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TESC (tescalcin)

Identity

Alias_symbol (synonym)TSC
FLJ20607
CHP3
Other alias
HGNC (Hugo) TESC
LocusID (NCBI) 54997
Atlas_Id 55025
Location 12q24.22  [Link to chromosome band 12q24]
Location_base_pair Starts at 117476728 and ends at 117537251 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TESC (12q24.22) / FBXO21 (12q24.22)TESC (12q24.22) / PSMA7 (20q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TESC   26065
Cards
Entrez_Gene (NCBI)TESC  54997  tescalcin
AliasesCHP3; TSC
GeneCards (Weizmann)TESC
Ensembl hg19 (Hinxton)ENSG00000088992 [Gene_View]  chr12:117476728-117537251 [Contig_View]  TESC [Vega]
Ensembl hg38 (Hinxton)ENSG00000088992 [Gene_View]  chr12:117476728-117537251 [Contig_View]  TESC [Vega]
ICGC DataPortalENSG00000088992
TCGA cBioPortalTESC
AceView (NCBI)TESC
Genatlas (Paris)TESC
WikiGenes54997
SOURCE (Princeton)TESC
Genetics Home Reference (NIH)TESC
Genomic and cartography
GoldenPath hg19 (UCSC)TESC  -     chr12:117476728-117537251 -  12q24.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TESC  -     12q24.22   [Description]    (hg38-Dec_2013)
EnsemblTESC - 12q24.22 [CytoView hg19]  TESC - 12q24.22 [CytoView hg38]
Mapping of homologs : NCBITESC [Mapview hg19]  TESC [Mapview hg38]
OMIM611585   
Gene and transcription
Genbank (Entrez)AF443207 AI372964 AI910454 AK000614 BC015221
RefSeq transcript (Entrez)NM_001168325 NM_017899
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929385
Consensus coding sequences : CCDS (NCBI)TESC
Cluster EST : UnigeneHs.525709 [ NCBI ]
CGAP (NCI)Hs.525709
Alternative Splicing GalleryENSG00000088992
Gene ExpressionTESC [ NCBI-GEO ]   TESC [ EBI - ARRAY_EXPRESS ]   TESC [ SEEK ]   TESC [ MEM ]
Gene Expression Viewer (FireBrowse)TESC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54997
GTEX Portal (Tissue expression)TESC
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96BS2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96BS2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96BS2
Splice isoforms : SwissVarQ96BS2
PhosPhoSitePlusQ96BS2
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TESC
DMDM Disease mutations54997
Blocks (Seattle)TESC
SuperfamilyQ96BS2
Human Protein AtlasENSG00000088992
Peptide AtlasQ96BS2
HPRD11649
IPIIPI00791863   IPI01023076   IPI00954908   IPI00793596   IPI00978383   
Protein Interaction databases
DIP (DOE-UCLA)Q96BS2
IntAct (EBI)Q96BS2
FunCoupENSG00000088992
BioGRIDTESC
STRING (EMBL)TESC
ZODIACTESC
Ontologies - Pathways
QuickGOQ96BS2
Ontology : AmiGOmagnesium ion binding  ruffle  protein kinase inhibitor activity  calcium ion binding  protein binding  nucleus  nucleus  cytoplasm  plasma membrane  negative regulation of protein kinase activity  negative regulation of cell proliferation  positive regulation of gene expression  phosphatase inhibitor activity  lamellipodium  cell differentiation  positive regulation of granulocyte differentiation  positive regulation of sodium:proton antiporter activity  ruffle membrane  regulation of cell adhesion mediated by integrin  protein homodimerization activity  negative regulation of catalytic activity  positive regulation of megakaryocyte differentiation  positive regulation of transcription, DNA-templated  protein stabilization  protein maturation  cellular response to retinoic acid  protein targeting to plasma membrane  
Ontology : EGO-EBImagnesium ion binding  ruffle  protein kinase inhibitor activity  calcium ion binding  protein binding  nucleus  nucleus  cytoplasm  plasma membrane  negative regulation of protein kinase activity  negative regulation of cell proliferation  positive regulation of gene expression  phosphatase inhibitor activity  lamellipodium  cell differentiation  positive regulation of granulocyte differentiation  positive regulation of sodium:proton antiporter activity  ruffle membrane  regulation of cell adhesion mediated by integrin  protein homodimerization activity  negative regulation of catalytic activity  positive regulation of megakaryocyte differentiation  positive regulation of transcription, DNA-templated  protein stabilization  protein maturation  cellular response to retinoic acid  protein targeting to plasma membrane  
NDEx NetworkTESC
Atlas of Cancer Signalling NetworkTESC
Wikipedia pathwaysTESC
Orthology - Evolution
OrthoDB54997
GeneTree (enSembl)ENSG00000088992
Phylogenetic Trees/Animal Genes : TreeFamTESC
HOVERGENQ96BS2
HOGENOMQ96BS2
Homologs : HomoloGeneTESC
Homology/Alignments : Family Browser (UCSC)TESC
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTESC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TESC
dbVarTESC
ClinVarTESC
1000_GenomesTESC 
Exome Variant ServerTESC
ExAC (Exome Aggregation Consortium)TESC (select the gene name)
Genetic variants : HAPMAP54997
Genomic Variants (DGV)TESC [DGVbeta]
DECIPHER (Syndromes)12:117476728-117537251  ENSG00000088992
CONAN: Copy Number AnalysisTESC 
Mutations
ICGC Data PortalTESC 
TCGA Data PortalTESC 
Broad Tumor PortalTESC
OASIS PortalTESC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTESC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTESC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TESC
DgiDB (Drug Gene Interaction Database)TESC
DoCM (Curated mutations)TESC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TESC (select a term)
intoGenTESC
Cancer3DTESC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611585   
Orphanet
MedgenTESC
Genetic Testing Registry TESC
NextProtQ96BS2 [Medical]
TSGene54997
GENETestsTESC
Huge Navigator TESC [HugePedia]
snp3D : Map Gene to Disease54997
BioCentury BCIQTESC
ClinGenTESC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54997
Chemical/Pharm GKB GenePA143485630
Clinical trialTESC
Miscellaneous
canSAR (ICR)TESC (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTESC
EVEXTESC
GoPubMedTESC
iHOPTESC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:30:49 CET 2017

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