Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TENT4B (terminal nucleotidyltransferase 4B)

Identity

Alias_namesPAP associated domain containing 5
Alias_symbol (synonym)TRF4-2
Other aliasPAPD5
TUT3
HGNC (Hugo) TENT4B
LocusID (NCBI) 64282
Atlas_Id 53652
Location 16q12.1  [Link to chromosome band 16q12]
Location_base_pair Starts at 50152918 and ends at 50235308 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)TENT4B   30758
Cards
Entrez_Gene (NCBI)TENT4B  64282  terminal nucleotidyltransferase 4B
AliasesPAPD5; TRF4-2; TUT3
GeneCards (Weizmann)TENT4B
Ensembl hg19 (Hinxton)ENSG00000121274 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121274 [Gene_View]  ENSG00000121274 [Sequence]  chr16:50152918-50235308 [Contig_View]  TENT4B [Vega]
ICGC DataPortalENSG00000121274
TCGA cBioPortalTENT4B
AceView (NCBI)TENT4B
Genatlas (Paris)TENT4B
WikiGenes64282
SOURCE (Princeton)TENT4B
Genetics Home Reference (NIH)TENT4B
Genomic and cartography
GoldenPath hg38 (UCSC)TENT4B  -     chr16:50152918-50235308 +  16q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TENT4B  -     16q12.1   [Description]    (hg19-Feb_2009)
EnsemblTENT4B - 16q12.1 [CytoView hg19]  TENT4B - 16q12.1 [CytoView hg38]
Mapping of homologs : NCBITENT4B [Mapview hg19]  TENT4B [Mapview hg38]
OMIM605540   
Gene and transcription
Genbank (Entrez)AF089897 AK001141 AK097589 AK098806 AK223410
RefSeq transcript (Entrez)NM_001040284 NM_001040285 NM_001365323 NM_001365324 NM_022447
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TENT4B
Cluster EST : UnigeneHs.514342 [ NCBI ]
CGAP (NCI)Hs.514342
Alternative Splicing GalleryENSG00000121274
Gene ExpressionTENT4B [ NCBI-GEO ]   TENT4B [ EBI - ARRAY_EXPRESS ]   TENT4B [ SEEK ]   TENT4B [ MEM ]
Gene Expression Viewer (FireBrowse)TENT4B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64282
GTEX Portal (Tissue expression)TENT4B
Human Protein AtlasENSG00000121274-TENT4B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NDF8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NDF8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NDF8
Splice isoforms : SwissVarQ8NDF8
Catalytic activity : Enzyme2.7.7.19 [ Enzyme-Expasy ]   2.7.7.192.7.7.19 [ IntEnz-EBI ]   2.7.7.19 [ BRENDA ]   2.7.7.19 [ KEGG ]   
PhosPhoSitePlusQ8NDF8
Domains : Interpro (EBI)PAP_assoc    Polymerase_NTP_transf_dom   
Domain families : Pfam (Sanger)NTP_transf_2 (PF01909)    PAP_assoc (PF03828)   
Domain families : Pfam (NCBI)pfam01909    pfam03828   
Conserved Domain (NCBI)TENT4B
DMDM Disease mutations64282
Blocks (Seattle)TENT4B
SuperfamilyQ8NDF8
Human Protein Atlas [tissue]ENSG00000121274-TENT4B [tissue]
Peptide AtlasQ8NDF8
HPRD16119
IPIIPI01011361   IPI00383794   IPI00550722   IPI00940660   IPI00643763   IPI00301922   
Protein Interaction databases
DIP (DOE-UCLA)Q8NDF8
IntAct (EBI)Q8NDF8
FunCoupENSG00000121274
BioGRIDTENT4B
STRING (EMBL)TENT4B
ZODIACTENT4B
Ontologies - Pathways
QuickGOQ8NDF8
Ontology : AmiGODNA binding  RNA binding  DNA-directed DNA polymerase activity  polynucleotide adenylyltransferase activity  polynucleotide adenylyltransferase activity  protein binding  nucleolus  nucleolus  cytoplasm  rRNA processing  mRNA polyadenylation  cell cycle  miRNA catabolic process  TRAMP complex  TRAMP complex  negative regulation of telomere maintenance via telomerase  carbohydrate homeostasis  ncRNA polyadenylation  ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process  metal ion binding  cell division  telomerase RNA binding  histone mRNA catabolic process  histone mRNA catabolic process  snoRNA polyadenylation  snoRNA polyadenylation  DNA biosynthetic process  
Ontology : EGO-EBIDNA binding  RNA binding  DNA-directed DNA polymerase activity  polynucleotide adenylyltransferase activity  polynucleotide adenylyltransferase activity  protein binding  nucleolus  nucleolus  cytoplasm  rRNA processing  mRNA polyadenylation  cell cycle  miRNA catabolic process  TRAMP complex  TRAMP complex  negative regulation of telomere maintenance via telomerase  carbohydrate homeostasis  ncRNA polyadenylation  ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process  metal ion binding  cell division  telomerase RNA binding  histone mRNA catabolic process  histone mRNA catabolic process  snoRNA polyadenylation  snoRNA polyadenylation  DNA biosynthetic process  
NDEx NetworkTENT4B
Atlas of Cancer Signalling NetworkTENT4B
Wikipedia pathwaysTENT4B
Orthology - Evolution
OrthoDB64282
GeneTree (enSembl)ENSG00000121274
Phylogenetic Trees/Animal Genes : TreeFamTENT4B
HOVERGENQ8NDF8
HOGENOMQ8NDF8
Homologs : HomoloGeneTENT4B
Homology/Alignments : Family Browser (UCSC)TENT4B
Gene fusions - Rearrangements
Fusion : QuiverTENT4B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTENT4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TENT4B
dbVarTENT4B
ClinVarTENT4B
1000_GenomesTENT4B 
Exome Variant ServerTENT4B
ExAC (Exome Aggregation Consortium)ENSG00000121274
GNOMAD BrowserENSG00000121274
Varsome BrowserTENT4B
Genetic variants : HAPMAP64282
Genomic Variants (DGV)TENT4B [DGVbeta]
DECIPHERTENT4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTENT4B 
Mutations
ICGC Data PortalTENT4B 
TCGA Data PortalTENT4B 
Broad Tumor PortalTENT4B
OASIS PortalTENT4B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTENT4B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TENT4B
DgiDB (Drug Gene Interaction Database)TENT4B
DoCM (Curated mutations)TENT4B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TENT4B (select a term)
intoGenTENT4B
Cancer3DTENT4B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605540   
Orphanet
DisGeNETTENT4B
MedgenTENT4B
Genetic Testing Registry TENT4B
NextProtQ8NDF8 [Medical]
TSGene64282
GENETestsTENT4B
Target ValidationTENT4B
Huge Navigator TENT4B [HugePedia]
snp3D : Map Gene to Disease64282
BioCentury BCIQTENT4B
ClinGenTENT4B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64282
Chemical/Pharm GKB GenePA134949693
Clinical trialTENT4B
Miscellaneous
canSAR (ICR)TENT4B (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTENT4B
EVEXTENT4B
GoPubMedTENT4B
iHOPTENT4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:44:32 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.