expression Viewer (FireBrowse)TENM2 [ Firebrowse - Broad ]
GenevisibleExpression of TENM2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57451
GTEX Portal (Tissue expression)TENM2
Human Protein AtlasENSG00000145934-TENM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NT68   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NT68  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NT68
PhosPhoSitePlusQ9NT68
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    TENEURIN_N (PS51361)   
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like    CarboxyPept-like_regulatory    EGF-like_Ca-bd_dom    EGF-like_dom    Quino_amine_DH_bsu    Rhs_assc_core    Ten-2    Ten_N    Tox-GHH_dom    YD   
Domain families : Pfam (Sanger)Ten_N (PF06484)    Tox-GHH (PF15636)   
Domain families : Pfam (NCBI)pfam06484    pfam15636   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
Conserved Domain (NCBI)TENM2
PDB (RSDB)6CMX    6VHH   
PDB Europe6CMX    6VHH   
PDB (PDBSum)6CMX    6VHH   
PDB (IMB)6CMX    6VHH   
Structural Biology KnowledgeBase6CMX    6VHH   
SCOP (Structural Classification of Proteins)6CMX    6VHH   
CATH (Classification of proteins structures)6CMX    6VHH   
SuperfamilyQ9NT68
AlphaFold pdb e-kbQ9NT68   
Human Protein Atlas [tissue]ENSG00000145934-TENM2 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9NT68
IntAct (EBI)Q9NT68
BioGRIDTENM2
STRING (EMBL)TENM2
ZODIACTENM2
Ontologies - Pathways
QuickGOQ9NT68
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  calcium ion binding  nucleus  endoplasmic reticulum  Golgi apparatus  plasma membrane  integral component of plasma membrane  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  signal transduction  PML body  cell junction  filopodium  dendrite  growth cone  protein homodimerization activity  protein homodimerization activity  neuron projection  neuron projection  dendritic spine  synapse  postsynaptic membrane  protein heterodimerization activity  protein heterodimerization activity  neuron development  cell adhesion molecule binding  positive regulation of filopodium assembly  cell-cell adhesion  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  calcium ion binding  nucleus  endoplasmic reticulum  Golgi apparatus  plasma membrane  integral component of plasma membrane  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  signal transduction  PML body  cell junction  filopodium  dendrite  growth cone  protein homodimerization activity  protein homodimerization activity  neuron projection  neuron projection  dendritic spine  synapse  postsynaptic membrane  protein heterodimerization activity  protein heterodimerization activity  neuron development  cell adhesion molecule binding  positive regulation of filopodium assembly  cell-cell adhesion  
NDEx NetworkTENM2
Atlas of Cancer Signalling NetworkTENM2
Wikipedia pathwaysTENM2
Orthology - Evolution
OrthoDB57451
GeneTree (enSembl)ENSG00000145934
Phylogenetic Trees/Animal Genes : TreeFamTENM2
Homologs : HomoloGeneTENM2
Homology/Alignments : Family Browser (UCSC)TENM2
Gene fusions - Rearrangements
Fusion : MitelmanANKH/TENM2 [5p15.2/5q34]  
Fusion : MitelmanIGH/TENM2 [14q32.33/5q34]  
Fusion : MitelmanTBC1D9B/TENM2 [5q35.3/5q34]  
Fusion : QuiverTENM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTENM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TENM2
dbVarTENM2
ClinVarTENM2
MonarchTENM2
1000_GenomesTENM2 
Exome Variant ServerTENM2
GNOMAD BrowserENSG00000145934
Varsome BrowserTENM2
ACMGTENM2 variants
VarityQ9NT68
Genomic Variants (DGV)TENM2 [DGVbeta]
DECIPHERTENM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTENM2 
Mutations
ICGC Data PortalTENM2 
TCGA Data PortalTENM2 
Broad Tumor PortalTENM2
OASIS PortalTENM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTENM2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTENM2
Mutations and Diseases : HGMDTENM2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTENM2
DgiDB (Drug Gene Interaction Database)TENM2
DoCM (Curated mutations)TENM2
CIViC (Clinical Interpretations of Variants in Cancer)TENM2
Cancer3DTENM2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610119   
Orphanet
DisGeNETTENM2
MedgenTENM2
Genetic Testing Registry TENM2
NextProtQ9NT68 [Medical]
GENETestsTENM2
Target ValidationTENM2
Huge Navigator TENM2 [HugePedia]
ClinGenTENM2
Clinical trials, drugs, therapy
MyCancerGenomeTENM2
Protein Interactions : CTDTENM2
Pharm GKB GenePA134909677
PharosQ9NT68
Clinical trialTENM2
Miscellaneous
canSAR (ICR)TENM2
HarmonizomeTENM2
DataMed IndexTENM2
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTENM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:45 CEST 2021

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