TES (testin LIM domain protein)

2003-02-01  

Identity

HGNC
LOCATION
7q31.2
LOCUSID
ALIAS
TESS,TESS-2
FUSION GENES

Other Information

Locus ID:

NCBI: 26136
MIM: 606085
HGNC: 14620
Ensembl: ENSG00000135269

Variants:

dbSNP: 26136
ClinVar: 26136
TCGA: ENSG00000135269
COSMIC: TES

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135269ENST00000358204Q9UGI8
ENSG00000135269ENST00000358204A4D0U5
ENSG00000135269ENST00000393481Q9UGI8
ENSG00000135269ENST00000393484H7BYK1
ENSG00000135269ENST00000455989F8W7T0
ENSG00000135269ENST00000492891F8WDI4

Expression (GTEx)

0
50
100
150
200
250

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
181589032007Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding.38
266111252015VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module.19
156627272005RNAi knockdown of the focal adhesion protein TES reveals its role in actin stress fibre organisation.17
229578442012Testin is a tumor suppressor and prognostic marker in breast cancer.16
212783832011Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.13
152528542004Extensive analysis of the 7q31 region in human prostate tumors supports TES as the best candidate tumor suppressor gene.12
206268492010Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene.12
221569392012Comparative gene expression analysis between coronary arteries and internal mammary arteries identifies a role for the TES gene in endothelial cell functions relevant to coronary artery disease.12
205732772010Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia.10
192897032009Downregulation of TESTIN and its association with cancer history and a tendency toward poor survival in head and neck squamous cell carcinoma.9

Citation

Dessen P

TES (testin LIM domain protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42524/tes